Methylene blue: Difference between revisions
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'''Methylene blue''' or '''methylthioninium chloride''' (MB) is a medication and dye that also functions as an [[antioxidant]].<ref name="CHEBI">{{Cite web|url=https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:6872|title=Methylene blue (CHEBI:6872)|last=|first=|authorlink=|last2=|first2=|authorlink2=|date=|website=Chemical Entities of Biological Interest|archive-url=|archive-date=|dead-url=|access-date=2020-11-29}}</ref><ref>{{Cite web|url=https://www.drugs.com/monograph/methylene-blue.html|title=Methylene Blue Monograph for Professionals|last=American Society of Health-System Pharmacists|first=|authorlink=|last2=|first2=|authorlink2=|date=|website=Drugs.com|language=en|archive-url=|archive-date=|dead-url=|access-date=2020-11-29}}</ref><ref>{{Cite web|url=https://go.drugbank.com/drugs/DB09241|title=Methylene blue|website=go.drugbank.com|access-date=2020-11-29}}</ref> | '''Methylene blue''' or '''methylthioninium chloride''' (MB) is a medication and dye that also functions as an [[antioxidant]].<ref name="CHEBI">{{Cite web|url=https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:6872|title=Methylene blue (CHEBI:6872)|last=|first=|authorlink=|last2=|first2=|authorlink2=|date=|website=Chemical Entities of Biological Interest|archive-url=|archive-date=|dead-url=|access-date=2020-11-29}}</ref><ref name=":0">{{Cite web|url=https://www.drugs.com/monograph/methylene-blue.html|title=Methylene Blue Monograph for Professionals|last=American Society of Health-System Pharmacists|first=|authorlink=|last2=|first2=|authorlink2=|date=|website=Drugs.com|language=en|archive-url=|archive-date=|dead-url=|access-date=2020-11-29}}</ref><ref>{{Cite web|url=https://go.drugbank.com/drugs/DB09241|title=Methylene blue|website=go.drugbank.com|access-date=2020-11-29}}</ref> | ||
==Theory == | ==Theory == | ||
Methylene blue is claimed to lead to better oxygenation of tissues, [[Mitochondria|mitochondrial]] protection and recovery, improved memory and [[cognitive dysfunction|cognition]]. | Methylene blue is claimed to lead to better oxygenation of tissues, [[Mitochondria|mitochondrial]] protection and recovery, improved memory and [[cognitive dysfunction|cognition]]. It is used sublingually by some [[ME/CFS]] patients. | ||
==Evidence== | ==Evidence== | ||
No clinical trials of methylene blue have been conducted in ME/CFS patients. | |||
==Clinicians== | ==Clinicians== | ||
==Risks and safety== | ==Risks and safety== | ||
Serotonin syndrome | Serotonin syndrome and a number of other serious side effects may result from the use of methylene blue. It also turns skin and mucosa a bluish color and urine a greenish blue color.<ref name=":0" /><ref>{{Cite journal|last=Ginimuge|first=Prashant R.|last2=Jyothi|first2=S.D.|date=2010|title=Methylene Blue: Revisited|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087269/|journal=Journal of Anaesthesiology, Clinical Pharmacology|volume=26|issue=4|pages=517–520|issn=0970-9185|pmc=3087269|pmid=21547182}}</ref> | ||
==Costs and availability== | ==Costs and availability== | ||
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*[https://go.drugbank.com/drugs/DB09241 Methylene blue] - drugbank.ca | *[https://go.drugbank.com/drugs/DB09241 Methylene blue] - drugbank.ca | ||
*[https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:6872 Methylene blue] - Chemical Entities of Biological Interest (ChEBI) | *[https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:6872 Methylene blue] - Chemical Entities of Biological Interest (ChEBI) | ||
*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087269/ Methylene blue: Revisited]- Journal of Anaesthesiology, Clinical Pharmacology | |||
==References == | ==References == | ||
{{Reflist}} | {{Reflist}} | ||
Revision as of 13:48, November 29, 2020
 | This article is a stub. |
Methylene blue or methylthioninium chloride (MB) is a medication and dye that also functions as an antioxidant.[1][2][3]
Theory[edit | edit source]
Methylene blue is claimed to lead to better oxygenation of tissues, mitochondrial protection and recovery, improved memory and cognition. It is used sublingually by some ME/CFS patients.
Evidence[edit | edit source]
No clinical trials of methylene blue have been conducted in ME/CFS patients.
Clinicians[edit | edit source]
Risks and safety[edit | edit source]
Serotonin syndrome and a number of other serious side effects may result from the use of methylene blue. It also turns skin and mucosa a bluish color and urine a greenish blue color.[2][4]
Costs and availability[edit | edit source]
See also[edit | edit source]
Learn more[edit | edit source]
- Methylene blue - drugs.com
- Methylene blue - drugbank.ca
- Methylene blue - Chemical Entities of Biological Interest (ChEBI)
- Methylene blue: Revisited- Journal of Anaesthesiology, Clinical Pharmacology
References[edit | edit source]
- ↑ "Methylene blue (CHEBI:6872)". Chemical Entities of Biological Interest. Retrieved November 29, 2020. Cite has empty unknown parameter:
|dead-url=(help) - ↑ 2.0 2.1 American Society of Health-System Pharmacists. "Methylene Blue Monograph for Professionals". Drugs.com. Retrieved November 29, 2020. Cite has empty unknown parameter:
|dead-url=(help) - ↑ "Methylene blue". go.drugbank.com. Retrieved November 29, 2020.
- ↑ Ginimuge, Prashant R.; Jyothi, S.D. (2010). "Methylene Blue: Revisited". Journal of Anaesthesiology, Clinical Pharmacology. 26 (4): 517–520. ISSN 0970-9185. PMC 3087269. PMID 21547182.
