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Menstrual cycle
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==Health effects in ME/CFS == Women with [[chronic fatigue syndrome]] report higher rates of [[polycystic ovarian syndrome]] (PCOS) and anovulatory cycles, and higher rates of [[endometriosis]].<ref name=":0">{{Cite journal | last = Allen | first = Peggy Rosati | date = Jul 2008 | title = Chronic fatigue syndrome: implications for women and their health care providers during the childbearing years|url=https://www.ncbi.nlm.nih.gov/pubmed/18586181|journal=Journal of Midwifery & Women's Health|volume=53|issue=4|pages=289β301; quiz 399|doi=10.1016/j.jmwh.2007.12.001|issn=1542-2011|pmid=18586181}}</ref> Women who develop [[ME/CFS]] have higher rates a history of [[irregular menstrual cycles]], [[amenorrhea]], [[dysmenorrhea]], [[anovolutory]] cycles and sporadic bleeding between periods.<ref name="canadianconsensus-CCC">{{Citation | last1 = Carruthers | first1 = Bruce M. | authorlink1 = Bruce Carruthers | last2 = Jain | first2 = Anil Kumar | authorlink2 = Anil Kumar Jain | last3 = De Meirleir | first3 = Kenny L. | authorlink3 = Kenny De Meirleir | last4 =Peterson | first4 = Daniel L. | authorlink4 = Daniel Peterson | last5 = Klimas | first5 = Nancy G. | authorlink5 = Nancy Klimas | last6 = Lerner | first6 = A. Martin | authorlink6 = Martin Lerner | last7 =Bested | first7 = Alison C. | authorlink7 = Alison Bested | last8 = Flor-Henry | first8 = Pierre | authorlink8 = Pierre Flor-Henry | last9 = Joshi | first9 = Pradip | authorlink9 = Pradip Joshi | last10 = Powles | first10 = AC Peter | authorlink10 = A C Peter Powles | last11 = Sherkey | first11 = Jeffrey A. | authorlink11 = Jeffrey Sherkey | last12 = van de Sande | first12 = Marjorie I. | authorlink12 = Marjorie van de Sande | title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols| journal = Journal of Chronic Fatigue Syndrome | volume = 11 | issue = 2 | pages = 7-115 | date = 2003 | pmid = | doi = 10.1300/J092v11n01_02| url = http://www.investinme.org/Documents/PDFdocuments/CanadianDefinitionME-CFS.pdf}}</ref><ref>{{Cite journal | last = Komaroff|first = AnthonyL | last2 = Dailey | first2 = Christine | last3 = Hall | first3 = JanetE | last4 = Signorello | first4 = LisaB | last5 = Harlow | first5 = BernardL | date = 1998-09-28 | title = Reproductive correlates of chronic fatigue syndrome|url=https://www.amjmed.com/article/S0002-9343(98)00173-9/abstract|journal=The American Journal of Medicine|language=English|volume=105|issue=3 | pages = 94Sβ99S|doi=10.1016/S0002-9343(98)00173-9|issn=0002-9343}}</ref> Numerous outbreaks of [[epidemic myalgic encephalomyelitis]] noted [[Menstrual problems in ME/CFS|menstrual irregularities]] and a tendency toward relapse before or during menstruation.<ref name="Shelokov, 1957">{{Citation | last = Shelokov | first1 = Alexis | authorlink1 = | last2 = Habel | first2 = Karl | authorlink2 = | last3 = Verder | first3 = Elizabeth | authorlink3 = | last4 =Welsh | first4 = William | author-link4 = | title = Epidemic Neuromyasthenia β An Outbreak of Poliomyelitis-like Illness in Student Nurses | journal = New England Journal of Medicine | volume = | issue = 257 | page = 345-355 | date = August 1957 | doi = 10.1056/NEJM195708222570801 }}</ref><ref name=":1">{{Cite journal | last = Albrecht | first = Robert | date = March 21, 1964 | title = Epidemic Neuromyasthenia Outbreak in a Convent in New York State|url=https://www.ncbi.nlm.nih.gov/pubmed/14100144|journal=Journal of the American Medical Association|volume=187 | pages = 904-907|via=}}</ref><ref name="Poskanzer, 19572">{{Citation | last = Poskanzer | first1 = David C. | authorlink1 = | last2 = Henderson | first2 = Donald A. | authorlink2 = | last3 = Kunkle | first3 = E. Charles | authorlink3 = | last4 = Kalter | first4 = Seymour S. | authorlink4 = | last5 =Clement | first5 = Walter B. | authorlink5 = | last6 = Bond | first6 = James O. | authorlink6 = | title = Epidemic Neuromyasthenia β An Outbreak in Punta Gorda, Florida | journal = New England Journal of Medicine | volume = | issue = 257 | page = 356-364 | date = 1957 | pmid = 13464939 | doi = 10.1056/NEJM195708222570802 | url = http://www.nejm.org/doi/full/10.1056/NEJM195708222570802 }}</ref> {{See also|Menstrual problems in ME/CFS}}
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