ME/CFS

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What is ME/CFS By Open Medicine Foundation - OMF. Linda Tannenbaum, Founder & CEO/President, talks about ME/CFS and how OMF is leading research and delivering hope (2018)

The acronym ME/CFS is commonly used as an umbrella term to cover the various case definitions employed to describe myalgic encephalomyelitis (ME) and/or chronic fatigue syndrome (CFS). Case definitions vary widely, with some being so broad as to cover numerous unrelated illnesses.[1] Even among the narrower case definitions, it is unclear if ME is equivalent to CFS, is a specific form of it, or something entirely different. In ME/CFS research, the terms are often used synonymously, though there is no clear evidence to support either equating them or separating them.

ME was the original name for CFS; the names are used interchangeably or with the acronym ME/CFS.[2] United States (US) government bodies now use the acronym.[3] The US Centers for Disease Control and Prevention's (CDC) website page is Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).[4] The acronym CFS/ME is used by the National Health Service (NHS) in the United Kingdom.[5] The CDC recognizes ME/CFS as a "disabling and complex disease"[6] 

"The most common overlapping condition with ME/CFS is fibromyalgia."[7][8] While some have posited ME/CFS and fibromyalgia are variants of the same illness, Benjamin Natelson, MD summoned considerable amounts of data that suggest the two illnesses differ with different pathophysiologic processes leading to different treatments.[9]

See also[edit | edit source]

Case definitions for ME/CFS

  • Canadian Consensus Criteria (CCC)[10] A diagnosis of moderate and severe forms of ME/CFS are accurately made using this criterion. Adults can be diagnosed at 6 months while pediatric cases are diagnosed at three months.

Case definition for ME

Learn more[edit | edit source]

Persons living with ME/CFS

References[edit | edit source]

  1. "What is Chronic Fatigue Syndrome & Myalgic Encephalomyelitis? - Prohealth". Prohealth. Retrieved August 11, 2018.
  2. Dellwo, Adrienne (November 24, 2018). "Myalgic Encephalomyelitis or Chronic Fatigue Syndrome". Verywell Health. Retrieved November 28, 2018. Cite has empty unknown parameter: |dead-url= (help)
  3. "Biomarker Research Advances in 'Chronic Fatigue Syndrome". Medscape.com. November 8, 2016. Retrieved February 7, 2019. The condition, now called myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) by US government bodies, Cite has empty unknown parameter: |dead-url= (help)
  4. "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | CDC". www.cdc.gov. July 3, 2018. Retrieved September 7, 2018.
  5. "Chronic fatigue syndrome (CFS/ME)". nhs.uk. Retrieved August 13, 2018.
  6. "What is ME/CFS? | Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | CDC". www.cdc.gov. January 18, 2019. Retrieved April 12, 2019.
  7. "Overlapping Conditions - American Myalgic Encephalomyelitis and Chronic Fatigue Syndrome Society". ammes.org. Retrieved August 12, 2018. Cite has empty unknown parameter: |dead-url= (help)
  8. Jason, Leonard; Taylor, R.R.; Kennedy, C.L.; Song, S; Johnson, D; Torres, S.R. (January 1, 2001). "Chronic fatigue syndrome: Comorbidity with fibromyalgia and psychiatric illness". Medicine and Psychiatry. 4: 29–34.
  9. Natelson, Benjamin H. (February 19, 2019). "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Fibromyalgia: Definitions, Similarities, and Differences". Clinical Therapeutics. 0 (0). doi:10.1016/j.clinthera.2018.12.016. ISSN 0149-2918. PMID 30795933.
  10. Carruthers, Bruce M.; Jain, Anil Kumar; De Meirleir, Kenny L.; Peterson, Daniel L.; Klimas, Nancy G.; Lerner, A. Martin; Bested, Alison C.; Flor-Henry, Pierre; Joshi, Pradip; Powles, A C Peter; Sherkey, Jeffrey A.; van de Sande, Marjorie I. (2003), "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols" (PDF), Journal of Chronic Fatigue Syndrome, 11 (2): 7-115, doi:10.1300/J092v11n01_02
  11. Clayton, Ellen Wright; Alegria, Margarita; Bateman, Lucinda; Chu, Lily; Cleeland, Charles; Davis, Ronald; Diamond, Betty; Ganiats, Theodore; Keller, Betsy; Klimas, Nancy; Lerner, A Martin; Mulrow, Cynthia; Natelson, Benjamin; Rowe, Peter; Shelanski, Michael (2015). "Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - Redefining an Illness" (PDF). nationacademies.org. Cite has empty unknown parameter: |dead-url= (help)
  12. Carruthers, Bruce M.; van de Sande, Marjorie I.; De Meirleir, Kenny L.; Klimas, Nancy G.; Broderick, Gordon; Mitchell, Terry; Staines, Donald; Powles, A. C. Peter; Speight, Nigel; Vallings, Rosamund; Bateman, Lucinda; Baumgarten-Austrheim, Barbara; Bell, David; Carlo-Stella, Nicoletta; Chia, John; Darragh, Austin; Jo, Daehyun; Lewis, Donald; Light, Alan; Marshall-Gradisnik, Sonya; Mena, Ismael; Mikovits, Judy; Miwa, Kunihisa; Murovska, Modra; Pall, Martin; Stevens, Staci (August 22, 2011). "Myalgic encephalomyelitis: International Consensus Criteria". Journal of Internal Medicine. 270 (4): 327–338. doi:10.1111/j.1365-2796.2011.02428.x. ISSN 0954-6820. PMC 3427890. PMID 21777306.