Lubov Nathanson

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Lubov Nathanson, PhD, is an assistant professor in the College of Osteopathic Medicine’s Institute for Neuro-Immune Medicine (INIM), Nova Southeastern University, Florida, US.[1]

Dr Nathanson research interests include exploring altered genetic expression in the immune cells of ME/CFS patients and the potential role of DNA methylation, an epigenetic process that can turn genes on or off, in ME/CFS.

2017 Ramsay Award[edit | edit source]

A team comprised of Dr. Elisa Oltra of Universidad Católica de Valencia, Spain, and Drs. Lubov Nathanson, Vladimir Beljanski and Malav Suchin Trivedi of Nova Southeastern University, US, were awarded a 2017 Ramsay Award grant from the Solve ME/CFS Initiative for researching the effect of ME/CFS on epigenetic regulation in specific immune cell types.[2]

ME/CFS Common Data Element (CDE) Project[edit | edit source]

Member of the Baseline/Covariate Working Group, the Neurologic/Cognitive/CNS Imaging Working Group, and the Biomarkers Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the National Institute of Neurological Disorders and Stroke and the Centers for Disease Control and Prevention.[3] This working group reviewed data collection instruments widely used by investigators in the ME/CFS field, and either recommended their use unchanged or (more often) proposed some modifications.[4]

Notable studies[edit | edit source]

  • 2015, Using gene expression signatures to identify novel treatment strategies in gulf war illness[5] - (Full text)
  • 2018, Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns[6] - (Full Text)
  • 2019, Treatment Avenues in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Split-gender Pharmacogenomic Study of Gene-expression Modules[7] - (Abstract)
  • 2019, Epigenetic Components of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Uncover Potential Transposable Element Activation[8] - (Full text)
  • 2019, Genetic Predisposition for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study[9] - (Abstract)
  • 2020, Assessing diagnostic value of microRNAs from peripheral blood mononuclear cells and extracellular vesicles in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[10] - (Full text)
  • 2020, Unravelling myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Gender‐specific changes in the microRNA expression profiling in ME/CFS[11] - (Full text)

Talks and interviews[edit | edit source]

Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. "NSU Research Spotlight: Lubov Nathanson, Ph.D. | NSU Newsroom". nsunews.nova.edu. Retrieved April 9, 2019.
  2. "2017 Ramsay Award Program Results". Solve ME/CFS Initiative. Retrieved March 29, 2019.
  3. "Complete Myalgic Encephalomyelitis/Chronic Fatigue Syndrome CDE Roster". NIH. Retrieved October 11, 2019.
  4. "NINDS CDE Project: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Baseline/Covariate Information Subgroup" (PDF). ninds.nih.gov. Retrieved March 4, 2020.
  5. Craddock, Travis J.A.; Harvey, Jeanna M.; Nathanson, Lubov; Barnes, Zachary M.; Klimas, Nancy G.; Fletcher, Mary Ann; Broderick, Gordon (July 9, 2015). "Using gene expression signatures to identify novel treatment strategies in gulf war illness". BMC Medical Genomics. 8. doi:10.1186/s12920-015-0111-3. ISSN 1755-8794. PMC 4495687. PMID 26156520.
  6. Trivedi, Malav S.; Oltra, Elisa; Sarria, Leonor; Rose, Natasha; Beljanski, Vladimir; Fletcher, Mary Ann; Klimas, Nancy G.; Nathanson, Lubov (July 2018). "Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns". PlosOne. doi:10.1371/journal.pone.0201066.
  7. Jeffrey, Mary G.; Nathanson, Lubov; Aenlle, Kristina; Barnes, Zachary M.; Baig, Mirza; Broderick, Gordon; Klimas, Nancy G.; Fletcher, Mary Ann; Craddock, Travis J.A. (March 2019). "Treatment Avenues in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Split-gender Pharmacogenomic Study of Gene-expression Modules". Clinical Therapeutics. doi:10.1016/j.clinthera.2019.01.011.
  8. Almenar-Pérez, Eloy; Ovejero, Tamara; Sánchez-Fito, Teresa; Espejo, José A.; Nathanson, Lubov; Oltra, Elisa (April 2019). "Epigenetic Components of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Uncover Potential Transposable Element Activation". Clinical Therapeutics. 41 (4): 675–698. doi:10.1016/j.clinthera.2019.02.012.
  9. Perez, Melanie; Jaundoo, Rajeev; Hilton, Kelly; Del Alamo, Ana; Gemayel, Kristina; Klimas, Nancy G.; Craddock, Travis J.; Nathanson, Lubov (May 2019). "Genetic Predisposition for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study". Frontiers in Pediatrics. 7: 206. doi:10.3389/fped.2019.00206.
  10. Almenar-Pérez, Eloy; Sarría, Leonor; Nathanson, Lubov; Oltra, Elisa (December 2020). "Assessing diagnostic value of microRNAs from peripheral blood mononuclear cells and extracellular vesicles in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Scientific Reports. 10 (1): 2064. doi:10.1038/s41598-020-58506-5. ISSN 2045-2322.
  11. Cheema, Amanpreet K.; Sarria, Leonor; Bekheit, Mina; Collado, Fanny; Almenar‐Pérez, Eloy; Martín‐Martínez, Eva; Alegre, Jose; Castro‐Marrero, Jesus; Fletcher, Mary A.; Klimas, Nancy; Oltra, Elisa; Nathanson, Lubov (April 14, 2020). "Unravelling myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): Gender-specific changes in the microRNA expression profiling in ME/CFS". Journal of Cellular and Molecular Medicine. 00: 1–13. doi:10.1111/jcmm.15260. ISSN 1582-4934. PMID 32291908.