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List of systematic reviews about ME/CFS/SEID
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== Treatments == ===Randomized controlled trial reviews=== *2020, Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)<ref name="Kim2020">{{Cite journal | last = Kim|first = Do-Young | authorlink = | last2 = Lee | first2 = Jin-Seok | authorlink2 = | last3 = Park | first3 = Samuel-Young | authorlink3 = | last4 = Kim | first4 = Soo-Jin | authorlink4 = | last5 = Son | first5 = Chang-Gue | authorlink5 = | date = 2020-01-06 | title = Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)|url=https://doi.org/10.1186/s12967-019-02196-9|journal=Journal of Translational Medicine|volume=18|issue=1|pages=1-12|doi=10.1186/s12967-019-02196-9|issn=1479-5876|pmc = 6943902|pmid=31906979|access-date=|quote=|via=}}</ref> - [https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-02196-9 (Full text)] *2020, Assessment of the scientific rigour of randomized controlled trials on the effectiveness of cognitive behavioural therapy and graded exercise therapy for patients with myalgic encephalomyelitis/chronic fatigue syndrome: A systematic review<ref>{{Cite journal | last = Ahmed | first = SA | last2 = Mewes | first2 = JC | last3 = Vrijhoef | first3 = HJM | date = 2020-02-01 | title = Assessment of the scientific rigour of randomized controlled trials on the effectiveness of cognitive behavioural therapy and graded exercise therapy for patients with myalgic encephalomyelitis/chronic fatigue syndrome: A systematic review | url =https://doi.org/10.1177/1359105319847261|journal=Journal of Health Psychology|language=en|volume=25|issue=2|pages=240–255|doi=10.1177/1359105319847261|issn=1359-1053}}</ref> - [https://www.researchgate.net/publication/333003056_Assessment_of_the_scientific_rigour_of_randomized_controlled_trials_on_the_effectiveness_of_cognitive_behavioural_therapy_and_graded_exercise_therapy_for_patients_with_myalgic_encephalomyelitischronic (Abstract)] ===Drug and Chinese medicine systematic reviews=== *2020, Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)<ref name="Kim2020" /> - [https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-02196-9 (Full text)] *2016, A Systematic Review of Drug Therapies for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis<ref>{{Cite journal | last = Collatz|first = Ansel | last2 = Johnston | first2 = Samantha C. | last3 = Staines | first3 = Donald R. | last4 = Marshall-Gradisnik | first4 = Sonya M. | date = 2016-06-01 | title = A Systematic Review of Drug Therapies for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis|url=http://www.sciencedirect.com/science/article/pii/S014929181630306X|journal=Clinical Therapeutics|language=en|volume=38|issue=6|pages=1263–1271.e9|doi=10.1016/j.clinthera.2016.04.038|issn=0149-2918}}</ref> - [https://www.sciencedirect.com/science/article/pii/S014929181630306X (Full text)] *2014, Traditional Chinese medicine for chronic fatigue syndrome: a systematic review of randomized clinical trials<ref>{{Cite journal | last = Wang|first = Yu-Yi | last2 = Li | first2 = Xin-Xue | last3 = Liu | first3 = Jian-Ping | last4 = Luo | first4 = Hui | last5 = Ma | first5 = Li-Xin | last6 = Alraek | first6 = Terje | date = 2014-08-01 | title = Traditional Chinese medicine for chronic fatigue syndrome: A systematic review of randomized clinical trials|url=http://www.sciencedirect.com/science/article/pii/S0965229914001022|journal=Complementary Therapies in Medicine|language=en|volume=22|issue=4 | pages = 826–833|doi=10.1016/j.ctim.2014.06.004|issn=0965-2299}}</ref> - [https://www.sciencedirect.com/science/article/pii/S0965229914001022 (Abstract)] ===Diet or nutritional supplement reviews=== *2021, A systematic review of nutraceutical interventions for mitochondrial dysfunctions in myalgic encephalomyelitis/chronic fatigue syndrome<ref name="Maksoud2021b">{{Cite journal | title = A systematic review of nutraceutical interventions for mitochondrial dysfunctions in myalgic encephalomyelitis/chronic fatigue syndrome | date = 2021-02-17|url=https://doi.org/10.1186/s12967-021-02742-4|journal=Journal of Translational Medicine|volume=19|issue=1 | pages = 81 | last = Maksoud | first = Rebekah | authorlink = | last2 = Balinas | first2 = Cassandra | authorlink2 = | last3 = Holden | first3 = Sean | authorlink3 = | last4 = Cabanas | first4 = Hélène | authorlink4 = Hélène Cabanas | last5 = Staines | first5 = Donald | authorlink5 = Donald Staines | last6 = Marshall-Gradisnik | first6 = Sonya | authorlink6 = Sonya Marshall-Gradisnik|doi=10.1186/s12967-021-02742-4|pmc=PMC7890871|pmid=33596913|access-date=|issn=1479-5876|quote=|via=}}</ref> - [https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-02742-4 (Full text)] *2018, Are probiotic treatments useful on fibromyalgia syndrome or chronic fatigue syndrome patients? A systematic review<ref>{{Cite web|url=https://www.ingentaconnect.com/content/wagac/bm/2018/00000009/00000004/art00007 | title = Are probiotic treatments useful on fibromyalgia syndrome or chronic fatigue syndrome patients? A systematic review | last = Roman | first = P. | last2 = Carrillo-Trabalón | first2 = F. | date = 2018-06-15 | website = ingentaconnect.com|language=en|access-date=2020-07-12 | last3 = Sánchez-Labraca | first3 = N. | last4 = Cañadas | first4 = F. | last5 = Estévez | first5 = A.F. |last6 = Cardona | first6 = D.}}</ref> - [https://www.ingentaconnect.com/content/wagac/bm/2018/00000009/00000004/art00007 (Abstract)] *2020, Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)<ref name="Kim2020" /> - [https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-02196-9 (Full text)] *2017, Dietary and nutrition interventions for the therapeutic treatment of chronic fatigue syndrome/myalgic encephalomyelitis: a systematic review<ref>{{Cite journal | last = Campagnolo|first = N. | last2 = Johnston | first2 = S. | last3 = Collatz | first3 = A. | last4 = Staines | first4 = D. | last5 = Marshall‐Gradisnik | first5 = S. | date = 2017 | title=Dietary and nutrition interventions for the therapeutic treatment of chronic fatigue syndrome/myalgic encephalomyelitis: a systematic review | url =https://onlinelibrary.wiley.com/doi/abs/10.1111/jhn.12435|journal=Journal of Human Nutrition and Dietetics|language=en|volume=30|issue=3|pages=247–259|doi=10.1111/jhn.12435|issn=1365-277X|pmid=28111818|pmc=5434800|quote=|via=}}</ref> - [https://onlinelibrary.wiley.com/doi/abs/10.1111/jhn.12435 (Full text)] *2017, Role of dietary modification in alleviating chronic fatigue syndrome symptoms: a systematic review<ref name="Jones2017">{{Cite journal | title = Role of dietary modification in alleviating chronic fatigue syndrome symptoms: a systematic review | date = 2017 | url=https://onlinelibrary.wiley.com/doi/abs/10.1111/1753-6405.12670|journal=Australian and New Zealand Journal of Public Health|volume=41|issue=4 | pages = 338–344 | last = Jones | first = Kathryn | last2 = Probst | first2 = Yasmine|language=en|doi=10.1111/1753-6405.12670|issn=1753-6405}}</ref> - [https://onlinelibrary.wiley.com/doi/abs/10.1111/1753-6405.12670 (Full text)] *2016, A systematic review of probiotic interventions for gastrointestinal symptoms and irritable bowel syndrome in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)<ref>{{Cite journal | last = Corbitt | first = Matthew | last2 = Campagnolo | first2 = N. | last3 = Staines | first3 = D. | last4 = Marshall-Gradisnik | first4 = S. | date = 2018-09-01 | title = A Systematic Review of Probiotic Interventions for Gastrointestinal Symptoms and Irritable Bowel Syndrome in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)|url=https://doi.org/10.1007/s12602-018-9397-8|journal=Probiotics and Antimicrobial Proteins|language=en|volume=10|issue=3 | pages = 466–477|doi=10.1007/s12602-018-9397-8|issn=1867-1314}}</ref> - [https://link.springer.com/article/10.1007/s12602-018-9397-8 (Abstract)] ===Alternative or complementary therapies=== *2020, Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)<ref name="Kim2020" /> - [https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-02196-9 (Full text)] * 2011, Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review<ref>{{Cite journal | last = Alraek|first = Terje | last2 = Lee | first2 = Myeong Soo | last3 = Choi | first3 = Tae-Young | last4 = Cao | first4 = Huijuan | last5 = Liu | first5 = Jianping | date = 2011-10-07 | title = Complementary and alternative medicine for patients with chronic fatigue syndrome: A systematic review | url =https://doi.org/10.1186/1472-6882-11-87|journal=BMC Complementary and Alternative Medicine|language=en|volume=11|issue=1 | pages = 87|doi=10.1186/1472-6882-11-87|issn=1472-6882|pmc = 3201900|pmid=21982120}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201900/ (Full text)] ===Psychological, behavioral and exercise treatment reviews=== *2022, Is It Useful to Question the Recovery Behaviour of Patients with ME/CFS or Long COVID?<ref name="Vink2022review">{{Cite journal | title = Is It Useful to Question the Recovery Behaviour of Patients with ME/CFS or Long COVID? | date = Feb 2022|url=https://www.mdpi.com/2227-9032/10/2/392|journal=Healthcare|volume=10|issue=2 | pages = 392 | last = Vink|first = Mark | authorlink = Mark Vink | last2 = Vink-Niese | first2 = Friso | authorlink2 = Friso Vink-Niese|language=en|doi=10.3390/healthcare10020392|pmc=|pmid=|access-date=|issn=2227-9032|quote=|via=}}</ref> - [https://www.mdpi.com/2227-9032/10/2/392/htm (Full text)] *2021, Systematic Review of Mind-Body Interventions to Treat Myalgic Encephalomyelitis/Chronic Fatigue Syndrome<ref name="Ardestani2021">{{Cite journal | title = Systematic Review of Mind-Body Interventions to Treat Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | date = Jun 24, 2021|url=https://www.mdpi.com/1648-9144/57/7/652|journal=Medicina|volume=57|issue=7 | pages = 652 | last = Khanpour Ardestani|first = Samaneh | authorlink = | last2 = Karkhaneh | first2 = Mohammad | authorlink2 = | last3 = Stein | first3 = Eleanor | authorlink3 = Eleanor Stein | last4 = Punja | first4 = Salima | authorlink4 = | last5 = Junqueira | first5 = Daniela R. | authorlink5 = | last6 = Kuzmyn | first6 = Tatiana | authorlink6 = | last7 = Pearson | first7 = Michelle | last8 = Smith | first8 = Laurie | last9 = Olson | first9 = Karin | last10 = Vohra | first10 = Sunita|language=en|doi=10.3390/medicina57070652|pmc=PMC8305555|pmid=34202826|access-date=|issn=1648-9144|quote=|via=}}</ref> - [https://www.mdpi.com/1648-9144/57/7/652/htm (Full text)] *2020, Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)<ref name="Kim2020" /> - [https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-02196-9 (Full text)] *2019, Work Rehabilitation and Medical Retirement for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients. A Review and Appraisal of Diagnostic Strategies<ref name="Vink2019rehab">{{Cite journal | last = Vink | last2 = Vink-Niese | date = 2019-09-20 | title = Work Rehabilitation and Medical Retirement for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients. A Review and Appraisal of Diagnostic Strategies|url=https://www.mdpi.com/2075-4418/9/4/124|journal=Diagnostics|language=en|volume=9|issue=4|pages=124|doi=10.3390/diagnostics9040124|issn=2075-4418|first = Mark | first2 = Alexandra|pmc=|pmid=|quote= | author-link = Mark Vink | authorlink2 = Alexandra Vink-Niese|access-date=|via=}}</ref> - [https://www.mdpi.com/2075-4418/9/4/124/htm (Full text)] *2019, Cognitive behavioural therapy for myalgic encephalomyelitis/chronic fatigue syndrome is not effective. Re-analysis of a Cochrane review<ref name="Vink2019CBT">{{Cite journal | title = Cognitive behavioural therapy for myalgic encephalomyelitis/chronic fatigue syndrome is not effective. Re-analysis of a Cochrane review | date = Jan 2019|url=https://journals.sagepub.com/doi/full/10.1177/2055102919840614|journal=Health Psychology Open|volume=6|issue=1|pages=205510291984061 | last = Vink|first = Mark | authorlink = Mark Vink | last2 = Vink-Niese | first2 = Alexandra | authorlink2 = |doi=10.1177/2055102919840614|pmc=PMC6498783|pmid=31080632|access-date=|issn=2055-1029|quote=|via=}}</ref> - [https://journals.sagepub.com/doi/full/10.1177/2055102919840614 (Full text)] *2018, Rethinking the treatment of chronic fatigue syndrome — A reanalysis and evaluation of findings from a recent major trial of graded exercise and CBT<ref name="Wilshire2018">{{Cite journal | last = Wilshire | first1 = C | authorlink1 = Carolyn Wilshire | last2 = Kindlon | first2 = T | authorlink2 = Tom Kindlon | last3 = Courtney | first3 = R | authorlink3 = Robert Courtney | last4 = Matthees | first4 = A | authorlink4 = Alem Matthees | last5 = Tuller | first5 = D | authorlink5 = David Tuller | last6 = Geraghty | first6 = K | authorlink6 = Keith Geraghty | last7 =Levin | first7 = B | authorlink7 = Bruce Levin | title = Rethinking the treatment of chronic fatigue syndrome—A reanalysis and evaluation of findings from a recent major trial of graded exercise and CBT | journal = BMC Psychology | volume = 6 | issue = 6 | page = | date = 2018 | doi = 10.1186/s40359-018-0218-3 | url = https://www.researchgate.net/publication/322568480_Rethinking_the_treatment_of_chronic_fatigue_syndrome-A_reanalysis_and_evaluation_of_findings_from_a_recent_major_trial_of_graded_exercise_and_CBT }}</ref> - [https://www.researchgate.net/publication/322568480_Rethinking_the_treatment_of_chronic_fatigue_syndrome-A_reanalysis_and_evaluation_of_findings_from_a_recent_major_trial_of_graded_exercise_and_CBT (Full Text)] *2018, Graded exercise therapy for myalgic encephalomyelitis/chronic fatigue syndrome is not effective and unsafe. Re-analysis of a Cochrane review<ref name="Vink2018GET">{{Cite journal | last = Vink|first = Mark | authorlink = Mark Vink | last2 = Vink-Niese | first2 = Alexandra | date = Jul 2018 | title = Graded exercise therapy for myalgic encephalomyelitis/chronic fatigue syndrome is not effective and unsafe. Re-analysis of a Cochrane review | url =https://www.ncbi.nlm.nih.gov/pubmed/30305916|journal=Health Psychology Open|volume=5|issue=2|pages=2055102918805187|doi=10.1177/2055102918805187|issn=2055-1029|pmc=|pmid=30305916|via=|quote= | authorlink2 = Alexandra Vink-Niese}}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176540/ (Full Text)] *2017, Assessment of Individual PACE Trial Data: in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Cognitive Behavioral and Graded Exercise Therapy are Ineffective, Do Not Lead to Actual Recovery and Negative Outcomes may be Higher than Reported<ref name="Vinl2017data">{{Cite journal | last = Vink|first = Mark | date = 2017 | title=Assessment of Individual PACE Trial Data in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Cognitive Behavioual Therapy and Graded Exercise Therapy are Ineffective, Do Not Lead to Actual Recovery and Negative Outcomes may be Higher than Reported | url =https://www.researchgate.net/publication/312328779_Assessment_of_Individual_PACE_Trial_Data_in_Myalgic_EncephalomyelitisChronic_Fatigue_Syndrome_Cognitive_Behavioral_and_Graded_Exercise_Therapy_are_Ineffective_Do_Not_Lead_to_Actual_Recovery_and_Negati|journal=J Neuro Neurobiol|volume=3|issue=1|pages=|doi=10.16966/2379-7150.136|quote=|via=}}</ref> [https://www.researchgate.net/publication/312328779_Assessment_of_Individual_PACE_Trial_Data_in_Myalgic_EncephalomyelitisChronic_Fatigue_Syndrome_Cognitive_Behavioral_and_Graded_Exercise_Therapy_are_Ineffective_Do_Not_Lead_to_Actual_Recovery_and_Negati (Full text)] *2018, The effect of physiotherapy on fatigue and physical functioning in chronic fatigue syndrome patients: a systematic review<ref name="Galeoto2018" /> - [https://www.researchgate.net/profile/Giovanni-Galeoto-2/publication/327286068_The_effect_of_physiotherapy_on_fatigue_and_physical_functioning_in_chronic_fatigue_syndrome_patients_A_systematic_review/links/5ba00a6b299bf13e6038a80b/The-effect-of-physiotherapy-on-fatigue-and-physical-functioning-in-chronic-fatigue-syndrome-patients-A-systematic-review.pdf (Full text)] *2017, Do evidence based interventions for chronic fatigue syndrome improve sleep? A systematic review and narrative synthesis<ref>{{Cite journal | last = Russell|first = Charlotte | last2 = Kyle | first2 = Simon D. | last3 = Wearden | first3 = Alison J. | date = 2017-06-01 | title = Do evidence based interventions for chronic fatigue syndrome improve sleep? A systematic review and narrative synthesis|url=http://www.sciencedirect.com/science/article/pii/S1087079216300120|journal=Sleep Medicine Reviews|language=en|volume=33|pages=101–110|doi=10.1016/j.smrv.2016.05.001|issn=1087-0792}}</ref> - [https://ora.ox.ac.uk/objects/uuid:0281d447-f267-4ce2-8c77-7eef95bfd8a9/download_file?safe_filename=Russell_CFS_SMR.pdf&file_format=application%2Fpdf (Full text)] *2009, A review on cognitive behavorial therapy (CBT) and graded exercise therapy (GET) in myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS): CBT/GET is not only ineffective and not evidence-based, but also potentially harmful for many patients with ME/CFS<ref name="TwiskMaes2009">{{Cite web|url=https://pubmed.ncbi.nlm.nih.gov/19855350/ | title = A Review on Cognitive Behavorial Therapy (CBT) and Graded Exercise Therapy (GET) in Myalgic Encephalomyelitis (ME) / Chronic Fatigue Syndrome (CFS): CBT/GET Is Not Only Ineffective and Not Evidence-Based, but Also Potentially Harmful for Many Patients With ME/CFS | last = Twisk|first = Frank N | authorlink = Frank Twisk | last2 = Maes | first2 = Michael | authorlink2 = Michael Maes | date = 2009 | website = Neuro endocrinology letters|language=en|pmid=19855350|archive-url=|archive-date=|url-status=|access-date=2020-05-25}}</ref> - [http://www.me-foreningen.info/wp-content/uploads/2016/09/Review-on-CBT-GET-in-MECFS-not-only-Ineffective-Evidence-based-but-also-Harmful-for-Patients-Twisk.pdf (Full text)] ===Other treatment reviews=== *2020, Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)<ref name="Kim2020" /> - [https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-02196-9 (Full text)] *2018, The effect of physiotherapy on fatigue and physical functioning in chronic fatigue syndrome patients: a systematic review<ref name="Galeoto2018">{{Cite journal | title = The effect of physiotherapy on fatigue and physical functioning in chronic fatigue syndrome patients: A systematic review | date = Sep 2018|url=https://pubmed.ncbi.nlm.nih.gov/30151552/|journal=La Clinica Terapeutica|volume=169|issue=4| pages = e184–e188 | last = Galeoto|first = G. | authorlink = | last2 = Sansoni | first2 = J. | authorlink2 = | last3 = Valenti | first3 = D. | authorlink3 = | last4 = Mollica | first4 = R. | authorlink4 = | last5 = Valente | first5 = D. | authorlink5 = | last6 = Parente | first6 = M. | authorlink6 = | last7 = Servadio | first7 = A.|doi=10.7417/T.2018.2076|pmc=|pmid=30151552|access-date=|issn=1972-6007|quote=|via=}}</ref> - [https://www.researchgate.net/profile/Giovanni-Galeoto-2/publication/327286068_The_effect_of_physiotherapy_on_fatigue_and_physical_functioning_in_chronic_fatigue_syndrome_patients_A_systematic_review/links/5ba00a6b299bf13e6038a80b/The-effect-of-physiotherapy-on-fatigue-and-physical-functioning-in-chronic-fatigue-syndrome-patients-A-systematic-review.pdf (Full text)] *2015, [[Pathways to prevention report]] - Treatment of myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review for a National Institutes of Health Pathways to Prevention Workshop<ref>{{Cite journal | last = Smith|first = M.E. Beth | last2 = Haney | first2 = Elizabeth | last3 = McDonagh | first3 = Marian | last4 = Pappas | first4 = Miranda | last5 = Daeges | first5 = Monica | last6 = Wasson | first6 = Ngoc | last7 = Fu | first7 = Rongwei | last8 = Nelson | first8 = Heidi D. | date = 2015-06-16 | title = Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Systematic Review for a National Institutes of Health Pathways to Prevention Workshop | url =https://www.acpjournals.org/doi/10.7326/M15-0114|journal=Annals of Internal Medicine|volume=162|issue=12 | pages = 841–850|doi=10.7326/M15-0114|issn=0003-4819}}</ref> - [https://annals.org/aim/fullarticle/2322801 (Full text)] * 2003, [[York Review]] - Interventions for the treatment, management and rehabilitation of patients with chronic fatigue syndrome/myalgic encephalomyelitis: an updated systematic review - [[York Review|(Full text)]] * 2006, [[York Review]] - Interventions for the treatment, management and rehabilitation of patients with chronic fatigue syndrome/myalgic encephalomyelitis: an updated systematic review - [[York Review|(Full text)]] ::The '''York Review''' was used as the evidence based for the UK's 2007 NICE guidelines, and was based on data provided by [[Simon Wessely]]. :*2006, Inadequacy of the York (2005) Systematic Review of the CFS/ME Medical Evidence Base [http://www.resime.org/Documents/Hooper%20Inadequacy%20of%20the%20York%20%20Review.doc (Full text)]
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