List of clinical laboratory tests: Difference between revisions

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There are no established biomarkers for [[myalgic encephalomyelitis]] or many of its [[comorbidities]]. The following are clinically available lab tests used by some practitioners to aid in differential diagnosis or management of patients’ condition.
There are no established biomarkers for [[myalgic encephalomyelitis]] or many of its [[comorbidities]]. The following are clinically available lab tests used by some practitioners to aid in differential diagnosis or management of patients’ condition.
{| class="wikitable"
!Test name
!Type
!Description
!Rationale
!Relevant diagnoses
!Commercial availability
|-
|[[Matrix metalloproteinase]]-9
|Serum
|MMP-9 is a marker of inflammation, tissue remodeling, wound healing, and mobilization of tissue-bound growth factors and cytokines. Its expression correlates with abnormal collagen deposition accompanying pancreatic cancer, with lymph node metastasis in breast cancer and with regional vessel invasion by giant cell tumor or bone. MMP-9 contributes to the pathogenesis of numerous clinical disease states, including rheumatic arthritis, coronary artery disease, chronic obstructive pulmonary disease, multiple sclerosis, asthma, and cancer. 
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|[https://www.labcorp.com/tests/500124/mmp-9-matrix-metalloproteinase-9 Labcorp]
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|[[Hydroxyproline]]
|Urine
|Hydroxyproline is an amino acid present in appreciable quantities in collagen and excreted in the urine after collagen breakdown. Because urinary hydroxyproline is derived almost entirely from collagen, it reflects the rate of collagen catabolism.
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|[https://www.labcorp.com/tests/700140/amino-acid-profile-quantitative-urine Labcorp], [http://questdiagnostics.com/hcp/intguide/EndoMetab/EndoManual_AtoZ_PDFs/Hydroxyproline_24Hour_Urine.pdf Quest]
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|[[Hydroxyproline]]
|Plasma
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|[https://www.labcorp.com/tests/700068/amino-acid-profile-quantitative-plasma Labcorp], [https://testdirectory.questdiagnostics.com/test/test-detail/37558/hydroxyproline-plasma?cc=MASTER Quest]
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|[[Hydroxylysine]]
|Urine
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|[[Hydroxylysine]]
|Plasma
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== See also ==
* [[Neuroimaging]]
== References ==

Revision as of 17:06, December 24, 2020

There are no established biomarkers for myalgic encephalomyelitis or many of its comorbidities. The following are clinically available lab tests used by some practitioners to aid in differential diagnosis or management of patients’ condition.

Test name Type Description Rationale Relevant diagnoses Commercial availability
Matrix metalloproteinase-9 Serum MMP-9 is a marker of inflammation, tissue remodeling, wound healing, and mobilization of tissue-bound growth factors and cytokines. Its expression correlates with abnormal collagen deposition accompanying pancreatic cancer, with lymph node metastasis in breast cancer and with regional vessel invasion by giant cell tumor or bone. MMP-9 contributes to the pathogenesis of numerous clinical disease states, including rheumatic arthritis, coronary artery disease, chronic obstructive pulmonary disease, multiple sclerosis, asthma, and cancer.  Labcorp
Hydroxyproline Urine Hydroxyproline is an amino acid present in appreciable quantities in collagen and excreted in the urine after collagen breakdown. Because urinary hydroxyproline is derived almost entirely from collagen, it reflects the rate of collagen catabolism. Labcorp, Quest
Hydroxyproline Plasma Labcorp, Quest
Hydroxylysine Urine
Hydroxylysine Plasma

See also[edit | edit source]

References[edit | edit source]