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Lipid raft
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The plasma membranes of cells contain combinations of [[glycosphingolipid]]s and protein receptors organized in glycolipoprotein microdomains termed '''lipid rafts.''' Lipid rafts are disbursed through the [[cell]] [[membrane]] and play important roles in [[protein]] and [[lipid]] transport, as well as cell signaling. A study of patients with [[postural orthostatic tachycardia syndrome]] for autoimmunoreactive IgGs to lipid raft proteins in the heart.<ref>{{Cite journal | date = 2013-07-01 | title = Autoimmunoreactive IgGs against cardiac lipid raft-associated proteins in patients with postural orthostatic tachycardia syndrome|url=https://www.sciencedirect.com/science/article/pii/S1931524413000753|journal=Translational Research|language=en|volume=162|issue=1 | pages = 34β44|doi=10.1016/j.trsl.2013.03.002|issn=1931-5244}}</ref> Patients with [[chronic fatigue syndrome]] were found to have decreased [[Sphingolipid|sphingolipids]] and [[Glycosphingolipid|glycosphingolipids]], building blocks of lipid rafts.<ref>{{Cite journal | last = Naviaux | first = Robert K. | last2 = Naviaux | first2 = Jane C. | last3 = Li | first3 = Kefeng | last4 = Bright | first4 = A. Taylor | last5 = Alaynick | first5 = William A. | last6 = Wang | first6 = Lin | last7 = Baxter | first7 = Asha | last8 = Nathan | first8 = Neil | last9 = Anderson | first9 = Wayne | date = 2016-09-13 | title = Metabolic features of chronic fatigue syndrome|url=http://www.pnas.org/content/113/37/E5472|journal=Proceedings of the National Academy of Sciences|language=en|volume=113|issue=37| pages = E5472βE5480|doi=10.1073/pnas.1607571113|issn=0027-8424|pmid=27573827}}</ref> ==Learn more== *[http://www.meaction.net/2016/08/30/naviauxs-metabolism-paper-is-about-as-big-as-you-think/ Naviaux's metabolism paper is about as big as you think], #[[MEAction]], August 30th 2016 *[[Metabolic features of chronic fatigue syndrome]], Robert Naviaux Study *[https://www.youtube.com/watch?v=SjWnkFpbjgQ III 6 1 Lipid Rafts - youtube] *[https://www.youtube.com/watch?v=pSlgoJxJaR0 Membranes Ch. 2 Lipid Rafts - youtube] *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151114/ Cholesterol, lipid rafts, and disease - The Journal of Clinical Investigaiton] ==See also== *[[Robert Naviaux]] ==References== {{Reflist}} [[Category:Biochemistry and cell biology]] {{Reflist}} [[Category:Lipids]]
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