Lactic acidosis: Difference between revisions
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'''Lactic acidosis''' occurs when too much lactic acid builds up in the bloodstream. Lactic acidosis can be caused by excessive l-lactate (l-lactic acid) or excessive d-lactate ([[d-lactic acid]]). While D-lactic acidosis is less common, increased levels of d-lactic acid and ensuing d-lactic acidosis have been linked to ME/CFS on numerous occasions. | '''Lactic acidosis''' occurs when too much lactic acid builds up in the bloodstream. Lactic acidosis can be caused by excessive l-lactate (l-lactic acid) or excessive d-lactate ([[d-lactic acid]]). While D-lactic acidosis is less common, increased levels of d-lactic acid and ensuing d-lactic acidosis have been linked to ME/CFS on numerous occasions.{{Citation needed|reason=|date=24 August 2020}} | ||
There is also a significant correlation between cognitive dysfunction and neurological impairment symptoms in ME/CFS and those found in patients with d-lactic acidosis.<ref>{{Cite journal|last=Sheedy|first=John R.|last2=Wettenhall|first2=Richard E. H.|last3=Scanlon|first3=Denis|last4=Gooley|first4=Paul R.|last5=Lewis|first5=Donald P.|last6=McGregor|first6=Neil|last7=Stapleton|first7=David I.|last8=Butt|first8=Henry L.|last9= | There is also a significant correlation between cognitive dysfunction and neurological impairment symptoms in ME/CFS and those found in patients with d-lactic acidosis.<ref>{{Cite journal|last=Sheedy|first=John R.|last2=Wettenhall|first2=Richard E. H.|last3=Scanlon|first3=Denis|last4=Gooley|first4=Paul R.|last5=Lewis|first5=Donald P.|last6=McGregor|first6=Neil|last7=Stapleton|first7=David I.|last8=Butt|first8=Henry L.|last9=De Meirleir|first9=Kenny L.|date=Jul 2009|title=Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome|url=https://pubmed.ncbi.nlm.nih.gov/19567398/|journal=In Vivo (Athens, Greece)|volume=23|issue=4|pages=621–628|issn=0258-851X|pmid=19567398|doi=|pmc=|quote=|author-link=|author-link2=|access-date=|author-link3=|author-link4=Paul Gooley|author-link5=Donald Lewis|author-link6=Neil McGregor|via=|author-link7=|author-link8=Henry Butt|author-link9=Kenny De Meirleir}}</ref>{{stub}} | ||
==See also == | ==See also == | ||
Revision as of 13:38, August 24, 2020
Lactic acidosis occurs when too much lactic acid builds up in the bloodstream. Lactic acidosis can be caused by excessive l-lactate (l-lactic acid) or excessive d-lactate (d-lactic acid). While D-lactic acidosis is less common, increased levels of d-lactic acid and ensuing d-lactic acidosis have been linked to ME/CFS on numerous occasions.[citation needed]
There is also a significant correlation between cognitive dysfunction and neurological impairment symptoms in ME/CFS and those found in patients with d-lactic acidosis.[1]
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- ↑ Sheedy, John R.; Wettenhall, Richard E. H.; Scanlon, Denis; Gooley, Paul R.; Lewis, Donald P.; McGregor, Neil; Stapleton, David I.; Butt, Henry L.; De Meirleir, Kenny L. (July 2009). "Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome". In Vivo (Athens, Greece). 23 (4): 621–628. ISSN 0258-851X. PMID 19567398.
