Kynurenine: Difference between revisions

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'''Kynurenine''' is an [[amino acid]] that is produced in the body by [[tryptophan]] metabolism.<ref>{{Cite web|url=https://www.merriam-webster.com/medical/kynurenine|title=Medical Definition of KYNURENINE|website=www.merriam-webster.com|language=en|access-date=2019-11-30}}</ref>
'''Kynurenine''' is an [[amino acid]] that is produced in the body by the metabolism of the essential amino acid [[tryptophan]].<ref>{{Cite web|url=https://www.merriam-webster.com/medical/kynurenine|title=Medical Definition of KYNURENINE|website=www.merriam-webster.com|language=en|access-date=2019-11-30}}</ref><ref>{{Cite web|url=https://pubchem.ncbi.nlm.nih.gov/compound/Kynurenine|title=Kynurenine|last=National Center for Biotechnology Information|first=|authorlink=|last2=|first2=|authorlink2=|date=|website=PubChem Database|language=en|archive-url=|archive-date=|dead-url=|access-date=2020-01-19}}</ref>
 
== ME/CFS ==
The Open Medicine Foundation's [[ME/CFS Severely Ill, Big Data Study|ME/CFS Severely Ill Big Data Study]] found that patients in the study group with severe ME had one of several defects involving the [[Indoleamine 2,3-dioxygenase|IDO2]] gene, which affected tryptophan - kynurenine metabolism. This lead to the [[Metabolic trap|Metabolic Trap]] theory.


==Learn more==
==Learn more==

Revision as of 14:09, January 19, 2020

Kynurenine is an amino acid that is produced in the body by the metabolism of the essential amino acid tryptophan.[1][2]

ME/CFS[edit | edit source]

The Open Medicine Foundation's ME/CFS Severely Ill Big Data Study found that patients in the study group with severe ME had one of several defects involving the IDO2 gene, which affected tryptophan - kynurenine metabolism. This lead to the Metabolic Trap theory.

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. "Medical Definition of KYNURENINE". www.merriam-webster.com. Retrieved November 30, 2019.
  2. National Center for Biotechnology Information. "Kynurenine". PubChem Database. Retrieved January 19, 2020. Cite has empty unknown parameter: |dead-url= (help)