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Kynurenine
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==Uppsala trial, Sweden == In April 2020, the Open Medicine Foundation announced a pilot treatment trial of kynurenine for [[ME/CFS]].<ref name="maymomentum">{{Cite web|url=https://www.omf.ngo/maymomentum/ | title = #May Momentum 2020 | last = Open Medicine Foundation | first = | authorlink = Open Medicine Foundation | date = May 2020 | website = Open Medicine Foundation|language=en-US|archive-url=https://web.archive.org/web/20200621215257/https://www.omf.ngo/maymomentum/|archive-date=2020-06-21|url-status=dead|access-date=2020-05-01}}</ref> Dr [[Jonas Bergquist]] will be running the trial.<ref name="omf-trial-2020">{{Cite web|url=https://www.omf.ngo/2020/04/26/kynurenine-clinical-trial-for-me-cfs/ | title = Kynurenine Clinical Trial for ME / CFS | last = Open Medicine Foundation | first = | authorlink = Open Medicine Foundation | date = 2020-04-26 | website = Open Medicine Foundation|language=en-US|archive-url=|archive-date=|url-status=|access-date=2020-05-05}}</ref> === Trial type === Pilot trial, with cross-over at 3 months. Patients receiving the kynurenine will change to the placebo after 3 months, and patients receiving the placebo will switch to the kynurenine. No control group.<ref name="omf-trial-2020" /> === Aims=== To see whether kynurenine improves [[Cognitive dysfunction|cognitive impairment]] (brain fog), [[Headache|headaches]] and [[Memory problems|memory]] in ME/CFS patients.<ref name="omf-trial-2020" /> === Patients === Only 20 out of a group of 100 ME/CFS patients. Patients will be those identified as having a low level of kynurenine in blood serum and ME/CFS.<ref name="omf-trial-2020" /> === Outcomes === Measurements will be taken from wearable sensors.<ref name="omf-trial-2020" />
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