Interleukin 7 receptor
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
The interleukin 7 receptor is a protein found on the surface of cells. It is made up of two different smaller protein chains - i.e. it is a heterodimer, and consists of two subunits, interleukin 7 receptor-α (CD127) and common-γ chain receptor (CD132). The common-γ chain receptors is shared with various cytokines, including interleukin-2, interleukin 4, interleukin 9, and interleukin 15. Interleukin-7 receptor is expressed on various cell types, including naive and memory T cells and many others.[citation needed]
Function[edit | edit source]
ME/CFS[edit | edit source]
A study by Griffith University found that CD8+ T cells exhibited significantly decreased CD127 and PSGL-1[1]
See also[edit | edit source]
- Advanced glycosylation end-product - AGER gene
- Cytokine
Learn more[edit | edit source]
- CD8, Wikipedia
References[edit | edit source]
- ↑ Brenu, Ekua W.; Broadley, Simon; Nguyen, Thao; Johnston, Samantha; Ramos, Sandra; Staines, Don; Marshall-Gradisnik, Sonya (January 4, 2016). "A Preliminary Comparative Assessment of the Role of CD8+ T Cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Multiple Sclerosis". Journal of Immunology Research. 2016: e9064529. doi:10.1155/2016/9064529. ISSN 2314-8861.
