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Interleukin 7 receptor
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The '''[[interleukin 7]] receptor''' is a protein found on the surface of cells. It is made up of two different smaller [[:Category:Proteins|protein]] chains - i.e. it is a heterodimer, and consists of two subunits, interleukin 7 receptor-Ξ± ([[CD127]]) and common-Ξ³ chain receptor ([[CD132]]). The common-Ξ³ chain receptors is shared with various cytokines, including [[Interleukin 2|interleukin-2]], [[interleukin 4]], [[interleukin 9]], and [[interleukin 15]]. Interleukin-7 receptor is expressed on various cell types, including naive and memory [[T cell|T cells]] and many others.{{Citation needed | date = 2022}} ==Function== ==ME/CFS== A study by [[Griffith University]] found that [[Cytotoxic T cell|CD8+ T cells]] exhibited significantly decreased [[CD127]] and [[PSGL-1]]<ref name="Brenu2016">{{Cite journal | title = A Preliminary Comparative Assessment of the Role of CD8+ T Cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Multiple Sclerosis| date = 2016-01-04 | url = https://www.hindawi.com/journals/jir/2016/9064529/|journal=Journal of Immunology Research|volume=2016|issue=|pages=e9064529 | last =Brenu | first =Ekua W. | author-link = Ekua Brenu | last2=Broadley | first2 = Simon | author-link2 = | last3 = Nguyen | first3 = Thao | author-link3 = | last4 = Johnston | first4 = Samantha | author-link4 = | last5 = Ramos | first5 = Sandra | author-link5 = | last6 = Staines | first6 = Don | author-link6 = Donald Staines | last7 = Marshall-Gradisnik | first7 = Sonya | author-link7 = Sonya Marshall-Gradisnik | last8 = | first8 = | last9 = | first9 = |language=en|doi=10.1155/2016/9064529|pmc=|pmid=|access-date=|issn=2314-8861|quote=|via=}}</ref> == See also == * [[Advanced glycosylation end-product]] - AGER gene * [[Cytokine]] ==Learn more== *[https://en.wikipedia.org/wiki/CD8 CD8], Wikipedia ==References== {{Reflist}} [[Category:Body systems]] [[Category:Immunology]]
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