Indoleamine-2,3-dioxygenase 2: Difference between revisions

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==ME/CFS==
==ME/CFS==
The [[ME/CFS Severely Ill, Big Data Study|ME/CFS Severely Ill Big Data Project]] analyzed genes of 20 patients who were severely ill with ME and CFS, and identified several different genetic defects in the genes encoding the '''IDO2''' enzyme.
The [[ME/CFS Severely Ill, Big Data Study|ME/CFS Severely Ill Big Data Project]] analyzed genes of 20 patients who were severely ill with ME and CFS, and identified several different genetic defects in the genes encoding the '''IDO2''' [[enzyme]].
 
== Notable studies and publications ==
* 2019, The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS<ref name="Phair2019">{{Cite journal|last=Phair|first=Robert D.|author-link=Robert Phair|last2=Davis|first2=Ronald W.|author-link2=Ron Davis|last3=Kashi|first3=Alex A.|author-link3=Alex Kashi|author-link4=|author-link5=|author-link6=|date=2019|title=The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS|url=https://www.mdpi.com/2075-4418/9/3/82|journal=Diagnostics|language=en|volume=9|issue=3|pages=82|doi=10.3390/diagnostics9030082|quote=|via=}}</ref> [https://www.mdpi.com/2075-4418/9/3/82/htm (Full text)]


==See also==
==See also==

Revision as of 18:24, January 19, 2020

Indoleamine-2,3-dioxygenase 2 is more commonly known as IDO2 is an enzyme in the kynurenine pathway involved in the metabolism of the essential amino acid tryptophan.[1] The gene encoding IDO2 is also sometimes referred to as IDO2.[citation needed]

Function[edit | edit source]

ME/CFS[edit | edit source]

The ME/CFS Severely Ill Big Data Project analyzed genes of 20 patients who were severely ill with ME and CFS, and identified several different genetic defects in the genes encoding the IDO2 enzyme.

Notable studies and publications[edit | edit source]

  • 2019, The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS[2] (Full text)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. Ball, Helen J.; Yuasa, Hajime J.; Austin, Christopher J. D.; Weiser, Silvia; Hunt, Nicholas H. (March 1, 2009). "Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway". The International Journal of Biochemistry & Cell Biology. 41 (3): 467–471. doi:10.1016/j.biocel.2008.01.005. ISSN 1357-2725.
  2. Phair, Robert D.; Davis, Ronald W.; Kashi, Alex A. (2019). "The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS". Diagnostics. 9 (3): 82. doi:10.3390/diagnostics9030082.