Indoleamine-2,3-dioxygenase 2: Difference between revisions
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Notjusttired (talk | contribs) (create stub) |
Notjusttired (talk | contribs) m (expand ref, fix kynurenine typo, fix links) |
||
| Line 1: | Line 1: | ||
{{stub}} | {{stub}} | ||
'''Indoleamine-2,3-dioxygenase 2''' is more commonly known as ''IDO2'' is an [[enzyme]] in the [[kynurenine pathway]] involved in the metabolism of the essential amino acid [[tryptophan]].<ref name="Ball2009"> | '''Indoleamine-2,3-dioxygenase 2''' is more commonly known as '''IDO2''' is an [[enzyme]] in the [[kynurenine pathway]] involved in the metabolism of the essential amino acid [[tryptophan]].<ref name="Ball2009">{{Cite journal|last=Ball|first=Helen J.|last2=Yuasa|first2=Hajime J.|last3=Austin|first3=Christopher J. D.|last4=Weiser|first4=Silvia|last5=Hunt|first5=Nicholas H.|date=2009-03-01|title=Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway|url=http://www.sciencedirect.com/science/article/pii/S1357272508000095|journal=The International Journal of Biochemistry & Cell Biology|volume=41|issue=3|pages=467–471|doi=10.1016/j.biocel.2008.01.005|issn=1357-2725}}</ref> The gene encoding IDO2 is also sometimes referred to as IDO2.{{Citation needed|reason=|date=19 January 2020}} | ||
==Function== | ==Function== | ||
==ME/CFS== | ==ME/CFS== | ||
The [[ME/CFS Severely Ill Big Data Project]] analyzed genes of 20 patients who were severely ill with ME and CFS, and identified several different genetic defects in the [[IDO2]] genes. | The [[ME/CFS Severely Ill, Big Data Study|ME/CFS Severely Ill Big Data Project]] analyzed genes of 20 patients who were severely ill with ME and CFS, and identified several different genetic defects in the [[IDO2]] genes. | ||
==See also== | ==See also== | ||
| Line 11: | Line 11: | ||
* [[Kynurenine pathway]] | * [[Kynurenine pathway]] | ||
* [[tryptophan]] | * [[tryptophan]] | ||
* [[ | * [[kynurenine]] | ||
==Learn more== | ==Learn more== | ||
Revision as of 18:16, January 19, 2020
 | This article is a stub. |
Indoleamine-2,3-dioxygenase 2 is more commonly known as IDO2 is an enzyme in the kynurenine pathway involved in the metabolism of the essential amino acid tryptophan.[1] The gene encoding IDO2 is also sometimes referred to as IDO2.[citation needed]
Function[edit | edit source]
ME/CFS[edit | edit source]
The ME/CFS Severely Ill Big Data Project analyzed genes of 20 patients who were severely ill with ME and CFS, and identified several different genetic defects in the IDO2 genes.
See also[edit | edit source]
Learn more[edit | edit source]
References[edit | edit source]
- ↑ Ball, Helen J.; Yuasa, Hajime J.; Austin, Christopher J. D.; Weiser, Silvia; Hunt, Nicholas H. (March 1, 2009). "Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway". The International Journal of Biochemistry & Cell Biology. 41 (3): 467–471. doi:10.1016/j.biocel.2008.01.005. ISSN 1357-2725.
