Immunoglobulin M

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Immunoglobulin M or IgM is a basic antibody that is produced by B cells.[1]

Function[edit | edit source]

ME/CFS[edit | edit source]

One study found elevated blood serum concentrations of both IgA and IgM to lipopolysaccharides of gram-negative bacteria. Serum IgA levels correlated with illness severity as measured by the FibroFatigue scale.[2]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. Betts, JG; Young, KA; Wise, JA; Johnson, E; Poe, B; Kruse, DH; Korol, O; Johnson, JE; Womble, M; DeSaix, P (April 23, 2013). "Key Terms". Anatomy and Physiology. OpenStax. Houston, Texas. Retrieved October 20, 2021.
  2. Maes, Michael; Mihaylova, Ivana; Leunis, Jean-Claude (April 2007). "Increased serum IgA and IgM against LPS of enterobacteria in chronic fatigue syndrome (CFS): indication for the involvement of gram-negative enterobacteria in the etiology of CFS and for the presence of an increased gut-intestinal permeability". Journal of Affective Disorders. 99 (1–3): 237–240. doi:10.1016/j.jad.2006.08.021. ISSN 0165-0327. PMID 17007934.