Hepatitis C: Difference between revisions

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'''Hepatitis C''' ('''HCV''' or '''Hep C''') is a disease caused by an [[RNA]] [[virus]] that affects approximately 170 million people worldwide<ref name="Siu2016" /> and is most often known for its associations with liver damage.
'''Hepatitis C''' ('''HCV''' or '''Hep C''') is a disease caused by an [[RNA]] [[virus]] that affects approximately 170 million people worldwide<ref name="Siu2016">{{citation
| last1  = Siu      | first1 = Gavin Ka Yu        | authorlink1 =
| last2  = Zhou    | first2 = Fan                | authorlink2 =
| last3  = Yu      | first3 = Mei Kuen            | authorlink3 =
| last4  = Zhang    | first4 = Leiliang            | authorlink4 =
| last5  = Wang    | first5 = Tuanlao            | authorlink5 =
| last6  = Liang    | first6 = Yongheng            | authorlink6 =
| last7  = Chen    | first7 = Yangchao            | authorlink7 =
| last8  = Chan    | first8 = Hsiao Chang        | authorlink8 =
| last9  = Yu      | first9 = Sidney              | authorlink9 =
| title  = Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation
| journal = Scientific Reports 6 | year = 2016 |
| doi    = 10.1038/srep23464
| url    = http://www.nature.com/articles/srep23464
}}</ref> and is most often known for its associations with liver damage.<ref name="WHO2015">{{citation|title=Hepatitis C  Fact sheet N°164|url=http://www.who.int/mediacentre/factsheets/fs164/en/|website=WHO|accessdate=4 February 2016|date=July 2015}}</ref>


Hepatitis C incidence has been shown to be increased in [[chronic fatigue syndrome]] patients.
Hepatitis C incidence has been shown to be increased in [[chronic fatigue syndrome]] patients.{{citation needed|date=Jul 2020}}


==Prevalence==
==Prevalence==
It is estimated that between 130-200 million people worldwide have a hepatitis C infection, occurring most commonly in Africa and Central and East Asia.<ref name="WHO2015" /> In 2013, hepatitis C was the cause of around 358,000 deaths due to cirrhosis and 343,000 deaths due to liver cancer.<ref name="GBD204" />
It is estimated that between 130-200 million people worldwide have a hepatitis C infection, occurring most commonly in Africa and Central and East Asia.<ref name="WHO2015" /> In 2013, hepatitis C was the cause of around 358,000 deaths due to cirrhosis and 343,000 deaths due to liver cancer.<ref name="GBD204">{{citation|last1=GBD 2013 Mortality and Causes of Death|first1=Collaborators|title=Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013.|journal=Lancet|date=17 December 2014|pmid=25530442|doi=10.1016/S0140-6736(14)61682-2|volume=385|issue=9963|pages=117–71|pmc=4340604}}</ref>


==Transmission==
==Transmission==
Line 13: Line 27:


==Hepatitis C in Chronic Fatigue Syndrome==
==Hepatitis C in Chronic Fatigue Syndrome==
==Notable studies==
==Notable studies==


Line 18: Line 33:


==Learn more==
==Learn more==
*[https://en.wikipedia.org/wiki/Hepatitis_C Wikipedia - Hepatitis C]
*[http://www.who.int/mediacentre/factsheets/fs164/en/ Factsheet] - World Health Organization
 
Hepatitis C is considered a global health problem <ref name="GBD204">{{citation|last1=GBD 2013 Mortality and Causes of Death|first1=Collaborators|title=Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013.|journal=Lancet|date=17 December 2014|pmid=25530442|doi=10.1016/S0140-6736(14)61682-2|volume=385|issue=9963|pages=117–71|pmc=4340604}}</ref>


==See also==
==See also==
==Learn more==
*2016, [http://www.nature.com/articles/srep23464 Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation]<ref name="Siu2016">{{citation
| last1  = Siu      | first1 = Gavin Ka Yu        | authorlink1 =
| last2  = Zhou    | first2 = Fan                | authorlink2 =
| last3  = Yu      | first3 = Mei Kuen            | authorlink3 =
| last4  = Zhang    | first4 = Leiliang            | authorlink4 =
| last5  = Wang    | first5 = Tuanlao            | authorlink5 =
| last6  = Liang    | first6 = Yongheng            | authorlink6 =
| last7  = Chen    | first7 = Yangchao            | authorlink7 =
| last8  = Chan    | first8 = Hsiao Chang        | authorlink8 =
| last9  = Yu      | first9 = Sidney              | authorlink9 =
| title  = Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation
| journal = Scientific Reports 6 | year = 2016 |
| doi    = 10.1038/srep23464
| url    = http://www.nature.com/articles/srep23464
}}</ref>
*[http://www.who.int/mediacentre/factsheets/fs164/en/ Factsheet]<ref name="WHO2015">{{citation|title=Hepatitis C  Fact sheet N°164|url=http://www.who.int/mediacentre/factsheets/fs164/en/|website=WHO|accessdate=4 February 2016|date=July 2015}}</ref> - World Health Organization


==References==
==References==

Revision as of 22:41, July 31, 2020

Hepatitis C (HCV or Hep C) is a disease caused by an RNA virus that affects approximately 170 million people worldwide[1] and is most often known for its associations with liver damage.[2]

Hepatitis C incidence has been shown to be increased in chronic fatigue syndrome patients.[citation needed]

Prevalence[edit | edit source]

It is estimated that between 130-200 million people worldwide have a hepatitis C infection, occurring most commonly in Africa and Central and East Asia.[2] In 2013, hepatitis C was the cause of around 358,000 deaths due to cirrhosis and 343,000 deaths due to liver cancer.[3]

Transmission[edit | edit source]

Signs and symptoms[edit | edit source]

Diagnosis[edit | edit source]

Hepatitis C in Chronic Fatigue Syndrome[edit | edit source]

Notable studies[edit | edit source]

Potential treatments[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. Siu, Gavin Ka Yu; Zhou, Fan; Yu, Mei Kuen; Zhang, Leiliang; Wang, Tuanlao; Liang, Yongheng; Chen, Yangchao; Chan, Hsiao Chang; Yu, Sidney (2016), "Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation", Scientific Reports 6, doi:10.1038/srep23464 Cite has empty unknown parameter: |1= (help)
  2. 2.0 2.1 "Hepatitis C Fact sheet N°164", WHO, July 2015, retrieved February 4, 2016
  3. GBD 2013 Mortality and Causes of Death, Collaborators (December 17, 2014), "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013.", Lancet, 385 (9963): 117–71, doi:10.1016/S0140-6736(14)61682-2, PMC 4340604, PMID 25530442