Hepatitis C: Difference between revisions

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'''Hepatitis C''' ('''HCV''' or '''Hep C''') is a disease caused by an [[RNA]] [[virus]] that affects approximately 170 million people worldwide<ref name="Siu2016">{{citation
'''Hepatitis C''' ('''HCV''' or '''Hep C''') is a disease caused by an [[RNA]] [[virus]] that affects approximately 170 million people worldwide<ref name="Siu2016">{{citation | last1 = Siu | first1 = Gavin Ka Yu | authorlink1 = | last2 = Zhou | first2 = Fan | authorlink2 = | last3 = Yu | first3 = Mei Kuen | authorlink3 = | last4 = Zhang | first4 = Leiliang | author-link4 = | last5 = Wang | first5 = Tuanlao| authorlink5 = | last6 = Liang | first6 = Yongheng | author-link6 = | last7 = Chen | first7 = Yangchao| authorlink7 = | last8 = Chan | first8 = Hsiao Chang | authorlink8 = | last9 =Yu | first9 = Sidney | author-link9 = | title = Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation | journal = Scientific Reports 6 | year = 2016 | doi = 10.1038/srep23464 | url = http://www.nature.com/articles/srep23464 }}</ref> and is most often known for its associations with liver damage.<ref name="WHO2015">{{citation | title=Hepatitis C  Fact sheet N°164 | url = http://www.who.int/mediacentre/factsheets/fs164/en/|website=WHO|access-date=4 February 2016 | date = July 2015}}</ref>
| last1   = Siu     | first1 = Gavin Ka Yu         | authorlink1 =  
| last2   = Zhou     | first2 = Fan                 | authorlink2 =  
| last3   = Yu       | first3 = Mei Kuen           | authorlink3 =  
| last4   = Zhang   | first4 = Leiliang           | authorlink4 =  
| last5   = Wang     | first5 = Tuanlao             | authorlink5 =  
| last6   = Liang   | first6 = Yongheng           | authorlink6 =  
| last7   = Chen     | first7 = Yangchao           | authorlink7 =  
| last8   = Chan     | first8 = Hsiao Chang         | authorlink8 =  
| last9   = Yu       | first9 = Sidney             | authorlink9 =  
| title   = Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation
| journal = Scientific Reports 6 | year = 2016 |
| doi     = 10.1038/srep23464
| url     = http://www.nature.com/articles/srep23464
}}</ref> and is most often known for its associations with liver damage.<ref name="WHO2015">{{citation|title=Hepatitis C  Fact sheet N°164|url=http://www.who.int/mediacentre/factsheets/fs164/en/|website=WHO|accessdate=4 February 2016|date=July 2015}}</ref>


Hepatitis C incidence has been shown to be increased in [[chronic fatigue syndrome]] patients.{{citation needed|date=Jul 2020}}
Hepatitis C incidence has been shown to be increased in [[chronic fatigue syndrome]] patients.{{citation needed | date = Jul 2020}}


==Prevalence==
==Prevalence==
It is estimated that between 130-200 million people worldwide have a hepatitis C infection, occurring most commonly in Africa and Central and East Asia.<ref name="WHO2015" /> In 2013, hepatitis C was the cause of around 358,000 deaths due to cirrhosis and 343,000 deaths due to liver cancer.<ref name="GBD204">{{citation|last1=GBD 2013 Mortality and Causes of Death|first1=Collaborators|title=Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013.|journal=Lancet|date=17 December 2014|pmid=25530442|doi=10.1016/S0140-6736(14)61682-2|volume=385|issue=9963|pages=117–71|pmc=4340604}}</ref>
It is estimated that between 130-200 million people worldwide have a hepatitis C infection, occurring most commonly in Africa and Central and East Asia.<ref name="WHO2015" /> In 2013, hepatitis C was the cause of around 358,000 deaths due to cirrhosis and 343,000 deaths due to liver cancer.<ref name="GBD204">{{citation | last1 = GBD 2013 Mortality and Causes of Death | first1 = Collaborators | title = Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013.|journal=Lancet | date = 17 December 2014|pmid=25530442|doi=10.1016/S0140-6736(14)61682-2|volume=385|issue=9963|pages=117–71|pmc=4340604}}</ref>


==Transmission==
==Transmission==
Line 32: Line 18:
==Potential treatments==
==Potential treatments==


==Learn more==
== See also ==
 
== Learn more ==
*[http://www.who.int/mediacentre/factsheets/fs164/en/ Factsheet] - World Health Organization
*[http://www.who.int/mediacentre/factsheets/fs164/en/ Factsheet] - World Health Organization


==See also==
== References ==
 
==References==
{{Reflist}}
{{Reflist}}



Latest revision as of 01:47, April 2, 2023

Hepatitis C (HCV or Hep C) is a disease caused by an RNA virus that affects approximately 170 million people worldwide[1] and is most often known for its associations with liver damage.[2]

Hepatitis C incidence has been shown to be increased in chronic fatigue syndrome patients.[citation needed]

Prevalence[edit | edit source]

It is estimated that between 130-200 million people worldwide have a hepatitis C infection, occurring most commonly in Africa and Central and East Asia.[2] In 2013, hepatitis C was the cause of around 358,000 deaths due to cirrhosis and 343,000 deaths due to liver cancer.[3]

Transmission[edit | edit source]

Signs and symptoms[edit | edit source]

Diagnosis[edit | edit source]

Hepatitis C in Chronic Fatigue Syndrome[edit | edit source]

Notable studies[edit | edit source]

Potential treatments[edit | edit source]

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. Siu, Gavin Ka Yu; Zhou, Fan; Yu, Mei Kuen; Zhang, Leiliang; Wang, Tuanlao; Liang, Yongheng; Chen, Yangchao; Chan, Hsiao Chang; Yu, Sidney (2016), "Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation", Scientific Reports 6, doi:10.1038/srep23464
  2. 2.0 2.1 "Hepatitis C Fact sheet N°164", WHO, July 2015, retrieved February 4, 2016
  3. GBD 2013 Mortality and Causes of Death, Collaborators (December 17, 2014), "Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013.", Lancet, 385 (9963): 117–71, doi:10.1016/S0140-6736(14)61682-2, PMC 4340604, PMID 25530442