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Hair loss
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'''Hair loss''' is a symptom that occurs occasionally in [[ME/CFS]].<ref name="Verrillo1" /> <ref name="canadianconsensus-CCC" /> It can also be a symptom of comorbid illnesses such as [[Thyroid disease|hypothyroidism]], [[systemic lupus erythematosus]] and is sometimes found in [[Long COVID]] patients.<ref name="hussain2021" /> Hair loss can refer to either a hair loss condition such as '''alopecia areata''', where patches of scalp lose all or virtually all hair, or as '''telogen effluvium''', which is a general thinning of hair across the head where hair loss is typically less than 50% of hair.<ref name="PMC7753411">{{Cite journal | title = Telogen effluvium: a sequela of COVID‐19 | date = 2020-11-23| url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753411/|journal=International Journal of Dermatology | pages = 10.1111/ijd.15313 | last = Mieczkowska | first = Karolina | last2 = Deutsch | first2 = Alana | last3 = Borok | first3 = Jenna | last4 = Guzman | first4 = Anthony K. | last5 = Fruchter | first5 = Renee | last6 = Patel | first6 = Parth | last7 = Wind | first7 = Olivia | last8 = McLellan | first8 = Beth N. | last9 = Mann | first9 = Ranon E. | last10 = Halverstam | first10 = Caroline P.|doi=10.1111/ijd.15313|pmc=7753411|pmid=33226117|issn=0011-9059}}</ref><ref name="hussain2021">{{Cite journal | title = A systematic review of acute telogen effluvium, a harrowing post-COVID-19 manifestation | date = 2022 | url=https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.27534|journal=Journal of Medical Virology|volume=94|issue=4 | pages = 1391–1401 | last = Hussain | first = Nabeel | last2 = Agarwala | first2 = Preeti | last3 = Iqbal | first3 = Kinza | last4 = Omar | first4 = Hanaa Mohamed Sheikh | last5 = Jangid | first5 = Gurusha | last6 = Patel | first6 = Vraj | last7 = Rathore | first7 = Sawai Singh | last8 = Kumari | first8 = Chandani | last9 = Velasquez-Botero | first9 = Felipe | last10 = López | first10 = Guadalupe Abigail Benítez | last11 = Vishwakarma | first11 = Yogesh|language=en|doi=10.1002/jmv.27534|issn=1096-9071}}</ref><ref name=":0">{{Cite web | url=https://www.webmd.com/connect-to-care/hair-loss/what-causes-telogen-effluvium | title = What Causes Telogen Effluvium?|website=WebMD|language=en|access-date=2022-02-20}}</ref> ==Prevalence== The [[Canadian Consensus Criteria]] recognizes hair loss as a ''neuroendocrine system'' symptom in [[ME/CFS]].<ref name="canadianconsensus-CCC">{{Citation | last1 = Carruthers | first1 = Bruce M. | authorlink1 = Bruce Carruthers | last2 = Jain | first2 = Anil Kumar | authorlink2 = Anil Kumar Jain | last3 = De Meirleir | first3 = Kenny L. | authorlink3 = Kenny De Meirleir | last4 = Peterson | first4 = Daniel L. | authorlink4 = Daniel Peterson | last5 = Klimas | first5 = Nancy G. | authorlink5 = Nancy Klimas | last6 = Lerner | first6 = A. Martin | authorlink6 = Martin Lerner | last7 = Bested | first7 = Alison C. | authorlink7 = Alison Bested | last8 = Flor-Henry | first8 = Pierre | author-link8 = Pierre Flor-Henry | last9 = Joshi | first9 = Pradip | author-link9 = Pradip Joshi | last10 = Powles | first10 = AC Peter | authorlink10 = A C Peter Powles | last11 = Sherkey | first11 = Jeffrey A. | authorlink11 = Jeffrey Sherkey | last12 = van de Sande | first12 = Marjorie I. | authorlink12 = Marjorie van de Sande | title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols| journal = Journal of Chronic Fatigue Syndrome | volume = 11 | issue = 2 | pages = 7-115 | date = 2003 | pmid = | doi = 10.1300/J092v11n01_02| url = http://www.investinme.org/Documents/PDFdocuments/CanadianDefinitionME-CFS.pdf}}</ref> [[Katrina Berne]] reports a prevalence of 20-35% for hair loss.<ref>{{citation | last = Berne | first = Katrina | date = Dec 1, 1995 | title = Running on Empty: The Complete Guide to Chronic Fatigue Syndrome (CFIDS)| edition =2nd |url= https://www.amazon.co.uk/Running-Empty-Complete-Chronic-Syndrome/dp/0897931912/ | publisher = Hunter House | page = 58 |isbn= 978-0897931915}}</ref> ==Potential causes== *[[Endocrine system |Endocrine]] changes *Medication side effecta (e.g. [[DHEA]], [[Ampligen]], [[Elmiron]]) *[[Lysine]] deficiency *Excessive [[Vitamin A]] intake *Excessive [[selenium]] intake *Increase in [[stress]] hormones<ref name="Verrillo1" /> *Any serious illness can cause telogen effluvium, including COVID-19 and ME/CFS<ref name=":0" /><ref name="canadianconsensus-CCC" /><ref name="hussain2021" /> ==Potential treatments== *Treatment of comorbid illnesses such as [[Thyroid disease|hypothyroidism]] or [[systemic lupus erythematosus]]<ref name=":0" /> *Avoidance of harsh hair products *[[B vitamin]]s *[[Coenzyme Q10]] *[[Ginkgo biloba]] *[[Inositol]]<ref name="Verrillo1">{{Cite book | last = Verrillo | first = Erica | authorlink = Erica Verrillo | title = Chronic Fatigue Syndrome: A Treatment Guide | edition= 2nd | type = Kindle eBook | date = September 14, 2012 | url = http://www.cfstreatmentguide.com/ }}</ref><ref>{{Cite web | url=https://www.nhs.uk/conditions/hair-loss/ | title = Hair loss | last = | first = | authorlink = | date = 2017-10-23 | website = National Health Service|language=en|archive-url=|archive-date=|url-status=|access-date=2022-02-20}}</ref> ==Learn more== *[https://www.aad.org/public/diseases/hair-loss/types/alopecia/symptoms Alopecia areata - symptoms] *[https://www.nhs.uk/conditions/hair-loss/ Hair loss] - NHS *[https://www.mayoclinic.org/diseases-conditions/hair-loss/symptoms-causes/syc-20372926 Hair loss symptoms and causes] - Mayo Clinic *[https://www.webmd.com/skin-problems-and-treatments/hair-loss/understanding-hair-loss-basics Understanding Hair Loss: Basics] - WebMD *[https://www.webmd.com/connect-to-care/hair-loss/what-causes-telogen-effluvium What causes Telogen Effluvium] - WebMD ==See also== * [[Biotin]] ==References== {{Reflist}} [[Category:Signs and symptoms]] [[Category:Endocrine signs and symptoms]] [[Category:Long COVID signs and symptoms]]
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