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Graded exercise therapy
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==Fear of exercise== The [[PACE Trial Management Group|PACE trial investigators]] have stated that they believe a significant maintaining factor in the persistence of ME/CFS is fear of [[exercise]].<ref>{{Cite journal | last = Torjesen | first = Ingrid | date = 2015-10-28 | title = Tackling fear about exercise produces long term benefit in chronic fatigue syndrome| url = https://www.bmj.com/content/351/bmj.h5771|journal=BMJ|language=en|volume=351 | pages = h5771|doi=10.1136/bmj.h5771|issn=1756-1833|pmid=26511755}}</ref> This claim has been criticized as unsupported by trial results.<ref>{{Cite journal | date = 2018-10-13 | title = Objective measures found a lack of improvement for CBT & GET in the PACE Trial: subjective improvements may simply represent response biases or placebo effects in this non-blinded trial| url = https://www.bmj.com/content/350/bmj.h227/rr-10|journal=The BMJ|language=en}}</ref> A study by [[Jo Nijs|Nijs]] et al. in 2004 concluded: {{Quote box|quote=These results indicate a lack of correlation between kinesiophobia and exercise capacity, activity limitations, or participation restrictions, at least in patients with [[chronic fatigue syndrome |CFS]] who are experiencing widespread [[myalgia |muscle]] or [[arthralgia |joint pain]]. | title = Chronic Fatigue Syndrome: Lack of Association between Pain-Related Fear of Movement and Exercise Capacity and Disability|source=Jo Nij, Katrien Vanherberghen, William Duquet & Kenny De Meirleir (2004)}}
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