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==Notable studies in ME/CFS== *2008, Evidence of inflammatory immune signaling in chronic fatigue syndrome: A pilot study of [[gene expression]] in peripheral blood.<ref name="Aspler, 2008" /> [http://psycnet.apa.org/record/2008-15631-001 (Abstract)] *2008, Neuroendocrine and immune network remodeling in chronic fatigue syndrome: an exploratory analysis<ref name="Fuite, 2010" /> [https://www.sciencedirect.com/science/article/pii/S0888754308001948?via%3Dihub (Full Text)] *2010, [[Biomarker]]s in Chronic Fatigue Syndrome: Evaluation of [[NKC|Natural Killer Cell]] Function and Dipeptidyl Peptidase IV/CD26<ref>{{Cite journal | last = Fletcher | first = Mary A. | authorlink = Mary Ann Fletcher | last2 = Zeng | first2 = Xiao R. | authorlink2 = | last3 = Maher | first3 = Kevin | authorlink3 = | last4 = Levis | first4 = Silvina | authorlink4 = | last5 = Hurwitz | first5 = Barry | authorlink5 = | last6 = Antoni | first6 = Michael | authorlink6 = Michael Antoni | last7 = Broderick | first7 = Gordon | authorlink7 = Gordon Broderick | last8 = Klimas | first8 = Nancy G. | author-link8 = Nancy Klimas | date = 2010-05-25|editor-last = Unutmaz|editor-first = Derya | title = Biomarkers in Chronic Fatigue Syndrome: Evaluation of Natural Killer Cell Function and Dipeptidyl Peptidase IV/CD26| url = https://dx.plos.org/10.1371/journal.pone.0010817|journal=PLoS ONE|language=en|volume=5|issue=5| pages = e10817|doi=10.1371/journal.pone.0010817|issn=1932-6203|pmc=2876037|pmid=20520837|access-date=|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876037/ (Full Text)] *2010, A Formal Analysis of Cytokine Networks in Chronic Fatigue Syndrome<ref name="Broderick, 2010" /> *2010, [[Cytokines]] across the night in chronic fatigue syndrome with and without [[fibromyalgia]]<ref name="Nakamura, 2010" /> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849324/ (Full Text)] *2010, Plasma neuropeptide Y: a biomarker for symptom severity in chronic fatigue syndrome<ref>{{Citation | last1 = Fletcher | first1 = Mary Ann | authorlink = Mary Ann Fletcher | last2 = Rosenthal | first2 = Martin | last3 = Antoni | first3 = Michael | authorlink3 =Michael Antoni | last4 = Ironson | first4 = Gail | last5 = Zeng | first5 = Xiao R | last6 = Barnes | first6 = Zachary | authorlink6 = Zachary Barnes | last7 = Harvey | first7 = Jeanna M | authorlink7 = Jeanna Harvey | last8 = Hurwitz | first8 = Barry | last9 = Levis | first9 = Silvina | last10 = Broderick | first10 = Gordon | authorlink10=Gordon Broderick | last11 = Klimas | first11 = Nancy G | authorlink11 = Nancy Klimas | title = Plasma neuropeptide Y: a biomarker for symptom severity in chronic fatigue syndrome|journal = Behavioral and Brain Functions| volume = 6 | issue = 76| page = | date = 2010|doi= 10.1186/1744-9081-6-76}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024290/ (Full Text)] *2011, Myalgic encephalomyelitis: International Consensus Criteria<ref>{{Cite journal | last = Carruthers | first = Bruce M. | authorlink = Bruce Carruthers | last2 = van de Sande | first2 = Marjorie I. | authorlink2 = Marjorie van de Sande | last3 = De Meirleir | first3 = Kenny L. | authorlink3=Kenny De Meirleir | last4 = Klimas | first4 = Nancy G. | author-link4 = Nancy Klimas | last5 = Broderick | first5 = Gordon | authorlink5 = Gordon Broderick | last6 = Mitchell | first6 = Terry | authorlink6 = Terry Mitchell | last7 = Staines | first7 = Donald | author-link7 = Donald Staines | last8 = Powles | first8 = A.C. Peter | author-link8 = A C Peter Powles | last9 = Speight | first9 = Nigel | author-link9 = Nigel Speight | last10 = Vallings | first10 = Rosamund | authorlink10 = Rosamund Vallings | last11 = Bateman | first11 = Lucinda | authorlink11 = Lucinda Bateman | last12 = Baumgarten-Austrheim | first12 = Barbara | authorlink12 = Barbara Baumgarten-Austrheim | last13 = Bell | first13 = David | author-link13 = David Bell | last14 = Carlo-Stella | first14 = Nicoletta | authorlink14 = Nicoletta Carlo-Stella | last15 = Chia | first15 = John | authorlink15 = John Chia | last16 = Darragh | first16 = Austin | authorlink16 = Austin Darragh | last17 = Jo | first17 = Daehyun | authorlink17 = Daehyun Jo | last18 = Lewis | first18 = Donald | author-link18 = Donald Lewis | last19 = Light | first19 = Alan | author-link19 = Alan Light | last20 = Marshall-Gradisnik | first20 = Sonya | author-link20 = Sonya Marshall-Gradisnik | last21 = Mena | first21 = Ismael | author-link21 = Ismael Mena | last22 = Mikovits | first22 = Judy | author-link22 = Judy Mikovits | last23 = Miwa | first23 = Kunihisa | author-link23 = Kunihisa Miwa | last24 = Murovska | first24 = Modra | author-link24 = Modra Murovska | last25 = Pall | first25 = Martin | author-link25 = Martin Pall | last26 = Stevens | first26 = Staci | author-link26 = Staci Stevens | date = 2011-08-22 | title=Myalgic encephalomyelitis: International Consensus Criteria| url = https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2796.2011.02428.x|journal=Journal of Internal Medicine|language=en|volume=270|issue=4 | pages = 327β338|doi=10.1111/j.1365-2796.2011.02428.x|issn=0954-6820|pmc=3427890|pmid=21777306|via=}}</ref> *2012, Biomarkers for chronic fatigue.<ref name="Klimas, 2012" /> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373648/ (Full Text)] *2012, Cytokine expression profiles of immune imbalance in post-[[mononucleosis]] chronic fatigue<ref name="Broderick, 2012" /> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480896/ (Full Text)] *2014, A Role for Homeostatic Drive in the Perpetuation of Complex Chronic Illness: [[Gulf War Illness]] and Chronic Fatigue Syndrome<ref>{{Citation | last1 = Craddock | first1 = Travis J.A. | authorlink1 = Travis Craddock | last2 = Fritsch | first2 = Paul | authorlink2 = | last3 = Rice, Jr | first3 = Mark A. | authorlink3 = | last4 = del Rosario | first4 = Ryan M. | authorlink4 = | last5 = Miller | first5 = Diane B. | authorlink5 = | last6 = Fletcher | first6 = Mary Ann | authorlink6 = Mary Ann Fletcher | last7 = Klimas | first7 = Nancy G. | authorlink7 = Nancy Klimas | last8 = Broderick | first8 = Gordon | author-link8 = Gordon Broderick | title = A Role for Homeostatic Drive in the Perpetuation of Complex Chronic Illness: Gulf War Illness and Chronic Fatigue Syndrome | journal = PLOS One | volume = 9 | issue = 1 | page = e84839 | date = 2014 | pmid = | doi = 10.1371/journal.pone.0084839 }}</ref> [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084839 (Full Text)] *2015, Using [[gene expression]] signatures to identify novel treatment strategies in gulf war illness<ref>{{Cite journal | last = Craddock | first = Travis J.A. | last2 = Harvey | first2 = Jeanna M. | last3 = Nathanson | first3 = Lubov | last4 = Barnes | first4 = Zachary M. | last5 = Klimas | first5 = Nancy G. | last6 = Fletcher | first6 = Mary Ann | last7 = Broderick | first7 = Gordon | date = 2015-07-09 | title = Using gene expression signatures to identify novel treatment strategies in gulf war illness| url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495687/|journal=BMC Medical Genomics|volume=8|doi=10.1186/s12920-015-0111-3|issn=1755-8794|pmc=4495687|pmid=26156520|issue= | pages = |quote= | author-link = Travis Craddock | authorlink2 = Jeanna Harvey | authorlink3 = Lubov Nathanson | authorlink4 = Zachary Barnes | authorlink5 = Nancy Klimas|via= | authorlink6 = Mary Ann Fletcher | authorlink7 = Gordon Broderick}}</ref> - [https://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-015-0111-3 (Full text)] *2016, Tracking post-infectious fatigue in clinic using routine Lab tests<ref name="Harvey2016">{{Cite journal | last = Harvey | first = Jeanna M. | authorlink = Jeanna Harvey | last2 = Broderick | first2 = Gordon | authorlink2 = Gordon Broderick | last3 = Bowie | first3 = Alanna | authorlink3 = Alanna Bowie | last4 = Barnes | first4 = Zachary M. | authorlink4 = Zachary Barnes | last5 = Katz | first5 = Ben Z. | authorlink5 = Ben Katz | last6 = O'Gorman | first6 = Maurice R.G. | author-link6 = Maurice O'Gorman | last7 = Vernon | first7 = SuzanneD. | authorlink7 = Suzanne Vernon | last8 = Fletcher | first8 = Mary Ann | author-link8 = Mary Ann Fletcher | last9 = Klimas | first9 = Nancy G. | author-link9 = Nancy Klimas | date = 2016-04-26 | title = Tracking post-infectious fatigue in clinic using routine Lab tests| url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847210/|journal=BMC Pediatrics|doi=10.1186/s12887-016-0596-8|issn=1471-2431|pmc=4847210|pmid=27118537|volume=15|issue= | pages = 54|quote=}}</ref> [https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-016-0596-8 (Full Text)] *2016, Illness progression in chronic fatigue syndrome: a shifting immune baseline<ref name="Russell, 2016" /> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785654/ (Full Text)] *2017, Neural Consequences of [[Post-exertional malaise|Post-Exertion Malaise]] in [[ME/CFS|Myalgic Encephalomyelitis/Chronic Fatigue Syndrome]]<ref name="Cook, 2017" /> [http://www.sciencedirect.com/science/article/pii/S088915911730051X (Full Text)] *2018, High-fidelity discrete modeling of the [[HPA axis]]: a study of regulatory plasticity in biology<ref>{{Cite journal | last = Sedghamiz | first = Hooman | last2 = Morris | first2 = Matthew | authorlink2 = Matthew Morris | last3 = Craddock | first3 = Travis J.A. | authorlink3 =Travis Craddock | last4 = Whitley | first4 = Darrell | last5 = Broderick | first5 = Gordon | authorlink5 = Gordon Broderick | date = July 17, 2018 | title = High-fidelity discrete modeling of the HPA axis: a study of regulatory plasticity in biology| url = https://bmcsystbiol.biomedcentral.com/articles/10.1186/s12918-018-0599-1|journal=BMC Systems Biology|volume=12|issue=76 | pages = |doi=10.1186/s12918-018-0599-1|via=}}</ref> [https://bmcsystbiol.biomedcentral.com/articles/10.1186/s12918-018-0599-1 (Abstract)] *2019, Leveraging Prior Knowledge of Endocrine Immune Regulation in the Therapeutically Relevant Phenotyping of Women With Chronic Fatigue Syndrome<ref>{{Cite journal | last = Morris | first = Matthew C. | authorlink = Matthew Morris | last10 = Fletcher | first10 = Mary Ann | authorlink10 = Mary Ann Fletcher | last2 = Cooney | first2 = Katherine E. | authorlink2 = | last3 = Sedghamiz | first3 = Hooman | authorlink3 = | last4 = Abreu | first4 = Maria | authorlink4 = | last5 = Collado | first5 = Fanny | authorlink5 = | last6 = Balbin | first6 = Elizabeth G. | authorlink6 = Elizabeth Balbin | last7 = Craddock | first7 = Travis J.A. | authorlink7 = Travis Craddock | last8 = Klimas | first8 = Nancy G. | author-link8 = Nancy Klimas | last9 = Broderick | first9 = Gordon | author-link9 = Gordon Broderick | date = Mar 2019 | title = Leveraging Prior Knowledge of Endocrine Immune Regulation in the Therapeutically Relevant Phenotyping of Women With Chronic Fatigue Syndrome| url = https://linkinghub.elsevier.com/retrieve/pii/S0149291819301122|journal=Clinical Therapeutics|language=en|volume=|issue= | pages = |doi=10.1016/j.clinthera.2019.03.002|quote=|via=}}</ref> [https://www.sciencedirect.com/science/article/abs/pii/S0149291819301122?via%3Dihub (Abstract)] *2019, From [[Diagnostic biomarker|biomarkers]] to targeted treatment: The myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and gulf war illness (GWI) story<ref>{{Cite journal | last = Klimas | first = N.G. | authorlink = Nancy Klimas | last2 = Fletcher | first2 = M.A. | authorlink2 = Mary Ann Fletcher | last3 = Abreu | first3 = M.M. | authorlink3 = | last4 = Aenlle | first4 = K. | authorlink4 = | last5 = Craddock | first5 = T. | authorlink5 = Travis Craddock | last6 = Broderick | first6 = G. | authorlink6 = Gordon Broderick | date = Feb 2019 | title = From biomarkers to targeted treatment: The myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and gulf war illness (GWI) story| url = https://linkinghub.elsevier.com/retrieve/pii/S0889159118311413|journal=Brain, Behavior, and Immunity|language=en|volume=76|issue=| pages = e40|doi=10.1016/j.bbi.2018.11.301|quote=|via=}}</ref> [https://www.sciencedirect.com/science/article/pii/S0889159118311413?via%3Dihub (Abstract)] *2019, Pharmaceutical Interventions in Chronic Fatigue Syndrome: A Literature-based Commentary<ref>{{Cite journal | last = Richman | first = Spencer | authorlink = | last2 = Morris | first2 = Matthew C. | authorlink2 = Matthew Morris | last3 = Broderick | first3 = Gordon | authorlink3 = Gordon Broderick | last4 = Craddock | first4 = Travis J.A. | authorlink4 = Travis Craddock | last5 = Klimas | first5 = Nancy G. | authorlink5 = Nancy Klimas | last6 = Fletcher | first6 = Mary Ann | date = Mar 2019 | title = Pharmaceutical Interventions in Chronic Fatigue Syndrome: A Literature-based Commentary| url = https://linkinghub.elsevier.com/retrieve/pii/S0149291819300712|journal=Clinical Therapeutics|language=en|volume=|issue= | pages = |doi=10.1016/j.clinthera.2019.02.011|quote=|via= | authorlink6 = Mary Ann Fletcher}}</ref> [[pubmed:30871727|(Abstract)]] *2019, Treatment Avenues in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Split-gender Pharmacogenomic Study of [[Gene expression|Gene-expression]] Modules<ref>{{Cite journal | last = Jeffrey | first = Mary G. | authorlink = | last2 = Nathanson | first2 = Lubov | authorlink2 = Lubov Nathanson | last3 = Aenlle | first3 = Kristina | authorlink3 = | last4 = Barnes | first4 = Zachary M. | authorlink4 = Zachary Barnes | last5 = Baig | first5 = Mirza | authorlink5 = | last6 = Broderick | first6 = Gordon | authorlink6 = Gordon Broderick | last7 = Klimas | first7 = Nancy G. | authorlink7 = Nancy Klimas | last8 = Fletcher | first8 = Mary Ann | author-link8 = Mary Ann Fletcher | last9 = Craddock | first9 = Travis J.A. | author-link9 = Travis Craddock | date = Mar 2019 | title = Treatment Avenues in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Split-gender Pharmacogenomic Study of Gene-expression Modules| url = https://linkinghub.elsevier.com/retrieve/pii/S0149291819300475|journal=Clinical Therapeutics|language=en|volume=|issue= | pages = |doi=10.1016/j.clinthera.2019.01.011|quote=|via=}}</ref> - [[pubmed:30851951|(Abstract)]]
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