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Fibromyalgia
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===<span id="bloodtest">Blood test </span>=== EpicGenetics developed a blood test to identifying the presence of specific [[Leucocyte|white blood cell]] abnormalities of patients diagnosed with FM - '''FM/a® test''' - and announces a linked treatment trial although the trial never started and is now suspended.<ref name="FMa test" /> EpicGenetics offers help to determine if your insurance will cover their test.<ref name="fmtest" /> The FM/a test continues to be marketed despite the suspension of the linked treatment trial,<ref name="FMa test">{{Cite web | last = Faustman | first = Denise Louise | authorlink = | date = 2021-05-27|others=Massachusetts General Hospital | title = Phase II Clinical Trial: Multi-dosing the BCG Vaccine for Fibromyalgia| url = https://clinicaltrials.gov/ct2/show/NCT03582085|pmc=|pmid=|access-date=2021-11-27|quote=|via=}}</ref> and the fact that only two studies have been published using the test - one comparing fibromyalgia patients with healthy controls, and another with lupus and rheumatoid arthritis patients.<ref name="PMC3534336">{{Cite journal | last = Behm | first = Frederick G | last2 = Gavin | first2 = Igor M | last3 = Karpenko | first3 = Oleksiy | last4 = Lindgren | first4 = Valerie | last5 = Gaitonde | first5 = Sujata | last6 = Gashkoff | first6 = Peter A | last7 = Gillis | first7 = Bruce S | date = 2012-12-17 | title = Unique immunologic patterns in fibromyalgia| url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534336/|journal=BMC Clinical Pathology|volume=12 | pages = 25|doi=10.1186/1472-6890-12-25|issn=1472-6890|pmc=3534336|pmid=23245186}}</ref><ref name="PMC4435905">{{Cite journal | last = Wallace | first = Daniel J. | last2 = Gavin | first2 = Igor M. | last3 = Karpenko | first3 = Oleksly | last4 = Barkhordar | first4 = Farnaz | last5 = Gillis | first5 = Bruce S. | date = 2015 | title=Cytokine and chemokine profiles in fibromyalgia, rheumatoid arthritis and systemic lupus erythematosus: a potentially useful tool in differential diagnosis |url =https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435905/|journal=Rheumatology International|volume=35|issue=6 | pages = 991–996|doi=10.1007/s00296-014-3172-2|issn=0172-8172|pmc=4435905|pmid=25377646}}</ref> In the 6 years since the last study was published, no further research has appeared on the FM/a test, leaving many to conclude that the evidence base is weak.<ref name="controversy2021">{{Cite web | last = Boodman | first = Eric | date = Oct 20, 2021 | url =https://www.statnews.com/2021/10/20/selling-certainty-epicgenetics-physician-was-one-of-fibromyalgia-patients-few-true-allies-or-was-he/| title = In a sea of skeptics, this physician was one of fibromyalgia patients’ few true allies. Or was he?| publisher = STAT News}}</ref> IsolateFibromyalgia, IQuity's RNA based blood test for fibromyalgia, was first announced in 2018 but has insufficient data supporting its use: no peer-reviewed studies had been published by 2021.
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