Fexofenadine

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Fexofenadine or fexofenadine hydrochloride is a second generation antihistamine that selectively blocks H1 receptors.[1][2][3][4]

Fexofenadine is primarily used for hayfever, itching including urticaria, and allergies. Fexofenadine is sold under different brand names including Allegra, Aller-Ease, Mucinex Allergy, Wal-Fex, and Allergy Relief (Fexofenadine HCl).[1][2]

Theory[edit | edit source]

Evidence[edit | edit source]

Long COVID[edit | edit source]

Fexofenadine has limited evidence for use in Long COVID patients from a small observational study by Glynne et al. (2022).[5]

Clinicians[edit | edit source]

Risks and safety[edit | edit source]

cannot be taken with apple, orange or grapefruit juices, or other fruit juices.[1]

Costs and availability[edit | edit source]

Fexofenadine is available over the counter or on perscription.[1][2]

Notable studies[edit | edit source]

  • 2022, Long COVID following mild SARS-CoV-2 infection: characteristic T cell alterations and response to antihistamines[5] - (Full text)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 1.2 1.3 "Fexofenadine Uses, Dosage & Side Effects". Drugs.com. Retrieved February 19, 2022.
  2. 2.0 2.1 2.2 "Fexofenadine - Uses, Side Effects, and More". WebMD. Retrieved February 19, 2022.
  3. "Fexofenadine: 7 Things You Should Know". Drugs.com. Retrieved May 22, 2023.
  4. Hogan, Lilianna. "What's the Difference Between First-Generation and Second-Generation Antihistamines?". WebMD. Retrieved May 22, 2023.
  5. 5.0 5.1 Glynne, Paul; Tahmasebi, Natasha; Gant, Vanya; Gupta, Rajeev (January 2022). "Long COVID following mild SARS-CoV-2 infection: characteristic T cell alterations and response to antihistamines". Journal of Investigative Medicine. 70 (1): 61–67. doi:10.1136/jim-2021-002051. ISSN 1081-5589. PMC 8494538. PMID 34611034.