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Fexofenadine
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'''Fexofenadine''' or '''fexofenadine hydrochloride''' is a second generation antihistamine that selectively blocks H1 receptors.<ref name="drugscom">{{Cite web | url = https://www.drugs.com/mtm/fexofenadine.html | title = Fexofenadine Uses, Dosage & Side Effects|website=Drugs.com|language=en|access-date=2022-02-19}}</ref><ref name="webmd">{{Cite web | url = https://www.webmd.com/drugs/2/drug-13823-2204/fexofenadine-oral/fexofenadine-oral/details | title = Fexofenadine - Uses, Side Effects, and More|website=WebMD|language=en|access-date=2022-02-19}}</ref><ref name="tip>{{Cite web | url = https://www.drugs.com/tips/fexofenadine-patient-tips | title = Fexofenadine: 7 Things You Should Know | website=Drugs.com|language=en|access-date=2023-05-22}}</ref><ref name="Second-gen">{{Cite web | url = https://www.webmd.com/allergies/difference-between-first-generation-antihistamines-second-generation-antihistamines | title = What's the Difference Between First-Generation and Second-Generation Antihistamines? | first = Lilianna | last = Hogan | website = WebMD | language=en|access-date=2023-05-22}}</ref> Fexofenadine is primarily used for [[hayfever]], [[skin itch|itching]] including [[urticaria]], and [[allergy|allergies]]. Fexofenadine is sold under different brand names including Allegra, Aller-Ease, Mucinex Allergy, Wal-Fex, and Allergy Relief (Fexofenadine HCl).<ref name="drugscom" /><ref name="webmd"/> ==Theory== ==Evidence== ===Long COVID === Fexofenadine has limited evidence for use in [[Long COVID]] patients from a small observational study by Glynne et al. (2022).<ref name="Glynne2022"/> ==Clinicians== ==Risks and safety== cannot be taken with apple, orange or grapefruit juices, or other fruit juices.<ref name="drugscom" /> ==Costs and availability== Fexofenadine is available over the counter or on perscription.<ref name="drugscom" /><ref name="webmd" /> ==Notable studies == *2022, Long COVID following mild SARS-CoV-2 infection: characteristic T cell alterations and response to antihistamines<ref name="Glynne2022">{{Cite journal | title = Long COVID following mild SARS-CoV-2 infection: characteristic T cell alterations and response to antihistamines | date = Jan 2022| url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494538/|journal=Journal of Investigative Medicine|volume=70|issue=1 | pages = 61β67 | last = Glynne | first = Paul | authorlink = Paul Glynne | last2 = Tahmasebi | first2 = Natasha | authorlink2 = | last3 = Gant | first3 = Vanya | authorlink3 = | last4 = Gupta | first4 = Rajeev | authorlink4 = |doi=10.1136/jim-2021-002051|pmc=8494538|pmid=34611034|access-date=|issn=1081-5589|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494538/ (Full text)] ==See also == *[[Allergy]] *[[Histamine]] *[[Urticaria]] *[[Long COVID]] ==Learn more == *[https://www.drugs.com/mtm/fexofenadine.html fexofenadine] - drugs.com *[https://www.webmd.com/drugs/2/drug-13823-2204/fexofenadine-oral/fexofenadine-oral/details fexofenadine] - WebMD * [https://www.drugs.com/tips/fexofenadine-patient-tips Fexofenadine: 7 Things You Should Know] - Drugs.com ==References== {{reflist}} [[Category:Potential treatments]] [[Category:Antihistamines]] [[Category:H1 antihistamines]] [[Category:Non-sedating antihistamines]]
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