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[[File:Chronic-Fatigue-Patil.jpg|3206px|right|thumb|Source: Chronic fatigue syndrome: A review (Balachander et al.) 2014.<ref name=":03">{{Cite journal | last = Singh | first = Shubh Mohan | last2 = Sarkar | first2 = Siddharth | last3 = Rao | first3 = Pradyumna | last4 = Balachander | first4 = Srinivas | date = 2014-07-01 | title = Chronic fatigue syndrome: A review | url = http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2014;volume=7;issue=4;spage=415;epage=422;aulast=Balachander|journal=Medical Journal of Dr.D.Y. Patil University|language=en|volume=7|issue=4 | pages = 415|doi=10.4103/0975-2870.135252|issn=0975-2870|quote=|via=}}</ref>]] '''Fatigue''' is a feeling of subjective feeling of tiredness, often called by other names including exhaustion. Persistent physical fatigue is a core symptom of [[chronic fatigue syndrome]] and a common symptom in many other chronic health conditions.<ref name=":0">{{Cite journal | last = Jason | first = Leonard A. | author-link = Leonard Jason | last2 = Boulton | first2 = Aaron | authorlink2 = Aaron Boulton | last3 = Porter | first3 = Nicole S. | authorlink3 = Nicole Porter | last4 = Jessen | first4 = Tricia | authorlink4 = Tricia Jessen | last5 = Njoku | first5 = Mary Gloria | authorlink5 = Mary Gloria Njoku | date = 2010 | title=Classification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome by Types of Fatigue | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852700/|journal=Behavioral medicine (Washington,D.C.)|volume=36|issue=1 | pages = 24β31|doi=10.1080/08964280903521370|issn=0896-4289|pmc=4852700|pmid=20185398|via=}}</ref><ref name=":1" /> === Types of fatigue === {{Image frame|caption=1.Post-exertional 2.Wired but tired 3.Brain fog<br>4.Lack of energy for daily life 5. Flu-like fatigue<br>Source: Jason et al 2009, Disability Studies Quarterly 29(3).<ref name=":2"/>|content={{Graph:Chart|width=300|height=auto|type=rect|xAxisTitle=Type of fatigue in patients with M.E./CFS|yAxisTitle=MFTQ Score|legend=Legend|x=1,2,3,4,5|y1=169,132,160,139,141|y2=11,33,26,21,35|showValues=|y2Title=Healthy controls|colors={{MEActionRed}},{{MEActionBlue}}|y1Title=ME/CFS}} |link=[[File:Types of fatigue in ME_CFS.png]]}} A number of different types of fatigue have been described in people with [[ME/CFS]]: # [[Post-exertional malaise|Post-exertional fatigue]] # [[Wired fatigue]] (wired but tired) # [[Cognitive dysfunction|Brain fog]] # [[Substantial reduction or impairment in the ability to engage in pre-illness levels of occupational, educational, social, or personal activities|Lack of energy for daily living activities]] # [[Flu-like symptoms|Flu-like fatigue]]<ref name=":2">{{Cite journal | last = Jason | first = Leonard | authorlink = Leonard Jason | last2 = Jessen | first2 = Tricia | authorlink2 = Tricia Jessen | last3 = Porter | first3 = Nicole | authorlink3 = Nicole Porter | last4 = Boulton | first4 = Aaron | authorlink4 = Aaron Boulton | last5 = Njoku | first5 = Mary Gloria | authorlink5 = Mary Gloria Njoku | date = 2009-07-16 | title = Examining Types of Fatigue Among Individuals with ME/CFS| url = http://dsq-sds.org/article/view/938|journal=Disability Studies Quarterly|language=en|volume=29|issue=3| pages=|issn=2159-8371|via=}}</ref> <br style="clear:both"> ==Prevalence== ==Symptom recognition== Persistent fatigue which is [[not relieved by rest]], not life-long, persists over the long term, and does not result from another health condition is a compulsory symptom of [[chronic fatigue syndrome]] in the [[Fukuda criteria]].<ref name="fukuda1994">{{Cite journal | last = Fukuda | first = K. | author-link = Keiji Fukuda | last2 = Straus | first2 = S.E. | authorlink2 = Stephen Straus | last3 = Hickie | first3 = I. | authorlink3 = Ian Hickie | last4 = Sharpe | first4 = M. C. | authorlink4 = Michael Sharpe | last5 = Dobbins | first5 = J. G. | authorlink5 = James Dobbins | last6 = Komaroff | first6 = A. | authorlink6 = Anthony Komaroff | date = 1994-12-15 | title = The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group | url = https://www.researchgate.net/profile/Michael_Sharpe2/publication/247808895_The_Chronic_Fatigue_Syndrome_A_Comprehensive_Approach_to_Its_Definition_and_Study/links/0c96053201643bfc4b000000/The-Chronic-Fatigue-Syndrome-A-Comprehensive-Approach-to-Its-Definition-and-Study.pdf | journal=Annals of Internal Medicine|volume=121|issue=12 | pages = 953β959|issn=0003-4819|pmid=7978722| publisher = American College of Physicians|ref=fukuda1994}}</ref> Multiple types of fatigue are common but optional symptoms of the [[International Consensus Criteria]] and [[Canadian Consensus Criteria]] for [[Myalgic Encephalomyelitis]].<ref name=":1">{{Cite journal | last = Carruthers | first = B.M. | last2 = van de Sande | first2 = M.I. | last3 = De Meirleir | first3 = K.L. | last4 = Klimas | first4 = N.G. | last5 = Broderick | first5 = G. | last6 = Mitchell | first6 = T. | last7 = Staines | first7 =D. | last8 = Powles | first8 = A.C.P. | last9 = Speight | first9 = N. | date = 2011-10-01 | title = Myalgic encephalomyelitis: International Consensus Criteria| url = http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2796.2011.02428.x/full|journal=Journal of Internal Medicine|language=en|volume=270|issue=4|doi=10.1111/j.1365-2796.2011.02428.x/full|issn=1365-2796| pages=|via=}}</ref> Fatigue is one of the most common [[Long COVID]] symptoms.<ref name="WHO-longcovid-criteria">{{citation | title = A clinical case definition of post COVID-19 condition by a Delphi consensus | date =Oct 6, 2021 | publisher = [[World Health Organization]] | others = World Health Organization (WHO) clinical case definition working group on post COVID-19 condition | first1 = Joan B. | last1 = Soriano | first2 = Maya | last2 = Allan | first3 = Carine | last3 = Alsokhn | first4 = Nisreen A. | last4 = Alwan | authorlink4 = Nisreen Alwan | first5 = Lisa | last5 = Askie | first6 = Hannah E. | last6 = Davis | authorlink6 = Hannah Davis | first7 = Janet V. | last7 = Diaz | first8 = Tarun | last8 = Dua | first9 = Wouter | last9 = de Groote | first10 = Robert | last10 = Jakob | first11 = Marta | last11 = Lado | first12 = John | last12 = Marshall | first13 = Srin | last13 = Murthy | first14 = Jacobus | last14 = Preller | first15 = Pryanka | last15 = Relan | first16 = Nicoline | last16 = Schiess | first17 = Archana | last17 = Seahwag | ref = WHO reference number: WHO/2019-nCoV/Post_COVID-19_condition/Clinical_case_definition/2021.1 | url = https://www.who.int/publications-detail-redirect/WHO-2019-nCoV-Post_COVID-19_condition-Clinical_case_definition-2021.1}}</ref> ==Notable studies== *2009, Examining Types of Fatigue Among Individuals with ME/CFS<ref name=":2" /> ([http://dsq-sds.org/article/view/938 Full Text]) *2010, Classification of [[ME/CFS|Myalgic Encephalomyelitis/Chronic Fatigue Syndrome]] by Types of Fatigue<ref name=":0" /> ([https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852700/ Full Text]) *2014, Chronic fatigue syndrome: A review<ref name=":03" /> ([http://www.mjdrdypu.org/article.asp?issn=0975-2870;year=2014;volume=7;issue=4;spage=415;epage=422;aulast=Balachander Full Text]) *2016, The aetiopathogenesis of fatigue: unpredictable, complex and persistent<ref>{{Cite journal | last = Clark | first = James E. | last2 = Fai Ng | first2 = W. | last3 = Watson | first3 = Stuart | last4 = Newton | first4 = Julia L. | date = Mar 2016 | title = The aetiopathogenesis of fatigue: unpredictable, complex and persistent| url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782751/|journal=British Medical Bulletin|volume=117|issue=1 | pages = 139β148|doi=10.1093/bmb/ldv057|issn=0007-1420|pmc=4782751|pmid=26872857}}</ref> ([https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782751/ Full Text]) *2018, Association of [[Sleep dysfunction|sleep disorders]], [[chronic pain]], and fatigue with survival in patients with chronic kidney disease: A meta-analysis of clinical trials<ref>{{Cite journal | last = Yang | first = Xiu Hong | last2 = Zhang | first2 = Bao Long | last3 = Gu | first3 = Yan Hong | last4 = Zhan | first4 = Xiao Li | last5 = Guo | first5 = Li Li | last6 = Jin | first6 = Hui Min | date = 2018-11-01 | title = Association of sleep disorders, chronic pain, and fatigue with survival in patients with chronic kidney disease: a meta-analysis of clinical trials |url = http://www.sciencedirect.com/science/article/pii/S1389945718303976|journal=Sleep Medicine|volume=51 | pages = 59β65|doi=10.1016/j.sleep.2018.06.020|issn=1389-9457}}</ref> ([https://www.sleep-journal.com/article/S1389-9457(18)30397-6/abstract Full Text]) ==Potential treatments== ==See also== * [[Chronic fatigue]] * [[Idiopathic chronic fatigue]] * [[Chronic fatigue syndrome]] * [[Myalgic encephalomyelitis]] * [[Post-exertional malaise]] * [[Common symptoms in ME/CFS]] ==Learn more== * [https://www.docsopinion.com/2017/11/08/causes-fatigue-tiredness-chronic-fatigue/ 19 Important Causes of Fatigue β Tiredness and Chronic Fatigue Explained]<ref name=":02">{{Cite web | url = https://www.docsopinion.com/2017/11/08/causes-fatigue-tiredness-chronic-fatigue/ | title = 19 Important Causes of Fatigue - Tiredness and Chronic Fatigue Explained | last = Sigurdsson MD| first = Alex F. | authorlink = | date = Nov 8, 2017 | website = docsopinion.com|archive-url=|archive-date=|url-status=|access-date=2019-01-30}}</ref> * 2010, Classification of [[ME/CFS|Myalgic Encephalomyelitis/Chronic Fatigue Syndrome]] by Types of Fatigue<ref name=":0" /> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852700/ (Full Text)] ==References== {{Reflist}} [[Category:Long COVID signs and symptoms]] [[Category:Signs and symptoms]] [[Category:Energy system]]
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