FINE trial

The FINE trial was a study examining treatments for ME/CFS. It is considered to be the 'sister' to the PACE trial.

Results

Sam Carter applied the criteria from a PACE trial study to the data from the FINE trial and questioned whether the recovery rates in the PACE study had been inflated by as much as six-fold as a result.

Criticism

• 2015, Trial By Error, Continued: Why has the PACE Study’s “Sister Trial” been “Disappeared” and Forgotten?
• 2010, Not So Fine After All: the FINE Trial Crashes to Earth
• FINE Trials Experience
• Failure of FINE trial comes as no surprise’ – MEA responds to study results in British Medical Journal
• Add to FINE page https://forbetterscience.wordpress.com/2016/05/20/plos-correction-removes-previously-available-anonymised-patient-clinical-trial-data/

Consent Form

• Add FINE consent form http://retractionwatch.com/wp-content/uploads/2016/05/11.4.16-Mitchell-Response-consent-form-version3-MREC-2460904.pdf

Investigators

Alison Wearden, Riste L, Dowrick C, Chew-Graham C, Bentall RP, Richard Morriss, Peters S, Dunn G, Richardson G, Lovell K, Powell P.

Learn more

• FINE trial website

See also

• PACE trial

PACE trial A controversial study which claimed that CBT and GET were effective in treating "CFS/ME", despite the fact that its own data did not support this conclusion. Its results and methodology were widely disputed by patients, scientists, and the peer-reviewed scientific literature.