Evening primrose oil
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Evening primrose oil supplement. Image: Open Food Facts
Evening primrose oil is a medicinal oil derived from the evening primrose (Oenothera) plant. It is rich in gamma linolenic acid (GLA), an omega 6 essential fatty acid.[1]
Potential uses[edit | edit source]
- Treatment of food sensitivities in leaky gut
- Candida
Theory[edit | edit source]
Evidence[edit | edit source]
ME/CFS[edit | edit source]
Notable studies[edit | edit source]
- 1996, Cognitive behaviour therapy for the chronic fatigue syndrome. Evening primrose oil and magnesium have been shown to be effective[2] (Full text)
- 2004, The use of eicosapentaenoic acid in the treatment of chronic fatigue syndrome[3] (Abstract)
- 2005, In chronic fatigue syndrome, the decreased levels of omega-3 poly-unsaturated fatty acids are related to lowered serum zinc and defects in T cell activation[4] (Full text)
- 2007, Long-chain polyunsaturated fatty acids and the pathophysiology of myalgic encephalomyelitis (chronic fatigue syndrome)[5] (Abstract)
Efamol marine[edit | edit source]
- 1990, A placebo-controlled trial of n-3, n-6, essential fatty acids in the treatment of postviral fatigue syndrome[6] (Abstract)
- 1999, The role of essential fatty acids in chronic fatigue syndrome: A case‐controlled study of red‐cell membrane essential fatty acids (EFA) and a placebo‐controlled treatment study with high dose of EFA[7] (Full text)
- Found no overall benefit was found for efamol marine.
Risks and safety[edit | edit source]
Costs and availability[edit | edit source]
Fatty acid blends containing evening primose oil invoice efamol marine, which adds fish oil and overall contains 57% v-linoleic acid, 7.2% GLA, and 3.6% EPAs and 2.4% DHA.[7][4]
See also[edit | edit source]
- Eicosapentaenoic acid (EPA)
- Docosahexaenoic acid (DHA]]
- Fatty acid hypothesis
- Fish oil
- Fatty acids (category)
References[edit | edit source]
- ↑ University of Maryland Medical Center - Gamma-linolenic acid
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2350915/
- ↑ https://www.sciencedirect.com/science/article/pii/S0952327804000122
- ↑ 4.0 4.1 https://pubmed.ncbi.nlm.nih.gov/16380690/
- ↑ https://pubmed.ncbi.nlm.nih.gov/16935966/
- ↑ https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0404.1990.tb04490.x
- ↑ 7.0 7.1 https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0404.1999.tb00667.x
