Epstein-Barr virus induced gene 2

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Epstein-Barr virus induced gene 2 or EBI2.


Function[edit | edit source]

ME/CFS[edit | edit source]

Notable studies[edit | edit source]

  • 2008, Gene expression subtypes in patients with chronic fatigue syndrome/myalgic encephalomyelitis[1] (Full text)
  • 2019, Epstein-barr virus induced gene-2 upregulation identifies a particular subtype of chronic fatigue syndrome/myalgic encephalomyelitis[2] (Full text)
  • 2020, Early Growth Response Gene Upregulation in Epstein–Barr Virus (EBV)-Associated Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)[3] (Full text)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. ↑ Kerr, Jonathan R.; Petty, Robert; Burke, Beverley; Gough, John; Fear, David; Sinclair, Lindsey I.; Mattey, Derek L.; Richards, Selwyn C. M.; Montgomery, Jane; Baldwin, Don A.; Kellam, Paul (2008). "Gene Expression Subtypes in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis". The Journal of Infectious Diseases. 197 (8): 1171–1184. ISSN 0022-1899.
  2. ↑ Kerr, Jonathan R. (2019). "Epstein-Barr Virus Induced Gene-2 Upregulation Identifies a Particular Subtype of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis". Frontiers in Pediatrics. 7: 59. doi:10.3389/fped.2019.00059. ISSN 2296-2360.
  3. ↑ Kerr, Jonathan (October 26, 2020). "Early Growth Response Gene Upregulation in Epstein–Barr Virus (EBV)-Associated Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)". Biomolecules. 10 (11): 1484. doi:10.3390/biom10111484. ISSN 2218-273X. PMC 7692278. PMID 33114612.

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.

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