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Epigallocatechin gallate
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=== SARS-CoV-2 & CD147 === The SARS-CoV-2 virus can invade host cells not only via the ACE2 receptor, but also via the CD147/EMMPRIN receptor,<ref>{{Cite journal | last = Wang | first = Ke | last2 = Chen | first2 = Wei | last3 = Zhou | first3 = Yu-Sen | last4 = Lian | first4 = Jian-Qi | last5 = Zhang | first5 = Zheng | last6 = Du | first6 = Peng | last7 = Gong | first7 = Li | last8 = Zhang | first8 = Yang | last9 = Cui | first9 = Hong-Yong | date = 2020-03-14 | title = SARS-CoV-2 invades host cells via a novel route: CD147-spike protein | url =https://www.biorxiv.org/content/10.1101/2020.03.14.988345v1|journal=bioRxiv|language=en | pages = 2020.03.14.988345|doi=10.1101/2020.03.14.988345}}</ref> meaning EGCG may have beneficial effects in the context COVID-19. EGCG have also been shown to have antifibrotic effects in a human study testing 600 mg oral EGCG/day in patients with pulmonary fibrosis undergoing lung biopsy.<ref>{{Cite journal | last = Chapman | first = Harold A. | last2 = Wei | first2 = Ying | last3 = Montas | first3 = Genevieve | last4 = Leong | first4 = Darren | last5 = Golden | first5 = Jeffrey A. | last6 = Trinh | first6 = Binh N. | last7 = Wolters | first7 = Paul J. | last8 = Le Saux | first8 = Claude J. | last9 = Jones | first9 = KirkD. | date = 2020-03-12 | title = Reversal of TGFΞ²1-Driven Profibrotic State in Patients with Pulmonary Fibrosis |url =https://doi.org/10.1056/NEJMc1915189|journal=New England Journal of Medicine|volume=382|issue=11 | pages = 1068β1070|doi=10.1056/NEJMc1915189|issn=0028-4793|pmid=32160670}}</ref> This mean that EGCG, apart from potentially having an antiviral effect against the SARS-CoV-2 virus, might reduce the risk of lung scarring from COVID-19.
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