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Enterovirus
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==== Polymerase chain reaction ==== In a study of serum samples from 100 CFS patients and 100 healthy controls, 42% of patients were positive for Coxsackie B sequences by polymerase chain reaction (PCR), compared to only 9% of the comparison group.<ref>{{Cite journal | last = Nairn | first = C | date = August 1995 | title = Comparison of coxsackie B neutralisation and enteroviral PCR in chronic fatigue patients |url =https://www.ncbi.nlm.nih.gov/pubmed/7595406|journal=Journal of Medical Virology|volume= | pages = |via=}}</ref> Also using PCR, a study of 236 patients by John Chia found enteroviral [[RNA]] in 48% of patients as compared to 8% of controls.To date, Chia reports finding enteroviral RNA in 35% of 518 patients.<ref name=":04">{{Cite journal | last = Chia | first = John | date = November 2005 | title = The role of enterovirus in chronic fatigue syndrome | url =https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770761/|journal=Journal of Clinical Pathology|volume= | pages = |via=}}</ref>
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