Elizabeth Unger: Difference between revisions

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[[File:Beth-Unger.jpg|200px|right]]
[[File:Beth-Unger.jpg|200px|right]]
'''Elizabeth (Beth) R. Unger''', MD, PhD, is the Chief of the Chronic Viral Disease Branch (CVDB), Division of High-Consequence Pathogens and Pathology, [[National Center for Emerging and Zoonotic Infectious Diseases]] at the [[Centers for Disease Control and Prevention]] (CDC), Atlanta, Georgia. [[chronic fatigue syndrome]] (CFS) research falls under her department. She has worked at the CDC since 1997 and replaced Dr. [[William Reeves]] as Chief of CVDB in 2010.<ref name=":1">{{Cite web|url=https://www.cdc.gov/me-cfs/index.html|title=Myalgic Encephalomyelitis/Chronic Fatigue Syndrome|date=2019-08-08|website=[[Centers for Disease Control and Prevention]]|language=en-us|access-date=2019-09-03}}</ref> Dr. Unger has done extensive research at the CDC on the [[human papillomavirus]] (HPV).  
'''Elizabeth (Beth) R. Unger''', MD, PhD, is the Chief of the Chronic Viral Disease Branch (CVDB), Division of High-Consequence Pathogens and Pathology, [[National Center for Emerging and Zoonotic Infectious Diseases]] at the [[Centers for Disease Control and Prevention]] (CDC), Atlanta, Georgia. [[chronic fatigue syndrome]] (CFS) research falls under her department. She has worked at the CDC since 1997 and replaced Dr. [[William Reeves]] as Chief of CVDB in 2010.<ref name=":1">{{Cite web | url=https://www.cdc.gov/me-cfs/index.html | title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome | date = 2019-08-08 | website = [[Centers for Disease Control and Prevention]]|language=en-us|access-date=2019-09-03}}</ref> Dr. Unger has done extensive research at the CDC on the [[human papillomavirus]] (HPV).  


In 2002-2003, Dr Unger was on the team that tested the validity of 1994 CDC case definition of [[Chronic fatigue syndrome|CFS]], known as the [[empirical definition]] or [[Fukuda criteria]], via the [[Wichita Clinical Study]]. The study, according to the CDC, "identifies persons with CFS in a precise manner that can be readily reproduced by both investigators and clinicians."<ref>http://www.cdc.gov/cfs/case-definition/1994.html</ref><ref name=":0">{{Cite journal|last=Reeves|first=William C.|author-link=William Reeves|last2=Wagner|first2=Dieter|author-link2=Dieter Wagner|last3=Nisenbaum|first3=Rosane|author-link3=Rosane Nisenbaum|last4=Jones|first4=James F.|author-link4=James Jones|last5=Gurbaxani|first5=Brian|author-link5=Brian Gurbaxani|last6=Solomon|first6=Laura|author-link6=Laura Solomon|last7=Papanicolaou|first7=Dimitris A.|author-link7=Dimitris Papanicolaou|last8=Unger|first8=Elizabeth R.|author-link8=Elizabeth Unger|last9=Vernon|first9=Suzanne D.|author-link9=Suzanne Vernon|last10=Heim|first10= Christine|authorlink10=Christine Heim|date=2005-12-15|title=Chronic Fatigue Syndrome – A clinically empirical approach to its definition and study|url=https://doi.org/10.1186/1741-7015-3-19|journal=BMC Medicine|volume=3|issue=1|pages=19|doi=10.1186/1741-7015-3-19|issn=1741-7015|pmc=1334212|pmid=16356178|quote=|via=}}</ref> Many researchers continued to use the Fukuda criteria for research.
In 2002-2003, Dr Unger was on the team that tested the validity of 1994 CDC case definition of [[Chronic fatigue syndrome|CFS]], known as the [[empirical definition]] or [[Fukuda criteria]], via the [[Wichita Clinical Study]]. The study, according to the CDC, "identifies persons with CFS in a precise manner that can be readily reproduced by both investigators and clinicians."<ref>http://www.cdc.gov/cfs/case-definition/1994.html</ref><ref name=":0">{{Cite journal | last = Reeves | first = William C. | author-link = William Reeves | last2 = Wagner | first2 = Dieter | authorlink2 = Dieter Wagner | last3 = Nisenbaum | first3 = Rosane | authorlink3 = Rosane Nisenbaum | last4 = Jones | first4 = James F. | authorlink4 = James Jones | last5 = Gurbaxani | first5 = Brian | authorlink5 = Brian Gurbaxani | last6 = Solomon | first6 = Laura | author-link6 = Laura Solomon | last7 = Papanicolaou | first7 = Dimitris A. | author-link8 = Dimitris Papanicolaou | last8 = Unger | first8 = Elizabeth R. | author-link8 = Elizabeth Unger | last9 = Vernon | first9 = Suzanne D. | author-link9 = Suzanne Vernon | last10 = Heim | first10 = Christine | author-link10 = Christine Heim | date = 2005-12-15 | title = Chronic Fatigue Syndrome – A clinically empirical approach to its definition and study| url = https://doi.org/10.1186/1741-7015-3-19|journal=BMC Medicine|volume=3|issue=1 | pages = 19|doi=10.1186/1741-7015-3-19|issn=1741-7015|pmc=1334212|pmid=16356178|quote=|via=}}</ref> Many researchers continued to use the Fukuda criteria for research.


==Chronic Fatigue Syndrome Advisory Committee==
==Chronic Fatigue Syndrome Advisory Committee==
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==Notable publications related to ME/CFS==
==Notable publications related to ME/CFS==
*2003, Prevalence and Incidence of Chronic Fatigue Syndrome in Wichita, Kansas - [https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/215827 (Full Text)]
*2003, Prevalence and Incidence of Chronic Fatigue Syndrome in Wichita, Kansas - [https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/215827 (Full Text)]
*2003, Identification of ambiguities in the [[Fukuda criteria|1994 chronic fatigue syndrome research case definition]] and recommendations for resolution<ref name="Reeves,2003">{{Citation|last1=Reeves|first1=W.C.|authorlink1=William Reeves|last2=Lloyd|first2=A.|authorlink2=Andrew Lloyd|last3=Vernon|first3=S.D.|authorlink3=Suzanne Vernon|last4=Klimas|first4=N.|authorlink4=Nancy Klimas|last5=Jason|first5=L.A.|authorlink5=Leonard Jason|last6=Bleijenberg|first6=G.|authorlink6=Gijs Bleijenberg|last7=Evengard|first7=B.|authorlink7=Birgitta Evengård|last8=White|first8=P.D.|authorlink8=Peter White|last9=Nisenbaum|first9=R.|authorlink9=Rosane Nisenbaum|last10=Unger|first10=E.|authorlink10=Elizabeth Unger|title=Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution|journal=BMC Health Services Research|volume=3|issue=25|date=2003|doi=10.1186/1472-6963-3-25}}</ref> - [https://bmchealthservres.biomedcentral.com/articles/10.1186/1472-6963-3-25 (Full Text)]
*2003, Identification of ambiguities in the [[Fukuda criteria|1994 chronic fatigue syndrome research case definition]] and recommendations for resolution<ref name="Reeves,2003">{{Citation | last1 = Reeves | first1 = W.C. | authorlink = William Reeves | last2 = Lloyd | first2 = A. | authorlink2 = Andrew Lloyd | last3 = Vernon | first3 = S.D. | authorlink3 = Suzanne Vernon | last4 = Klimas | first4 = N. | authorlink4 = Nancy Klimas | last5 = Jason | first5 = L.A. | authorlink5 = Leonard Jason | last6 = Bleijenberg | first6 = G. | author-link6 = Gijs Bleijenberg | last7 = Evengard | first7 = B. | author-link8 = Birgitta Evengård | last8 = White | first8 = P.D. | author-link8 = Peter White | last9 = Nisenbaum | first9 = R. | author-link9 = Rosane Nisenbaum | last10 = Unger | first10 = E. | author-link10 = Elizabeth Unger | title = Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution|journal=BMC Health Services Research|volume=3|issue=25 | date = 2003 | doi=10.1186/1472-6963-3-25}}</ref> - [https://bmchealthservres.biomedcentral.com/articles/10.1186/1472-6963-3-25 (Full Text)]
*2004, Factor analysis of symptoms among subjects with unexplained chronic fatigue: what can we learn about chronic fatigue syndrome?<ref name="Nisenbaum, 2004" /> - [https://www.ncbi.nlm.nih.gov/pubmed/15016574 (Abstract)]
*2004, Factor analysis of symptoms among subjects with unexplained chronic fatigue: what can we learn about chronic fatigue syndrome?<ref name="Nisenbaum, 2004" /> - [https://www.ncbi.nlm.nih.gov/pubmed/15016574 (Abstract)]
*2005, [[Chronic Fatigue Syndrome]] – A clinically empirical approach to its definition and study.<ref name=":0" />
*2005, [[Chronic Fatigue Syndrome]] – A clinically empirical approach to its definition and study.<ref name=":0" />
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*2006, Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study<ref name="Reeves,2006" /> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483445/ (Full Text)]
*2006, Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study<ref name="Reeves,2006" /> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483445/ (Full Text)]
*2007, Perception versus polysomnographic assessment of [[Sleep dysfunction|sleep]] in [[Chronic fatigue syndrome|CFS]] and non-fatigued control subjects: results from a population-based study<ref name="Majer, 2007" /> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231384/ (Full Text)]
*2007, Perception versus polysomnographic assessment of [[Sleep dysfunction|sleep]] in [[Chronic fatigue syndrome|CFS]] and non-fatigued control subjects: results from a population-based study<ref name="Majer, 2007" /> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231384/ (Full Text)]
*2009, An evaluation of exclusionary medical/psychiatric conditions in the definition of chronic fatigue syndrome<ref>{{Cite journal|last=Jones|first=James F|author-link=|last2=Lin|first2=Jin-Mann S|author-link2=|last3=Maloney|first3=Elizabeth M|author-link3=|last4=Boneva|first4=Roumiana S|author-link4=|last5=Nater|first5=Urs M|author-link5=|last6=Unger|first6=Elizabeth R|author-link6=|last7=Reeves|first7=William C|date=Dec 2009|title=An evaluation of exclusionary medical/psychiatric conditions in the definition of chronic fatigue syndrome|url=http://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-7-57|journal=BMC Medicine|language=en|volume=7|issue=1|pages=|doi=10.1186/1741-7015-7-57|issn=1741-7015|pmc =  2768736|pmid=19818157|access-date=|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768736/ (Full Text)]
*2009, An evaluation of exclusionary medical/psychiatric conditions in the definition of chronic fatigue syndrome<ref>{{Cite journal | last = Jones | first = James F | authorlink = | last2 = Lin | first2 = Jin-Mann S | authorlink2 = | last3 = Maloney | first3 = Elizabeth M | authorlink3 = | last4 = Boneva | first4 = Roumiana S | authorlink4 = | last5 = Nater | first5 = Urs M | authorlink5 = | last6 = Unger | first6 = Elizabeth R | author-link6 = | last7 = Reeves | first7 = William C | date = Dec 2009 | title = An evaluation of exclusionary medical/psychiatric conditions in the definition of chronic fatigue syndrome | url =http://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-7-57|journal=BMC Medicine|language=en|volume=7|issue=1 | pages = |doi=10.1186/1741-7015-7-57|issn=1741-7015|pmc =  2768736|pmid=19818157|access-date=|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2768736/ (Full Text)]
*2012, Minimum data elements for research reports on CFS<ref name="Jason,Unger 2012" /> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643273/ (Full text)]
*2012, Minimum data elements for research reports on CFS<ref name="Jason,Unger 2012" /> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643273/ (Full text)]
*2013, Acute psychosocial [[stress]]-mediated changes in the expression and methylation of perforin in chronic fatigue syndrome<ref>{{Cite journal|last=Falkenberg|first=Virginia R|author-link=|last2=Whistler|first2=Toni|author-link2=|last3=Murray|first3=Janna R|author-link3=|last4=Unger|first4=Elizabeth R|author-link4=Elizabeth Unger|last5=Rajeevan|first5=Mangalathu S|author-link5=Mangalathu Rajeevan|date=2013|title=Acute Psychosocial Stress-Mediated Changes in the Expression and Methylation of Perforin in Chronic Fatigue Syndrome|url=|journal=Genetics and Epigenetics|volume=5|issue=|pages=1-9|doi=10.4137/GEG.S10944|pmc=4222335|pmid=25512702|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222335/ (Full Text)]
*2013, Acute psychosocial [[stress]]-mediated changes in the expression and methylation of perforin in chronic fatigue syndrome<ref>{{Cite journal | last = Falkenberg | first = Virginia R | author-link = | last2 = Whistler | first2 = Toni | authorlink2 = | last3 = Murray | first3 = Janna R | authorlink3 = | last4 = Unger | first4 = Elizabeth R | authorlink4 = Elizabeth Unger | last5 = Rajeevan | first5 = Mangalathu S | authorlink5 = Mangalathu Rajeevan | date = 2013 | title = Acute Psychosocial Stress-Mediated Changes in the Expression and Methylation of Perforin in Chronic Fatigue Syndrome | url =|journal=Genetics and Epigenetics|volume=5|issue= | pages = 1-9|doi=10.4137/GEG.S10944|pmc=4222335|pmid=25512702|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222335/ (Full Text)]
*2014, Chronic Fatigue Syndrome: The Current Status and Future Potentials of Emerging [[Biomarker]]s<ref name="Fischer, 2014" /> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052724/ (Full Text)]
*2014, Chronic Fatigue Syndrome: The Current Status and Future Potentials of Emerging [[Biomarker]]s<ref name="Fischer, 2014" /> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052724/ (Full Text)]
*2014, Decreased basal ganglia activation in subjects with [[chronic fatigue syndrome]]: association with symptoms of fatigue<ref name="Miller2015">{{Cite journal|last=Miller|first=Andrew H.|author-link=Andrew Miller|last2=Jones|first2=James F.|author-link2=James Jones|last3=Drake|first3=Daniel F.|author-link3=Daniel Drake|last4=Tian|first4=Hao|author-link4=Hao Tian|last5=Unger|first5=Elizabeth R.|author-link5=Elizabeth Unger|last6=Pagnoni|first6=Giuseppe|author-link6=Giuseppe Pagnoni|date=2014-05-23|title=Decreased Basal Ganglia Activation in Subjects with Chronic Fatigue Syndrome: Association with Symptoms of Fatigue|url=https://dx.org/10.1371/journal.pone.0098156|journal=PLoS ONE|volume=9|issue=5|pages=e98156|doi=10.1371/journal.pone.0098156|issn=1932-6203|pmc=4032274|pmid=24858857|access-date=|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032274/ (Full Text)]
*2014, Decreased basal ganglia activation in subjects with [[chronic fatigue syndrome]]: association with symptoms of fatigue<ref name="Miller2015">{{Cite journal | last = Miller | first = Andrew H. | author-link = Andrew Miller | last2 = Jones | first2 = James F. | authorlink2 = James Jones | last3 = Drake | first3 = Daniel F. | authorlink3 = Daniel Drake | last4 = Tian | first4 = Hao | authorlink4 = Hao Tian | last5 = Unger | first5 = Elizabeth R. | authorlink5 = Elizabeth Unger | last6 = Pagnoni | first6 = Giuseppe | author-link6 = Giuseppe Pagnoni | date = 2014-05-23 | title = Decreased Basal Ganglia Activation in Subjects with Chronic Fatigue Syndrome: Association with Symptoms of Fatigue | url =https://dx.org/10.1371/journal.pone.0098156|journal=PLoS ONE|volume=9|issue=5| pages = e98156|doi=10.1371/journal.pone.0098156|issn=1932-6203|pmc=4032274|pmid=24858857|access-date=|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032274/ (Full Text)]
*2015, Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome<ref>{{Cite journal|last=Rajeevan|first=Mangalathu S.|author-link=Mangalathu Rajeevan|last2=Dimulescu|first2=Irina|author-link2=|last3=Murray|first3=Janna|author-link3=|last4=Falkenberg|first4=Virginia R.|author-link4=|last5=Unger|first5=Elizabeth R.|author-link5=Elizabeth Unger|date=2015-08-01|title=Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome|url=https://www.sciencedirect.com/science/article/pii/S0198885915001809|journal=Human Immunology|language=en|volume=76|issue=8|pages=553–560|doi=10.1016/j.humimm.2015.06.014|issn=0198-8859|quote=|via=}}</ref> - [https://www.sciencedirect.com/science/article/pii/S0198885915001809?via%3Dihub (Full Text)]
*2015, Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome<ref>{{Cite journal | last = Rajeevan | first = Mangalathu S. | author-link = Mangalathu Rajeevan | last2 = Dimulescu | first2 = Irina | authorlink2 = | last3 = Murray | first3 = Janna | authorlink3 = | last4 = Falkenberg | first4 = Virginia R. | authorlink4 = | last5 = Unger | first5 = Elizabeth R. | authorlink5 = Elizabeth Unger | date = 2015-08-01 | title = Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome | url =https://www.sciencedirect.com/science/article/pii/S0198885915001809|journal=Human Immunology|language=en|volume=76|issue=8 | pages = 553–560|doi=10.1016/j.humimm.2015.06.014|issn=0198-8859|quote=|via=}}</ref> - [https://www.sciencedirect.com/science/article/pii/S0198885915001809?via%3Dihub (Full Text)]
*2015, Early menopause and other gynecologic risk indicators for chronic fatigue syndrome in women<ref>{{Cite journal|last=Boneva|first=Roumiana S.|author-link=|last2=Lin|first2=Jin-Mann S.|author-link2=|last3=Unger|first3=Elizabeth R.|author-link3=|date=Aug 2015|title=Early menopause and other gynecologic risk indicators for chronic fatigue syndrome in women|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745581/|journal=Menopause (New York, N.Y.)|volume=22|issue=8|pages=826–834|doi=10.1097/GME.0000000000000411|issn=1072-3714|pmc=5745581|pmid=25647777|access-date=|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745581/ (Full Text)]
*2015, Early menopause and other gynecologic risk indicators for chronic fatigue syndrome in women<ref>{{Cite journal | last = Boneva | first = Roumiana S. | author-link = | last2 = Lin | first2 = Jin-Mann S. | authorlink2 = | last3 = Unger | first3 = Elizabeth R. | authorlink3 = | date = Aug 2015 | title = Early menopause and other gynecologic risk indicators for chronic fatigue syndrome in women | url =https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745581/|journal=Menopause (New York, N.Y.)|volume=22|issue=8 | pages = 826–834|doi=10.1097/GME.0000000000000411|issn=1072-3714|pmc=5745581|pmid=25647777|access-date=|quote=|via=}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745581/ (Full Text)]
*2016, [[Telomere shortening|Telomere Length Analysis]] in Chronic Fatigue Syndrome<ref name="UngerER, 2016" /> - [http://www.fasebj.org/content/30/1_Supplement/lb459.abstract?sid=5f767750-e4c9-4d63-955a-364457766ce1 (Full Text)]  
*2016, [[Telomere shortening|Telomere Length Analysis]] in Chronic Fatigue Syndrome<ref name="UngerER, 2016" /> - [http://www.fasebj.org/content/30/1_Supplement/lb459.abstract?sid=5f767750-e4c9-4d63-955a-364457766ce1 (Full Text)]  
*2016, [[CDC]] Grand Rounds: [[Chronic Fatigue Syndrome]] — Advancing Research and Clinical Education. Morbidity and [[Mortality]] Weekly Report<ref>{{Cite journal|last1=Unger|first1=ER|authorlink1=Elizabeth Unger|last2=Lin|first2=JS|authorlink2=Jin-Mann Sally Lin|last3=Brimmer|first3=DJ|authorlink3=|last4=Lapp|first4=CW|authorlink4=Charles Lapp|last5=Komaroff|first5=AL|authorlink5=Anthony Komaroff|last6=Nath|first6=A|authorlink6=Avindra Nath|last7=Laird|first7=S|authorlink7=| last8=Iskander|first8=J|authorlink8=John Iskander|title=CDC Grand Rounds: Chronic Fatigue Syndrome — Advancing Research and Clinical Education|journal=Morbidity and Mortality Weekly Report|volume=65|issue=5051|page=1434–1438|date=2016|doi=10.15585/mmwr.mm655051a4}} - </ref> - [https://www.cdc.gov/mmwr/volumes/65/wr/mm655051a4.htm (Full Text)]
*2016, [[CDC]] Grand Rounds: [[Chronic Fatigue Syndrome]] — Advancing Research and Clinical Education. Morbidity and [[Mortality]] Weekly Report<ref>{{Cite journal | last1 = Unger | first1 = ER | authorlink = Elizabeth Unger | last2 = Lin | first2 = JS | authorlink2 = Jin-Mann Sally Lin | last3 = Brimmer | first3 = DJ | authorlink3 = | last4 = Lapp | first4 = CW | authorlink4 = Charles Lapp | last5 = Komaroff | first5 = AL | authorlink5 = Anthony Komaroff | last6 = Nath | first6 = A | author-link6 = Avindra Nath | last7 = Laird | first7 = S | author-link7 = | last8 = Iskander | first8 = J | author-link8 = John Iskander | title = CDC Grand Rounds: Chronic Fatigue Syndrome — Advancing Research and Clinical Education|journal=Morbidity and Mortality Weekly Report|volume=65|issue=5051 | page = 1434–1438 | date = 2016 | doi=10.15585/mmwr.mm655051a4}} - </ref> - [https://www.cdc.gov/mmwr/volumes/65/wr/mm655051a4.htm (Full Text)]
*2016, [[CDC Multi-site Clinical Assessment of CFS]]
*2016, [[CDC Multi-site Clinical Assessment of CFS]]
*2016, Methods of applying the 1994 case definition of chronic fatigue syndrome - impact on classification and observed illness characteristics - [https://www.researchgate.net/profile/Roumiana_Boneva/publication/297892752_Methods_of_applying_the_1994_case_definition_of_chronic_fatigue_syndrome_-_impact_on_classification_and_observed_illness_characteristics/links/56efde2c08aeae9f93e7f5e4.pdf?origin=publication_detail (Full Text)]
*2016, Methods of applying the 1994 case definition of chronic fatigue syndrome - impact on classification and observed illness characteristics - [https://www.researchgate.net/profile/Roumiana_Boneva/publication/297892752_Methods_of_applying_the_1994_case_definition_of_chronic_fatigue_syndrome_-_impact_on_classification_and_observed_illness_characteristics/links/56efde2c08aeae9f93e7f5e4.pdf?origin=publication_detail (Full Text)]
*2017, Multi-Site Clinical Assessment of [[ME/CFS|Myalgic Encephalomyelitis/Chronic Fatigue Syndrome]] (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study<ref name="Unger, 2017" /> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565838/ (Full Text)]
*2017, Multi-Site Clinical Assessment of [[ME/CFS|Myalgic Encephalomyelitis/Chronic Fatigue Syndrome]] (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study<ref name="Unger, 2017" /> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565838/ (Full Text)]
*2018, A Common Language for Clinical Research Studies: The National Institute of Neurological Disorders and Stroke (NINDS) and Centers for Disease Control and Prevention (CDC) Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Common Data Elements (CDEs)<ref name="Feldman2018&quot;">{{Cite journal|title = Common Language for Clinical Research Studies: The National Institute of Neurological Disorders and Stroke (NINDS) and Centers for Disease Control and Prevention (CDC) Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Common Data Elements (CDEs)|url=http://n.neurology.org/content/90/15_Supplement/P2.016|first=|last= |authorlink=|first2=|last2 =|author-link2=|last3=|journal =Neurology|date= April 10, 2018|volume = 90|issue =15 Supplement|pages=|quote=|via=|vauthors=Feldman R, Gay K, Ala'i S, Esterlitz J, Sheikh M, Tanveer S, Joseph K, Unger E, Whittemore V}}</ref> - [http://n.neurology.org/content/90/15_Supplement/P2.016 (Abstract)]
*2018, A Common Language for Clinical Research Studies: The National Institute of Neurological Disorders and Stroke (NINDS) and Centers for Disease Control and Prevention (CDC) Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Common Data Elements (CDEs)<ref name="Feldman2018&quot;">{{Cite journal| title = Common Language for Clinical Research Studies: The National Institute of Neurological Disorders and Stroke (NINDS) and Centers for Disease Control and Prevention (CDC) Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Common Data Elements (CDEs)| url = http://n.neurology.org/content/90/15_Supplement/P2.016 | first = | last = | authorlink = | first2 = | last2 = | authorlink2 = | last3 = |journal =Neurology | date = April 10, 2018|volume = 90|issue =15 Supplement | pages = |quote=|via=|vauthors=Feldman R, Gay K, Ala'i S, Esterlitz J, Sheikh M, Tanveer S, Joseph K, Unger E, Whittemore V}}</ref> - [http://n.neurology.org/content/90/15_Supplement/P2.016 (Abstract)]
*2019, Assessment of ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome): A Case Study for Health Care Providers<ref>{{Cite journal|last=Brimmer|first=Dana|last2=Jones|first2=James|last3=Boneva|first3=Roumiana|last4=Campbell|first4=Charlotte|last5=Lin|first5=Jin-Mann|author-link5=Jin-Mann Sally Lin|last6=Unger|first6=Elizabeth|author-link6=Elizabeth Unger|date=2016|title=Assessment of ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome): A Case Study for Health Care Providers|url=https://www.mededportal.org/publication/10527|journal=MedEdPORTAL Publications|volume=12|doi=10.15766/mep_2374-8265.10527|pmc=|pmid=30984868}}</ref> - [https://www.mededportal.org/publication/10527/ (Full text)]
*2019, Assessment of ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome): A Case Study for Health Care Providers<ref>{{Cite journal | last = Brimmer | first = Dana | last2 = Jones | first2 = James | last3 = Boneva | first3 = Roumiana | last4 = Campbell | first4 = Charlotte | last5 = Lin | first5 = Jin-Mann | authorlink5 = Jin-Mann Sally Lin | last6 = Unger | first6 = Elizabeth | author-link6 = Elizabeth Unger | date = 2016 | title=Assessment of ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome): A Case Study for Health Care Providers |url =https://www.mededportal.org/publication/10527|journal=MedEdPORTAL Publications|volume=12|doi=10.15766/mep_2374-8265.10527|pmc=|pmid=30984868}}</ref> - [https://www.mededportal.org/publication/10527/ (Full text)]
* 2019, Endometriosis as a Comorbid Condition in Chronic Fatigue Syndrome (CFS):  Secondary Analysis of Data from a CFS Case-Control study<ref>{{Cite journal|last=Boneva|first=Roumiana S.|author-link=|last2=Lin|first2=Jin-Mann S.|author-link2=Jin-Mann Sally Lin|last3=Wieser|first3=Friedrich|author-link3=|last4=Nater|first4=Urs M.|author-link4=|last5=Ditzen|first5=Beate|author-link5=|last6=Taylor|first6=Robert N.|author-link6=|last7=Unger|first7=Elizabeth R.|author-link7=Elizabeth Unger|date=Apr 2018|title=Endometriosis as a Comorbid Condition in Chronic Fatigue Syndrome (CFS): Secondary Analysis of Data from a CFS Case-Control study|url=https://www.frontiersin.org/articles/10.3389/fped.2019.00195/abstract|journal=Frontiers in Pediatrics|volume=|issue=|pages=|doi=10.3389/fped.2019.00195|quote=|via=}}</ref> - [https://www.frontiersin.org/articles/10.3389/fped.2019.00195/abstract (Abstract)]
* 2019, Endometriosis as a Comorbid Condition in Chronic Fatigue Syndrome (CFS):  Secondary Analysis of Data from a CFS Case-Control study<ref>{{Cite journal | last = Boneva | first = Roumiana S. | author-link = | last2 = Lin | first2 = Jin-Mann S. | authorlink2 = Jin-Mann Sally Lin | last3 = Wieser | first3 = Friedrich | authorlink3 = | last4 = Nater | first4 = Urs M. | authorlink4 = | last5 = Ditzen | first5 = Beate | authorlink5 = | last6 = Taylor | first6 = Robert N. | author-link6 = | last7 = Unger | first7 = Elizabeth R. | author-link8 = Elizabeth Unger | date = Apr 2018 | title = Endometriosis as a Comorbid Condition in Chronic Fatigue Syndrome (CFS): Secondary Analysis of Data from a CFS Case-Control study| url = https://www.frontiersin.org/articles/10.3389/fped.2019.00195/abstract|journal=Frontiers in Pediatrics|volume=|issue= | pages = |doi=10.3389/fped.2019.00195|quote=|via=}}</ref> - [https://www.frontiersin.org/articles/10.3389/fped.2019.00195/abstract (Abstract)]


==Talks and interviews==
==Talks and interviews==
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::[https://www.cdc.gov/grand-rounds/pp/2016/20160216-chronic-fatigue.html Grand Rounds Video]
::[https://www.cdc.gov/grand-rounds/pp/2016/20160216-chronic-fatigue.html Grand Rounds Video]
::[https://www.cdc.gov/grand-rounds/pp/2016/20160216-presentation-chronic-fatigue-H.pdf Grand Rounds Presentation Slide Deck]
::[https://www.cdc.gov/grand-rounds/pp/2016/20160216-presentation-chronic-fatigue-H.pdf Grand Rounds Presentation Slide Deck]
*2019, [https://www.me-pedia.org/index.php?title=Elizabeth_Unger&action=edit Chronic Fatigue Syndrome: It's Real, and We Can Do Better]<ref>{{Cite web|url=https://login.medscape.com/login/sso/getlogin?urlCache=aHR0cHM6Ly93d3cubWVkc2NhcGUuY29tL3ZpZXdhcnRpY2xlLzkwODYyMj9zcmM9cnNz&ac=401|title=Chronic Fatigue Syndrome: It's Real, and We Can Do Better|last=|first=|authorlink=Elizabeth Unger|date=Feb 25, 2019|website=medscape.com|archive-url=|archive-date=|url-status=|access-date=2019-02-25}}</ref>
*2019, [https://www.me-pedia.org/index.php?title=Elizabeth_Unger&action=edit Chronic Fatigue Syndrome: It's Real, and We Can Do Better]<ref>{{Cite web | url=https://login.medscape.com/login/sso/getlogin?urlCache=aHR0cHM6Ly93d3cubWVkc2NhcGUuY29tL3ZpZXdhcnRpY2xlLzkwODYyMj9zcmM9cnNz&ac=401 | title = Chronic Fatigue Syndrome: It's Real, and We Can Do Better | last = | first = | authorlink = Elizabeth Unger | date = Feb 25, 2019 | website = medscape.com|archive-url=|archive-date=|url-status=|access-date=2019-02-25}}</ref>
*2019, Speaker at the 14th [[Invest in ME International ME Conference]] - ''Speech title: ME Research Update at Centers for Disease Control''<ref>{{Cite web|url=http://www.investinme.org/IIMEC14.shtml|title=Invest in ME Research - IIMEC14 14th Invest in ME Reseaerch International ME Conference 2019|website=[[Invest in ME Research]]|access-date=2020-02-26}}</ref> ''-'' [https://www.youtube.com/watch?v=9J0w1Gom3Wc (Video)]
*2019, Speaker at the 14th [[Invest in ME International ME Conference]] - ''Speech title: ME Research Update at Centers for Disease Control''<ref>{{Cite web | url=http://www.investinme.org/IIMEC14.shtml | title = IIMEC14 14th Invest in ME Reseaerch International ME Conference 2019 | website = [[Invest in ME Research]]|access-date=2020-02-26}}</ref> ''-'' [https://www.youtube.com/watch?v=9J0w1Gom3Wc (Video)]




Line 67: Line 67:
==References==
==References==
<references>
<references>
<ref name="Fischer, 2014">{{Cite journal |last1   = Fischer |first            1  |authorlink1 = |last2   = William |first            2  |authorlink2 = |last3   = Strauss |first            3  |authorlink3 = |last4   = Unger |first              4  |authorlink4 = Elizabeth Unger |last5   = Jason |first              5  |authorlink5 = Leonard Jason |last6   = Marshall, Jr |first      6  |authorlink6 = Gailen Marshall |last7   = Dimitrakoff |first        7  |authorlink7 = Jordan Dimitrakoff  
<ref name="Fischer, 2014">{{Cite journal | last1 = Fischer | first1 = David B. | author-link1 = | last2 = William | first2 = Arsani H. | authorlink2 = | last3 = Strauss | first3 = Adam C. | authorlink3 = | last4 = Unger | first4 = Elizabeth R. | authorlink4 = Elizabeth Unger | last5 = Jason | first5 = Leonard | authorlink5 = Leonard Jason | last6 = Marshall, Jr | first6 = Gailen D. | author-link6 = Gailen Marshall | last7 = Dimitrakoff | first7 = Jordan D. | author-link8 = Jordan Dimitrakoff | title = Chronic Fatigue Syndrome: The Current Status and Future Potentials of Emerging Biomarkers | journal = Fatigue: Biomedicine, Health & Behavior | volume = 2 | issue = 2 | page = 93-109 | date = 2014 | pmid = | doi = 10.1080/21641846.2014.906066 }}</ref>
| title   = Chronic Fatigue Syndrome: The Current Status and Future Potentials of Emerging Biomarkers
<ref name="Jason,Unger 2012">{{Cite journal | last1 = Jason | first1 = LA | author-link1 = Leonard Jason | last2 = Unger | first2 = ER | authorlink2 = Elizabeth Unger | last3 = Dimitrakoff | first3 = JD | authorlink3 = Jordan Dimitrakoff | last4 = Fagin | first4 = AP | authorlink4 = | last5 = Houghton | first5 = M | authorlink5 = Michael Houghton | last6 = Cook | first6 = DB | author-link6 = Dane Cook | last7 = Marshall | first7 = GD, Jr | author-link8 = Gailen Marshall | last8 = Klimas | first8 = N | author-link8 = Nancy Klimas | last9 = Snell | first9 = C | author-link9 = Christopher Snell | title = Minimum data elements for research reports on CFS | journal = Brain, Behavior, Immunology | volume = 26 | issue = 3 | page = 401-6 | date = 2012 | pmid = 22306456 | doi = 10.1016/j.bbi.2012.01.014 }}</ref>
| journal = Fatigue: Biomedicine, Health & Behavior   | volume = 2   | issue = 2   | page = 93-109
<ref name="Majer, 2007">{{Cite journal | last1 = Majer | first1 = M | author-link1 = | last2 = Jones | first2 = JF | authorlink2 = | last3 = Unger | first3 = E | authorlink3 = Elizabeth Unger | last4 = Youngblood | first4 = LS | authorlink4 = | last5 = Decker | first5 = MJ | authorlink5 = | last6 = Gurbaxani | first6 = B | author-link6 = | last7 = Heim | first7 = C | author-link7 = | last8 = Reeves | first8 = WC | author-link8 = William Reeves | title = Perception versus polysomnographic assessment of sleep in CFS and non-fatigued control subjects: results from a population-based study | journal = BMC Neurology | volume = 7 | issue = 40 | page = | date = 2007 | pmid = 18053240 | doi = 10.1186/1471-2377-7-40 }}</ref>
| date   = 2014
<ref name="Nisenbaum, 2004">{{Cite journal | last1 = Nisenbaum | first1 = R | author-link1 =Rosane Nisenbaum | last2 = Reyes | first2 = M | authorlink2 = | last3 = Unger | first3 = ER | authorlink3 = Elizabeth Unger | last4 = Reeves | first4 = W | authorlink4 = William Reeves | title = Factor analysis of symptoms among subjects with unexplained chronic fatigue: what can we learn about chronic fatigue syndrome? | journal = J Psychosom Res. | volume = 56 | issue = 2 | page = 171-8 | date =Feb 2004 | pmid = 15016574 | doi = 10.1016/S0022-3999(03)00039-4 }}</ref>
| pmid   =  
| doi     = 10.1080/21641846.2014.906066
}}
</ref>
<ref name="Jason,Unger 2012">{{Cite journal |last1   = Jason |first              1  |authorlink1 = Leonard Jason |last2   = Unger |first              2  |authorlink2 = Elizabeth Unger |last3   = Dimitrakoff |first        3  |authorlink3 = Jordan Dimitrakoff |last4   = Fagin |first              4  |authorlink4 = |last5   = Houghton |first          5  |authorlink5 = Michael Houghton |last6   = Cook |first              6  |authorlink6 = Dane Cook |last7   = Marshall |first          7  |authorlink7 = Gailen Marshall |last8   = Klimas |first            8  |authorlink8 = Nancy Klimas |last9   = Snell |first              9  |authorlink9 = Christopher Snell
| title   = Minimum data elements for research reports on CFS
| journal = Brain, Behavior, Immunology   | volume = 26   | issue = 3   | page = 401-6
| date   = 2012  
| pmid   = 22306456
| doi     = 10.1016/j.bbi.2012.01.014
}}
</ref>
<ref name="Majer, 2007">{{Cite journal
| last1   = Majer             | first1 = M | authorlink1 =  
| last2   = Jones             | first2 = JF | authorlink2 =  
| last3   = Unger             | first3 = E | authorlink3 = Elizabeth Unger  
| last4   = Youngblood       | first4 = LS | authorlink4 =  
| last5   = Decker           | first5 = MJ | authorlink5 =  
| last6   = Gurbaxani         | first6 = B | authorlink6 =  
| last7   = Heim             | first7 = C | authorlink7 =  
| last8   = Reeves           | first8 = WC | authorlink8 = William Reeves
| title   = Perception versus polysomnographic assessment of sleep in CFS and non-fatigued control subjects: results from a population-based study
| journal = BMC Neurology   | volume = 7   | issue = 40   | page =  
| date   = 2007
| pmid   = 18053240
| doi     = 10.1186/1471-2377-7-40
}}
</ref>
<ref name="Nisenbaum, 2004">{{Cite journal
| last1   = Nisenbaum         | first1 = R | authorlink1 =Rosane Nisenbaum  
| last2   = Reyes             | first2 = M | authorlink2 =  
| last3   = Unger             | first3 = ER | authorlink3 = Elizabeth Unger
| last4   = Reeves           | first4 = W | authorlink4 = William Reeves
| title   = Factor analysis of symptoms among subjects with unexplained chronic fatigue: what can we learn about chronic fatigue syndrome?
| journal = J Psychosom Res.   | volume = 56   | issue = 2   | page = 171-8
| date   = Feb 2004
| pmid   = 15016574
| doi     = 10.1016/S0022-3999(03)00039-4
}}
</ref>


<ref name="Reeves,2006">{{Cite journal |last1   = Reeves |first            1  |authorlink1 = William Reeves
<ref name="Reeves,2006">{{Cite journal | last1 = Reeves | first1 = W.C. | author-link1 = William Reeves | last2 = Heim | first2 = C. | authorlink2 = Christine Heim | last3 = Maloney | first3 = E.M. | author-link3 = | last4 = Youngblood | first4 = L.S. | authorlink4 = | last5 = Unger | first5 = E.R. | authorlink5 = Elizabeth Unger | last6 = Decker | first6 = M.J. | author-link6 = | last7 = Jones | first7 = J.F. |author-link8 = James Jones | last8 = Rye | first8 =D.B. |author-link8 =  | title = Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study | journal = BMC Neurology | volume = 6 | issue = 41 | date = 2006 | doi = 10.1186/1471-2377-6-41 }}</ref>
| last2   = Heim               | first2 = C. | authorlink2 = Christine Heim |last3   = Maloney |first            3  |authorlink3 = |last4   = Youngblood |first        4  |authorlink4 = |last5   = Unger |first              5  |authorlink5 = Elizabeth Unger |last6   = Decker |first            6  |authorlink6 = |last7   = Jones |first              7  |authorlink7 = James Jones |last8   = Rye |first                8  |authorlink8 =   
<ref name="Unger, 2017">{{Citation | last1 = Unger | first1 = Elizabeth R. | author-link1 = Elizabeth Unger | last2 = Lin | first2 = Jin-Mann S. | authorlink2 = Jin-Mann Sally Lin | last3 = Tian | first3 = Hao | authorlink3 = Hao Tian | last4 = Natelson | first4 = Benjamin H | authorlink4 = Benjamin Natelson | last5 = Lange | first5 = Gudrun | authorlink5 = Gudrun Lange | last6 = Vu | first6 = Diana | author-link6 = Diana Vu | last7 = Blate | first7 = Michelle | author-link8 = Michelle Blste | last8 = Klimas | first8 = Nancy G. | author-link8 = Nancy Klimas | last9 = Balbin | first9 = Elizabeth G. | author-link9 = Elizabeth Bslbin | last10 = Bateman | first10 = Lucinda | author-link10 = Lucinda Bateman | last11 = Allen | first11 = Ali | author-link11 = Ali Allen | last12 = Lapp | first12 = Charles W. | author-link12 = Charles Lapp | last13 = Springs | first13 = Wendy | author-link13 = Wendy Springs | last14 = Kogelnik | first14 = Andreas M. | author-link14 = Andreas Kogelnik | last15 = Phan | first15 = Catrina C. | author-link15 = Catrina Phan | last16 = Danver | first16 = Joan | author-link16 = Joan Danver | last17 = Podell | first17 = Richard N. | author-link17 = Richard Podell | last18 = Fitzpatrick | first18 = Trisha | author-link18 = Trisha Fitzpatrick | last19 = Peterson | first19 = Daniel L. | author-link19 = Daniel Peterson | last20 = Gottschalk | first20 = C. Gunnar | authorlink20 = Gunnar Gottschalk | last21 = Rajeevan | first21 = Mangalathu S. | authorlink21 = Mangalathu Rajeevan | last22 = MCAM Study Group | title = Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study. | journal = American Journal of Epidemiology | volume = 1-10 | issue = | page = | date = 2017 | pmid = | doi = 10.1093/aje/kwx029 }}</ref>
| title   = Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study
<ref name="UngerER, 2016">{{Cite journal | last1 = Unger | first1 = ER | author-link1 = Elizabeth Unger | last2 = Murray | first2 = J | authorlink2 = | last3 = Oakley | first3 = LP | authorlink3 = | last4 = Lin | first4 = JM | authorlink4 = Jin-Mann Sally Lin | last5 = Rajeevan | first5 = MS | authorlink5 = | title = Telomere Length Analysis in Chronic Fatigue Syndrome | journal = The FASEB Journal | volume = 30 | issue = 1 | page = lb459 | date = 2016 | pmid = | url = http://www.fasebj.org/content/30/1_Supplement/lb459.abstract?sid=5f767750-e4c9-4d63-955a-364457766ce1 }}</ref>
| journal = BMC Neurology   | volume = 6   | issue = 41  
<ref name="Wagner, 2005">{{Cite journal | last1 = Wagner | first1 = Dieter | author-link1 =Dieter Wagner | last2 = Nisenbaum | first2 = Rosane | authorlink2 =Rosane Nisenbaum | last3 = Heim | first3 = Christine | authorlink3 =Christine Heim | last4 = Jones | first4 = James F. | authorlink4 = James Jones | last5 = Unger | first5 = Elizabeth R. | authorlink5 = Elizabeth Unger | last6 = Reeves | first6 = William C. | author-link6 = William Reeves | title = Psychometric properties of the CDC Symptom Inventory for assessment of Chronic Fatigue Syndrome. | journal = Population Health Metrics | volume = 3 | issue = 8 | page = 1 | date = 2005 | doi = 10.1186/1478-7954-3-8 }}</ref>
| date   = 2006
| doi     = 10.1186/1471-2377-6-41
}}
</ref>
<ref name="Unger, 2017">{{Citation |last1   = Unger |first        1  |authorlink1 = Elizabeth Unger |last2   = Lin |first          2  |authorlink2 = Jin-Mann Sally Lin |last3   = Tian |first        3  |authorlink3 = Hao Tian |last4   = Natelson |first    4  |authorlink4 = Benjamin Natelson |last5   = Lange |first        5  |authorlink5 = Gudrun Lange |last6   = Vu |first          6  |authorlink6 = Diana Vu |last7   = Blate |first        7  |authorlink7 = Michelle Blste |last8   = Klimas |first      8  |authorlink8 = Nancy Klimas   |last9   = Balbin |first      9  |authorlink9 = Elizabeth Bslbin |last10 = Bateman |first      10  |authorlink10 = Lucinda Bateman |last11 = Allen |first        11  |authorlink11 = Ali Allen |last12 = Lapp |first        12  |authorlink12 = Charles Lapp |last13 = Springs |first      13  |authorlink13 = Wendy Springs |last14 = Kogelnik |first    14  |authorlink14 = Andreas Kogelnik |last15 = Phan |first        15  |authorlink15 = Catrina Phan |last16 = Danver |first      16  |authorlink16 = Joan Danver |last17 = Podell |first      17  |authorlink17 = Richard Podell  
| last18 = Fitzpatrick | first18 = Trisha         | authorlink18 = Trisha Fitzpatrick |last19 = Peterson |first    19  |authorlink19 = Daniel Peterson  
| last20 = Gottschalk   | first20 = C. Gunnar     | authorlink20 = Gunnar Gottschalk
| last21 = Rajeevan     | first21 = Mangalathu S. | authorlink21 = Mangalathu Rajeevan
| last22 = MCAM Study Group    
| title   = Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study.
| journal = American Journal of Epidemiology     | volume = 1-10   | issue =   | page =  
| date   = 2017
| pmid   =  
| doi     = 10.1093/aje/kwx029
}}
</ref>
<ref name="UngerER, 2016">{{Cite journal |last1   = Unger |first            1  |authorlink1 = Elizabeth Unger |last2   = Murray |first            2  |authorlink2 = |last3   = Oakley |first            3  |authorlink3 = |last4   = Lin |first              4  |authorlink4 = Jin-Mann Sally Lin |last5   = Rajeevan |first          5  |authorlink5 =  
| title   = Telomere Length Analysis in Chronic Fatigue Syndrome
| journal = The FASEB Journal   | volume = 30   | issue = 1   | page = lb459  
| date   = 2016
| pmid   =  
| url     = http://www.fasebj.org/content/30/1_Supplement/lb459.abstract?sid=5f767750-e4c9-4d63-955a-364457766ce1
}}
</ref>
<ref name="Wagner, 2005">{{Cite journal |last1   = Wagner |first            1  |authorlink1 =Dieter Wagner |last2   = Nisenbaum |first        2  |authorlink2 =Rosane Nisenbaum |last3   = Heim |first              3  |authorlink3 =Christine Heim |last4   = Jones |first            4  |authorlink4 =James Jones |last5   = Unger |first            5  |authorlink5 = Elizabeth Unger |last6   = Reeves |first            6  |authorlink6 = William Reeves
| title   = Psychometric properties of the CDC Symptom Inventory for assessment of Chronic Fatigue Syndrome.
| journal = Population Health Metrics   | volume = 3   | issue = 8   | page = 1
| date   = 2005
| doi     = 10.1186/1478-7954-3-8
}}
</ref>
</references>
</references>
[[Category:US researchers]]
[[Category:US researchers]]
[[Category:Centers for Disease Control and Prevention officials]]
[[Category:Centers for Disease Control and Prevention officials]]
[[Category:NIH post-infectious ME/CFS study investigator]]
[[Category:NIH post-infectious ME/CFS study investigator]]

Latest revision as of 20:03, July 29, 2023

Beth-Unger.jpg

Elizabeth (Beth) R. Unger, MD, PhD, is the Chief of the Chronic Viral Disease Branch (CVDB), Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases at the Centers for Disease Control and Prevention (CDC), Atlanta, Georgia. chronic fatigue syndrome (CFS) research falls under her department. She has worked at the CDC since 1997 and replaced Dr. William Reeves as Chief of CVDB in 2010.[1] Dr. Unger has done extensive research at the CDC on the human papillomavirus (HPV).

In 2002-2003, Dr Unger was on the team that tested the validity of 1994 CDC case definition of CFS, known as the empirical definition or Fukuda criteria, via the Wichita Clinical Study. The study, according to the CDC, "identifies persons with CFS in a precise manner that can be readily reproduced by both investigators and clinicians."[2][3] Many researchers continued to use the Fukuda criteria for research.

Chronic Fatigue Syndrome Advisory Committee[edit | edit source]

Dr. Unger has represented the Centers for Disease Control and Prevention (CDC) on the Chronic Fatigue Syndrome Advisory Committee (CFSAC), for the U.S. Department of Health and Human Services as an Ex Officio Member.

Education[edit | edit source]

Dr. Unger received an undergraduate degree in chemistry at Lebanon Valley College, Annville, PA and her PhD and MD in the Division of Biologic Sciences at the University of Chicago. Her residency and fellowship was completed at Pennsylvania State University Medical Center.[1]

Awards[edit | edit source]

Notable publications related to ME/CFS[edit | edit source]

  • 2003, Prevalence and Incidence of Chronic Fatigue Syndrome in Wichita, Kansas - (Full Text)
  • 2003, Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution[4] - (Full Text)
  • 2004, Factor analysis of symptoms among subjects with unexplained chronic fatigue: what can we learn about chronic fatigue syndrome?[5] - (Abstract)
  • 2005, Chronic Fatigue Syndrome – A clinically empirical approach to its definition and study.[3]
  • 2005, Psychometric properties of the CDC Symptom Inventory for assessment of Chronic Fatigue Syndrome[6] - (Full Text)
  • 2006, Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study[7] - (Full Text)
  • 2007, Perception versus polysomnographic assessment of sleep in CFS and non-fatigued control subjects: results from a population-based study[8] - (Full Text)
  • 2009, An evaluation of exclusionary medical/psychiatric conditions in the definition of chronic fatigue syndrome[9] - (Full Text)
  • 2012, Minimum data elements for research reports on CFS[10] - (Full text)
  • 2013, Acute psychosocial stress-mediated changes in the expression and methylation of perforin in chronic fatigue syndrome[11] - (Full Text)
  • 2014, Chronic Fatigue Syndrome: The Current Status and Future Potentials of Emerging Biomarkers[12] - (Full Text)
  • 2014, Decreased basal ganglia activation in subjects with chronic fatigue syndrome: association with symptoms of fatigue[13] - (Full Text)
  • 2015, Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome[14] - (Full Text)
  • 2015, Early menopause and other gynecologic risk indicators for chronic fatigue syndrome in women[15] - (Full Text)
  • 2016, Telomere Length Analysis in Chronic Fatigue Syndrome[16] - (Full Text)
  • 2016, CDC Grand Rounds: Chronic Fatigue Syndrome — Advancing Research and Clinical Education. Morbidity and Mortality Weekly Report[17] - (Full Text)
  • 2016, CDC Multi-site Clinical Assessment of CFS
  • 2016, Methods of applying the 1994 case definition of chronic fatigue syndrome - impact on classification and observed illness characteristics - (Full Text)
  • 2017, Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study[18] - (Full Text)
  • 2018, A Common Language for Clinical Research Studies: The National Institute of Neurological Disorders and Stroke (NINDS) and Centers for Disease Control and Prevention (CDC) Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Common Data Elements (CDEs)[19] - (Abstract)
  • 2019, Assessment of ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome): A Case Study for Health Care Providers[20] - (Full text)
  • 2019, Endometriosis as a Comorbid Condition in Chronic Fatigue Syndrome (CFS): Secondary Analysis of Data from a CFS Case-Control study[21] - (Abstract)

Talks and interviews[edit | edit source]

Grand Rounds Video
Grand Rounds Presentation Slide Deck


Online presence[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome". Centers for Disease Control and Prevention. August 8, 2019. Retrieved September 3, 2019.
  2. http://www.cdc.gov/cfs/case-definition/1994.html
  3. 3.0 3.1 Reeves, William C.; Wagner, Dieter; Nisenbaum, Rosane; Jones, James F.; Gurbaxani, Brian; Solomon, Laura; Papanicolaou, Dimitris A.; Unger, Elizabeth R.; Vernon, Suzanne D.; Heim, Christine (December 15, 2005). "Chronic Fatigue Syndrome – A clinically empirical approach to its definition and study". BMC Medicine. 3 (1): 19. doi:10.1186/1741-7015-3-19. ISSN 1741-7015. PMC 1334212. PMID 16356178.
  4. Reeves, W.C.; Lloyd, A.; Vernon, S.D.; Klimas, N.; Jason, L.A.; Bleijenberg, G.; Evengard, B.; White, P.D.; Nisenbaum, R.; Unger, E. (2003), "Identification of ambiguities in the 1994 chronic fatigue syndrome research case definition and recommendations for resolution", BMC Health Services Research, 3 (25), doi:10.1186/1472-6963-3-25
  5. Nisenbaum, R; Reyes, M; Unger, ER; Reeves, W (February 2004). "Factor analysis of symptoms among subjects with unexplained chronic fatigue: what can we learn about chronic fatigue syndrome?". J Psychosom Res. 56 (2): 171-8. doi:10.1016/S0022-3999(03)00039-4. PMID 15016574.
  6. Wagner, Dieter; Nisenbaum, Rosane; Heim, Christine; Jones, James F.; Unger, Elizabeth R.; Reeves, William C. (2005). "Psychometric properties of the CDC Symptom Inventory for assessment of Chronic Fatigue Syndrome". Population Health Metrics. 3 (8): 1. doi:10.1186/1478-7954-3-8.
  7. Reeves, W.C.; Heim, C.; Maloney, E.M.; Youngblood, L.S.; Unger, E.R.; Decker, M.J.; Jones, J.F.; Rye, D.B. (2006). "Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study". BMC Neurology. 6 (41). doi:10.1186/1471-2377-6-41.
  8. Majer, M; Jones, JF; Unger, E; Youngblood, LS; Decker, MJ; Gurbaxani, B; Heim, C; Reeves, WC (2007). "Perception versus polysomnographic assessment of sleep in CFS and non-fatigued control subjects: results from a population-based study". BMC Neurology. 7 (40). doi:10.1186/1471-2377-7-40. PMID 18053240.
  9. Jones, James F; Lin, Jin-Mann S; Maloney, Elizabeth M; Boneva, Roumiana S; Nater, Urs M; Unger, Elizabeth R; Reeves, William C (December 2009). "An evaluation of exclusionary medical/psychiatric conditions in the definition of chronic fatigue syndrome". BMC Medicine. 7 (1). doi:10.1186/1741-7015-7-57. ISSN 1741-7015. PMC 2768736. PMID 19818157.
  10. Jason, LA; Unger, ER; Dimitrakoff, JD; Fagin, AP; Houghton, M; Cook, DB; Marshall, GD, Jr; Klimas, N; Snell, C (2012). "Minimum data elements for research reports on CFS". Brain, Behavior, Immunology. 26 (3): 401-6. doi:10.1016/j.bbi.2012.01.014. PMID 22306456.
  11. Falkenberg, Virginia R; Whistler, Toni; Murray, Janna R; Unger, Elizabeth R; Rajeevan, Mangalathu S (2013). "Acute Psychosocial Stress-Mediated Changes in the Expression and Methylation of Perforin in Chronic Fatigue Syndrome". Genetics and Epigenetics. 5: 1–9. doi:10.4137/GEG.S10944. PMC 4222335. PMID 25512702.
  12. Fischer, David B.; William, Arsani H.; Strauss, Adam C.; Unger, Elizabeth R.; Jason, Leonard; Marshall, Jr, Gailen D.; Dimitrakoff, Jordan D. (2014). "Chronic Fatigue Syndrome: The Current Status and Future Potentials of Emerging Biomarkers". Fatigue: Biomedicine, Health & Behavior. 2 (2): 93-109. doi:10.1080/21641846.2014.906066.
  13. Miller, Andrew H.; Jones, James F.; Drake, Daniel F.; Tian, Hao; Unger, Elizabeth R.; Pagnoni, Giuseppe (May 23, 2014). "Decreased Basal Ganglia Activation in Subjects with Chronic Fatigue Syndrome: Association with Symptoms of Fatigue". PLoS ONE. 9 (5): e98156. doi:10.1371/journal.pone.0098156. ISSN 1932-6203. PMC 4032274. PMID 24858857.
  14. Rajeevan, Mangalathu S.; Dimulescu, Irina; Murray, Janna; Falkenberg, Virginia R.; Unger, Elizabeth R. (August 1, 2015). "Pathway-focused genetic evaluation of immune and inflammation related genes with chronic fatigue syndrome". Human Immunology. 76 (8): 553–560. doi:10.1016/j.humimm.2015.06.014. ISSN 0198-8859.
  15. Boneva, Roumiana S.; Lin, Jin-Mann S.; Unger, Elizabeth R. (August 2015). "Early menopause and other gynecologic risk indicators for chronic fatigue syndrome in women". Menopause (New York, N.Y.). 22 (8): 826–834. doi:10.1097/GME.0000000000000411. ISSN 1072-3714. PMC 5745581. PMID 25647777.
  16. Unger, ER; Murray, J; Oakley, LP; Lin, JM; Rajeevan, MS (2016). "Telomere Length Analysis in Chronic Fatigue Syndrome". The FASEB Journal. 30 (1): lb459.
  17. Unger, ER; Lin, JS; Brimmer, DJ; Lapp, CW; Komaroff, AL; Nath, A; Laird, S; Iskander, J (2016). "CDC Grand Rounds: Chronic Fatigue Syndrome — Advancing Research and Clinical Education". Morbidity and Mortality Weekly Report. 65 (5051): 1434–1438. doi:10.15585/mmwr.mm655051a4. -
  18. Unger, Elizabeth R.; Lin, Jin-Mann S.; Tian, Hao; Natelson, Benjamin H; Lange, Gudrun; Vu, Diana; Blate, Michelle; Klimas, Nancy G.; Balbin, Elizabeth G.; Bateman, Lucinda; Allen, Ali; Lapp, Charles W.; Springs, Wendy; Kogelnik, Andreas M.; Phan, Catrina C.; Danver, Joan; Podell, Richard N.; Fitzpatrick, Trisha; Peterson, Daniel L.; Gottschalk, C. Gunnar; Rajeevan, Mangalathu S.; MCAM Study Group (2017), "Multi-Site Clinical Assessment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (MCAM): Design and Implementation of a Prospective/Retrospective Rolling Cohort Study.", American Journal of Epidemiology, 1–10, doi:10.1093/aje/kwx029
  19. Feldman R, Gay K, Ala'i S, Esterlitz J, Sheikh M, Tanveer S, Joseph K, Unger E, Whittemore V (April 10, 2018). "Common Language for Clinical Research Studies: The National Institute of Neurological Disorders and Stroke (NINDS) and Centers for Disease Control and Prevention (CDC) Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Common Data Elements (CDEs)". Neurology. 90 (15 Supplement).
  20. Brimmer, Dana; Jones, James; Boneva, Roumiana; Campbell, Charlotte; Lin, Jin-Mann; Unger, Elizabeth (2016). "Assessment of ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome): A Case Study for Health Care Providers". MedEdPORTAL Publications. 12. doi:10.15766/mep_2374-8265.10527. PMID 30984868.
  21. Boneva, Roumiana S.; Lin, Jin-Mann S.; Wieser, Friedrich; Nater, Urs M.; Ditzen, Beate; Taylor, Robert N.; Unger, Elizabeth R. (April 2018). "Endometriosis as a Comorbid Condition in Chronic Fatigue Syndrome (CFS): Secondary Analysis of Data from a CFS Case-Control study". Frontiers in Pediatrics. doi:10.3389/fped.2019.00195.
  22. "Chronic Fatigue Syndrome: It's Real, and We Can Do Better". medscape.com. February 25, 2019. Retrieved February 25, 2019.
  23. "IIMEC14 14th Invest in ME Reseaerch International ME Conference 2019". Invest in ME Research. Retrieved February 26, 2020.