Anonymous
Not logged in
Talk
Contributions
Create account
Log in
Search
Editing
Ehlers-Danlos syndrome
(section)
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Namespaces
Page
Discussion
More
More
Page actions
Read
Edit
Edit source
History
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
==Comorbidities & complications == ===ME/CFS === A 1999 case series by Dr. [[Peter Rowe]] of adolescents referred to his chronic fatigue syndrome clinic found 12 patients who also met the criteria for Ehlers-Danlos Syndrome and had orthostatic intolerance (postural orthostatic tachycardia or neurally-mediated hypotension). He concluded that βAmong patients with CFS and orthostatic intolerance, a subset also has EDS.β<ref name=":5">{{Cite journal | last = Rowe | first = Peter C. | last2 = Barron | first2 = Diana F. | last3 = Calkins | first3 = Hugh | last4 = Maumenee | first4 = Irene H. | last5 = Tong | first5 = Patrick Y. | last6 = Geraghty | first6 = Michael T. | date = 1999-10-01 | title = Orthostatic intolerance and chronic fatigue syndrome associated with Ehlers-Danlos syndrome | url =http://www.sciencedirect.com/science/article/pii/S0022347699701733|journal=The Journal of Pediatrics|volume=135|issue=4 | pages = 494β499|doi=10.1016/S0022-3476(99)70173-3|issn=0022-3476}}</ref> He also found joint hypermobility (Beighton score > 4) in 60% of pediatric ME/CFS patients viruses 24% of healthy controls.<ref name="Barron2002">{{Cite journal | last = Barron | first = Diana F. | last2 = Cohen | first2 = Bernard A. | last3 = Geraghty | first3 = Michael T. | last4 = Violand | first4 = Rick | last5 = Rowe | first5 = Peter C. | date = 2002-09-01 | title = Joint hypermobility is more common in children with chronic fatigue syndrome than in healthy controls |url =http://www.sciencedirect.com/science/article/pii/S0022347602001105|journal=The Journal of Pediatrics|volume=141|issue=3 | pages = 421β425|doi=10.1067/mpd.2002.127496|issn=0022-3476}}</ref> A 2022 study by Rowe found that hypermobility did not show any association with other clinical characteristics of ME/CFS, despite it being a risk factor for the development of ME/CFS.<ref>{{Cite journal | title = The Presentation of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Is Not Influenced by the Presence or Absence of Joint Hypermobility | date = Jan 2022| url = https://pubmed.ncbi.nlm.nih.gov/34537220/|journal=The Journal of Pediatrics|volume=240 | pages = 186β191.e2 | last = Vogel | first = Sarah K. | last2 = Primavera | first2 = Isabelle R. | last3 = Marden | first3 = Colleen L. | last4 = Jasion | first4 = Samantha E. | last5 = Cranston | first5 = Erica M. | last6 = Flaherty | first6 = Marissa A.K. | last7 = Violand | first7 = Richard L. | last8 = Rowe | first8 = Peter C.|doi=10.1016/j.jpeds.2021.09.014|pmid=34537220|issn=1097-6833}}</ref> A Swedish study of 234 ME/CFS patients meeting theΒ [[Canadian Consensus Criteria]] found that 49% of patients had hypermobility and 20% met the criteria for hEDS.<ref>{{Cite web | url = https://osf.io/qwn5h/|website=Center for Open Science|access-date=2019-12-03 | title = Bragee Bertilson et al. - ME CFS and Intracranial Hypertension | date = Nov 27, 2019 | last = | first = | authorlink = |archive-url=|archive-date=|url-status=}}</ref> === Other === * [[Dysautonomia]] * [[Mast cell activation syndrome]] * [[Postural orthostatic tachycardia syndrome]]<ref>{{Cite web | url = https://www.inspire.com/groups/ehlers-danlos-syndromes-and-related-disorders/discussion/the-ehlers-danlos-society-is-forming-a-comorbid-condition-coalition/ | title = The Ehlers-Danlos Society is forming a Comorbid Condition Coalition! - Inspire | last = | first = | date = Nov 8, 2017 | website = inspire.com| archive-url = | archive-date = |url-status = | access-date=2018-10-07}}</ref><ref>{{Cite news |url =http://www.thepainrelieffoundation.com/craniocervical-instability/ | title = What is Craniocervical Instability? - The Pain Relief Foundation|work=The Pain Relief Foundation|access-date=2018-10-07|language=en-US}}</ref><ref>{{Cite news |url =https://www.ehlers-danlos.com/2017-eds-classification-non-experts/neurological-spinal-manifestations-ehlers-danlos-syndromes/ | title = Neurological and Spinal Manifestations of the Ehlers-Danlos Syndromes (for Non-experts) {{!}} The Ehlers Danlos Society|work=The Ehlers Danlos Society|access-date=2018-10-07|language=en-US}}</ref> * [[Chiari malformation]]<ref name=":4">{{Cite journal | last = Henderson | first = Fraser C. | last2 = Austin | first2 = Claudiu | last3 = Benzel | first3 = Edward | last4 = Bolognese | first4 = Paolo | last5 = Ellenbogen | first5 = Richard | last6 = Francomano | first6 = Clair A. | last7 = Ireton | first7 = Candace | last8 = Klinge | first8 = Petra | last9 = Koby | first9 = Myles | date = 2017-02-21 | title = Neurological and spinal manifestations of the Ehlers-Danlos syndromes |url =https://onlinelibrary.wiley.com/doi/full/10.1002/ajmg.c.31549|journal=American Journal of Medical Genetics Part C: Seminars in Medical Genetics|language=en|volume=175|issue=1 | pages = 195β211|doi=10.1002/ajmg.c.31549|issn=1552-4868}}</ref> * [[Syringomyelia]]<ref name=":4" /> * [[Craniocervical instability]]<ref name=":4" /> * [[Atlantoaxial instability]]<ref name=":4" /> * [[Intracranial hypertension]]<ref name=":4" /> * [[Kyphosis]]<ref name=":4" /> and [[Scoliosis]]<ref name=":4" /> * [[Tethered cord syndrome]]<ref name=":4" /> * [[Dystonia]]<ref name=":4" /> * [[Tarlov cyst]]<ref name=":4" /> * [[prolapsed mitral valve|Mitral valve prolapse]]
Summary:
Please make sure your edits are consistent with
MEpedia's guidelines
.
By saving changes, you agree to the
Terms of use
, and you irrevocably agree to release your contribution under the
CC BY-SA 3.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)
Navigation
Navigation
Skip to content
Main page
Browse
Become an editor
Random page
Popular pages
Abbreviations
Glossary
About MEpedia
Links for editors
Contents
Guidelines
Recent changes
Pages in need
Search
Help
Wiki tools
Wiki tools
Special pages
Page tools
Page tools
User page tools
More
What links here
Related changes
Page information
Page logs