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[[File:DonaldLewis.png|right]] Dr '''Donald P. Lewis''' (died 29 July 2019) was a general practitioner specializing in ME/CFS in Melbourne, [[Australia]]. He had been treating patients with ME/CFS and researching the condition since his wife became ill with ME/CFS in 1985.<ref>{{Cite web | url = http://www.virology.ws/2019/08/19/trial-by-error-my-interview-with-melbournes-dr-don-lewis/ | title = Trial By Error: My Interview with Melbourne’s Dr Don Lewis|website=[[Virology blog]]|access-date=2019-08-21}}</ref> ==[[International Consensus Criteria]]== Dr Lewis is one of the authors of the 2011 case definition, [[International Consensus Criteria]].<ref>{{Cite journal | last = Carruthers | first = Bruce M. | authorlink = Bruce Carruthers | last2 = van de Sande | first2 = Marjorie I. | authorlink2 = Marjorie van de Sande | last3 = De Meirleir | first3 = Kenny L. | authorlink3 = Kenny De Meirleir | last4 = Klimas | first4 = Nancy G. | authorlink4 = Nancy Klimas | last5 = Broderick | first5 = Gordon | authorlink5 = Gordon Broderick | last6 = Mitchell | first6 = Terry | author-link6 = Terry Mitchell | last7 = Staines | first7 = Donald | author-link8 = Donald Staines | last8 = Powles | first8 = A.C. Peter | author-link8 = A C Peter Powles | last9 = Speight | first9 = Nigel | author-link9 = Nigel Speight | last10 = Vallings | first10 = Rosamund | author-link10 = Rosamund Vallings | last11 = Bateman | first11 = Lucinda | author-link11 = Lucinda Bateman | last12 = Baumgarten-Austrheim | first12 = Barbara | author-link12 = Barbara Baumgarten-Austrheim | last13 = Bell | first13 = David | author-link13 = David Bell | last14 = Carlo-Stella | first14 = Nicoletta | author-link14 = Nicoletta Carlo-Stella | last15 = Chia | first15 = John | author-link15 = John Chia | last16 = Darragh | first16 = Austin | author-link16 = Austin Darragh | last17 = Jo | first17 = Daehyun | author-link17 = Daehyun Jo | last18 = Lewis | first18 = Donald | author-link18 = Donald Lewis | last19 = Light | first19 = Alan | author-link19 = Alan Light | last20 = Marshall-Gradisnik | first20 = Sonya | author-link20 = Sonya Marshall-Gradisnik | last21 = Mena | first21 = Ismael | author-link21 = Ismael Mena | last22 = Mikovits | first22 = Judy | author-link22 = Judy Mikovits | last23 = Miwa | first23 = Kunihisa | author-link23 = Kunihisa Miwa | last24 = Murovska | first24 = Modra | author-link24 = Modra Murovska | last25 = Pall | first25 = Martin | author-link25 = Martin Pall | last26 = Stevens | first26 = Staci | author-link26 = Staci Stevens | date = 2011-08-22 | title=Myalgic encephalomyelitis: International Consensus Criteria | url = https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2796.2011.02428.x|journal=Journal of Internal Medicine|language=en|volume=270|issue=4 | pages = 327–338|doi=10.1111/j.1365-2796.2011.02428.x|issn=0954-6820|pmc=3427890|pmid=21777306|via=}}</ref> ==Books== *Chronic Fatigue Syndrome/ME: Turning Disability Towards Ability (2003) *2017, Chapter 31 - Sleep, Cognitive and Mood Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, in ''The Handbook of Stress and Health: A Guide to Research and Practice''<ref name="Wallis, book, 2017" /> ==Notable studies== *2009, Increased [[Lactic acid|d-lactic Acid]] intestinal bacteria in patients with chronic fatigue syndrome<ref name="Sheedy2009" /> *2014, Comorbidity of [[postural orthostatic tachycardia syndrome]] and chronic fatigue syndrome in an Australian cohort<ref name="Reynolds2014" /> *2015, Sleep quality and the treatment of intestinal microbiota imbalance in Chronic Fatigue Syndrome: A pilot study<ref name="Jackson2015" /> - [http://www.sciencedirect.com/science/article/pii/S1984006315000632 (Full text)] *2015, Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients<ref name="Armstrong, 2015" /> *2016, Widespread pain and altered renal function in ME/CFS patients<ref>{{Cite journal | last = McGregor | first = Neil R. | authorlink = Neil McGregor | last2 = Armstrong | first2 = Christopher W. | authorlink2 = Christopher Armstrong | last3 = Lewis | first3 = Donald P. | authorlink3 = Donald Lewis | last4 = Butt | first4 = Henry L. | authorlink4 = Henry Butt | last5 = Gooley | first5 = Paul R. | authorlink5 = Paul Gooley | date = Jul 2016 | title = Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients |url =https://www.tandfonline.com/doi/abs/10.1080/21641846.2016.1207400?journalCode=rftg20|journal = Fatigue: Biomedicine, Health & Behavior |volume=4|issue=3 | pages = 132-145|doi=10.1080/21641846.2016.1207400|quote=|via=}}</ref> - [http://www.tandfonline.com/doi/abs/10.1080/21641846.2016.1207400?journalCode=rftg20 (Abstract)] *2016, Support for the [[Microgenderome]]: Associations in a Human Clinical Population<ref name="Wallis2016" /> - [http://www.nature.com/articles/srep19171 (Full Text)] *2017, Examining clinical similarities between myalgic encephalomyelitis/chronic fatigue syndrome and d-lactic acidosis: a systematic review<ref name="Wallis2017" /> - [https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-017-1229-1 (Full Text)] *2017, The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome<ref name="Armstrong, 2017" /> *2017, Activin B is a novel [[Diagnostic biomarker|biomarker]] for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) diagnosis: a cross sectional study<ref>{{Citation | last1 = Lidbury | first1 = Brett | authorlink = Brett Lidbury | last2 = Badia | first2 = Kita | authorlink2 = | last3 = Lewis | first3 = Donald | authorlink3 = Donald Lewis | last4 = Hayward | first4 = Susan | authorlink4 = | last5 = Ludlow | first5 = Helen | authorlink5 = | last6 = Hedger | first6 = Mark | author-link6 = | last7 = de Kretser | first7 = David | author-link8 = | title = Activin B is a novel biomarker for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) diagnosis: a cross sectional study|journal = Journal of Translational Medicine|volume=|issue=| page = | date = 2017 | pmid= |doi=10.1186/s12967-017-1161-4}}</ref> - [https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-017-1161-4 (Full text)] *2018, Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection<ref name="Richardson, 2018" /> *2018, Open-label pilot for treatment targeting gut dysbiosis in myalgic encephalomyelitis/chronic fatigue syndrome: neuropsychological symptoms and sex comparisons<ref>{{Cite journal | last = Wallis | first = Amy | authorlink = Amy Wallis | last2 = Ball | first2 = Michelle | authorlink2 = Michelle Ball | last3 = Butt | first3 = Henry L | authorlink3 = Henry Butt | last4 = Lewis | first4 = Donald P | authorlink4 = Donald Lewis | last5 = McKechnie | first5 = Sandra | last6 = Paull | first6 = Phillip | last7 = Jaa-Kwee | first7 = Amber | last8 = Bruck|first8 = Dorothy | author-link8 = Dorothy Bruck | title = Open-label pilot for treatment targeting gut dysbiosis in myalgic encephalomyelitis/chronic fatigue syndrome: neuropsychological symptoms and sex comparisons|journal=Journal of Translational Medicine|volume = 16|issue=1 | page = 24 | date = 2018|doi=10.1186/s12967-018-1392-z}}</ref> - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801817/ (Full Text)] [https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-018-1413-y (Correction)] *2019, Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases<ref>{{Cite journal | last = McGregor | first = Neil R. | authorlink = Neil McGregor | last2 = Armstrong | first2 = Christopher W. | authorlink2 = Christopher Armstrong | last3 = Lewis | first3 = Donald P. | authorlink3 = Donald Lewis | last4 = Gooley | first4 = Paul R. | authorlink4 = Paul Gooley | authorlink5 = | author-link6 = | date = 2019-07-04 | title = Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases |url =https://www.mdpi.com/2075-4418/9/3/70|journal=Diagnostics|language=en|volume=9|issue=3 | pages = 70|doi=10.3390/diagnostics9030070|issn=2075-4418|quote=|via=}}</ref> - [https://www.mdpi.com/2075-4418/9/3/70/htm (Full text)] *2019, An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients<ref>{{Cite journal | last = Missailidis | first = Daniel | authorlink = | last2 = Annesley | first2 = Sarah | authorlink2 = | last3 = Allan | first3 = Claire | authorlink3 = | last4 = Sanislav | first4 = Oana | authorlink4 = | last5 = Lidbury | first5 = Brett | authorlink5 = Brett Lidbury | last6 = Lewis | first6 = Don | author-link6 = Donald Lewis | last7 = Fisher | first7 = Paul | author-link8 = Paul Fisher | date = 2019-09-04 | title = An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients |url =http://www.preprints.org/manuscript/201909.0043/v1|journal=Preprints|volume=|issue= | pages = |doi=10.20944/preprints201909.0043.v1|pmc=|pmid=|access-date=|quote=|via=}}</ref> - [https://www.preprints.org/manuscript/201909.0043/v1 (Abstract)] ==Clinic location== Dr Lewis founded the CFS Discovery clinic in Donvale, Melbourne, which has since closed. ==Talks and interviews== * 2011 - Dr Don Lewis: Latest Understanding of ME/CFS (video)<ref name="Lewis2011Emerge" /> * 01 Jun 2018 - Radio Interview - ABC Radio National (Australia) - Evenings with Christine Anu - [http://www.abc.net.au/radio/programs/nationalevenings/evenings/9802314 What do we know about Chronic Fatigue Syndrome]<ref>{{citation | last =Lewis | first = Donald P | authorlink = Donald Lewis | last2 = Guthridge | first2 = Mark | author-link2 = Mark Guthridge | title = What Do We Know About Chronic Fatigue Syndrome?|journal=ABC Radio National (Australia) - Evenings with Christine Anu | date = Jun 1, 2018 | url = http://www.abc.net.au/radio/programs/nationalevenings/evenings/9802314}}</ref> with Dr Donald Lewis & Dr [[Mark Guthridge]] (from timestamp 1:34:40 to 1:54:45) * 19 Aug 2019 - [http://www.virology.ws/2019/08/19/trial-by-error-my-interview-with-melbournes-dr-don-lewis/ Trial By Error: My Interview with Melbourne’s Dr Don Lewis] == See also == ==Learn more== ==References== <references> <ref name="Sheedy2009">{{citation | last1 = Sheedy | first1 = John R | author-link1 = | last2 = Wettenhall | first2 = Richard EH | authorlink2 = | last3 = Scanlon | first3 = Denis | authorlink3 = | last4 = Gooley | first4 = Paul R | authorlink4 = Paul Gooley | last5 = Lewis | first5 = Donald P | authorlink5 = Donald Lewis | last6 = McGregor | first6 = Neil | author-link6 = Neil McGregor | last7 = Stapleton | first7 = David I | author-link8 = David Stapleton | last8 = Butt | first8 = Henry L | author-link8 = Henry Butt | last9 = De Meirleir | first9 = Kenny L | author-link9 = Kenny de Meirleir | title = Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome | journal =In Vivo | volume = 23 | issue = 4 | page = 621-8 | date =Jul 2009 | pmid = 19567398 | url = http://iv.iiarjournals.org/content/23/4/621.long }}</ref> <ref name="Lewis2011Emerge">{{citation | last1 = Lewis | first1 = Donald P | author-link1 = Donald Lewis | title = Dr Don Lewis: Latest Understanding of ME/CFS (video) | journal =Emerge Australia Seminar | location = Melbourne | date = May 2011 | url = https://vimeo.com/107656181 }}</ref> <ref name="Reynolds2014">{{citation | last1 = Reynolds | first1 = GK | author-link1 = | last2 = Lewis | first2 = Donald P | authorlink2 = Donald Lewis | last3 = Richardson | first3 = AM | authorlink3 = | last4 = Lidbury | first4 = Brett A | authorlink4 = Brett Lidbury | title = Comorbidity of postural orthostatic tachycardia syndrome and chronic fatigue syndrome in an Australian cohort | journal =Journal of Internal Medicine | volume = 275 | issue = 4 | pages = 409–417 | date =April 2014 | pmid = 24206536 | doi = 10.1111/joim.12161 | url = http://onlinelibrary.wiley.com/doi/10.1111/joim.12161/abstract }}</ref> <ref name="Armstrong, 2015">{{Citation | last1 = Armstrong | first1 = Christopher W. | author-link1 = Christopher Armstrong | last2 = McGregor | first2 = Neil R. | authorlink2 = Neil McGregor | last3 = Lewis | first3 = Donald P. | authorlink3 = Donald Lewis | last4 = Butt | first4 = Henry L. | authorlink4 = Henry Butt | last5 = Gooley | first5 = Paul R. | authorlink5 = Paul Gooley | title = Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients | journal =Metabolomics | volume = 11 | issue = 6 | page = 1626–1639 | date = 2015 | doi = 10.1007/s11306-015-0816-5 }}</ref> <ref name="Jackson2015">{{citation | last1 = Jackson | first1 = Melinda L | author-link1 = Melinda Jackson | last2 = Butt | first2 = Henry L | authorlink2 = Henry Butt | last3 = Ball | first3 = Michelle | authorlink3 = Michelle Ball | last4 = Lewis | first4 = Donald P | authorlink4 = Donald Lewis | last5 = Bruck | first5 = Dorothy | authorlink5 = Dorothy Bruck | title = Sleep quality and the treatment of intestinal microbiota imbalance in Chronic Fatigue Syndrome: A pilot study | journal =Sleep Science | volume = 8 | issue = 3 | page = 124-33 | date = 23 Oct 2015 | pmid = 26779319 | doi = 10.1016/j.slsci.2015.10.001 | url = http://www.sciencedirect.com/science/article/pii/S1984006315000632 }}</ref> <ref name="Richardson, 2018">{{Citation | last1 = Richardson | first1 = Alice| author-link1 = | last2 = Lewis | first2 = Donald | authorlink2 = Donald Lewis | last3 = Kita | first3 = Badia| authorlink3 = | last4 = Ludlow | first4 = Helen | authorlink4 = | last5 = Groome | first5 = Nigel | authorlink5 = | last6 = Hedger | first6 = Mark | author-link6 = | last7 = de Kretser | first7 = David | author-link7 = | last8 = Lidbury | first8 = Brett| author-link8 = Brett Lidbury | title = Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection | journal =Journal of Translational Medicine | volume = 16 | issue = | page = 97 | date = 2018 | pmid = | doi = 10.1186/s12967-018-1473-z }}</ref> <ref name="Wallis2016">{{citation | last1 = Wallis | first1 = Amy | author-link1 = Amy Wallis | last2 = Butt | first2 = Henry L | authorlink2 = Henry Butt | last3 = Ball | first3 = Michelle | authorlink3 = Michelle Ball | last4 = Lewis | first4 = Donald P | authorlink4 = Donald Lewis | last5 = Bruck | first5 = Dorothy | authorlink5 = Dorothy Bruck | title = Support for the Microgenderome: Associations in a Human Clinical Population | journal =Scientific Reports | volume = 6| pages = 19171 | date = 13 Jan 2016 | pmid = 26757840 | doi = 10.1038/srep19171 | url = http://www.nature.com/articles/srep19171 }}</ref> <ref name="Wallis, book, 2017">{{citation | last1 = Wallis | first1 = Amy | author-link1 = Amy Wallis | last2 = Jackson | first2 = Melinda L | authorlink2 = Melinda Jackson | last3 = Ball | first3 = Michelle | authorlink3 = Michelle Ball | last4 = Lewis | first4 = Donald | authorlink4 = Donald Lewis | last5 = Bruck | first5 = Dorothy | authorlink5 = Dorothy Bruck | title = Sleep, Cognitive and Mood Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, in ''The Handbook of Stress and Health: A Guide to Research and Practice'' | date = 2017 | doi = 10.1002/9781118993811.ch31 }}</ref> <ref name="Wallis2017">{{citation | last1 = Wallis | first1 = Amy | author-link1 = Amy Wallis | last2 = Ball | first2 = Michelle | authorlink2 = Michelle Ball | last3 = McKechnie | first3 = Sandra | authorlink3 = | last4 = Butt | first4 = Henry L | authorlink4 = Henry Butt | last5 = Lewis | first5 = Donald P | authorlink5 = Donald Lewis | last6 = Bruck | first6 = Dorothy | author-link6 = Dorothy Bruck | title = Examining clinical similarities between myalgic encephalomyelitis/chronic fatigue syndrome and d-lactic acidosis: a systematic review | journal =Journal of Translational Medicine | volume = | issue = 15 | page = 129 | date = 2017 | doi = 10.1186/s12967-017-1229-1 }}</ref> <ref name="Armstrong, 2017">{{Citation | last1 = Armstrong | first1 = Christopher W. | author-link1 = Christopher Armstrong | last2 = McGregor | first2 = Neil R. | authorlink2 = Neil McGregor | last3 = Lewis | first3 = Donald P. | authorlink3 = Donald Lewis | last4 = Butt | first4 = Henry L. | authorlink4 = Henry Butt | last5 = Gooley | first5 = Paul R. | authorlink5 = Paul Gooley | title = The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome | journal =Metabolomics | volume = 13 | issue = 1 | page = | date = 2017 | doi = 10.1007/s11306-016-1145-z }}</ref> </references> [[Category:Researchers]] [[Category:Australia researchers]] [[Category:Clinicians]] [[Category:Australian clinicians]]
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