Cytomegalovirus: Difference between revisions

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'''Cytomegalovirus''' (CMV) is a common [[herpesvirus]] found in humans.  Like other herpesviruses, it is a life-long infection that remains in a latent state inside the human body, until it is 'reactivated' by appropriate conditions. CMV infects between 60% to 70% of adults in industrialized countries and close to 100% in emerging countries.  Much is unknown about this virus, although it has been found in salivary glands and myeloid blood cells such as [[monocyte]]s.  It has also been linked to the development of certain cancers.  Congenital CMV is a leading infectious cause of deafness, learning disabilities, and intellectual disability.  A common treatment for CMV is [[valganciclovir]], commonly known as Valcyte.<ref>{{Cite book|last=Gupta|first=Mohit|last2=Shorman|first2=Mahmoud|date=2019|title=Cytomegalovirus|url=http://www.ncbi.nlm.nih.gov/books/NBK459185/|location=Treasure Island (FL)|publisher=StatPearls Publishing|pmid=29083720}}</ref> 
'''Cytomegalovirus''' (CMV) is a common [[herpesvirus]] found in humans.  Like other herpesviruses, it is a life-long infection that remains in a latent state inside the human body, until it is 'reactivated' by appropriate conditions.  


Several herpesviruses including cytomegalovirus may cause false positives on [[Lyme disease]] tests.<ref name="Goossens" />
==Prevalence ==
CMV infects between 60% to 70% of adults in industrialized countries and close to 100% in emerging countries.{{citation needed|date=2022}} 
 
Much is unknown about CMV, although it has been found in salivary glands and myeloid blood cells such as [[monocyte]]s.  It has also been linked to the development of certain cancers.  Congenital CMV is a leading infectious cause of deafness, learning disabilities, and intellectual disability.  A common treatment for CMV is [[valganciclovir]], commonly known as Valcyte.<ref name="Gupta2019">{{Cite book|last=Gupta|first=Mohit|last2=Shorman|first2=Mahmoud|date=2019|title=Cytomegalovirus|url=http://www.ncbi.nlm.nih.gov/books/NBK459185/|location=Treasure Island (FL)|publisher=StatPearls Publishing|pmid=29083720}}</ref> 
 
Several herpesviruses including cytomegalovirus may cause false positives on [[Lyme disease]] tests.<ref name="Goossens1999a">[https://link.springer.com/article/10.1007/BF02561539 Goossens, H. A. T., A. E. J. M. van den Bogaard, and M. K. E. Nohlmans. Epstein-Barr virus and cytomegalovirus infections cause false-positive results in IgM two-test protocol for early Lyme borreliosis. Infection 27, no. 3 (1999): 231-231.]</ref><ref name="Goossens1999b">https://link.springer.com/article/10.1007/s100960050347</ref><ref name="Dessau2018">https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(17)30488-3/abstract</ref>


==Treatments ==
==Treatments ==
*[[Artesunate]]
*[[Artesunate]]
*[[Gancyclovir|Ganciclovir]] (brand names include Cytovene)
*[[Gancyclovir]] (brand names include Cytovene)
*[[Valganciclovir]] (brand names include Valcyte)
*[[Valganciclovir]] (brand names include Valcyte)


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* [[List of herpesvirus infection studies]]
* [[List of herpesvirus infection studies]]


== References ==
== Learn more ==
<references>
==References==
{{Reflist}}
<ref name="Goossens">Goossens HA, Nohlmans MK, van den Bogaard AE. Epstein-Barr virus and cytomegalovirus infections cause false-positive results in IgM two-test protocol for early Lyme borreliosis. Infection 1999;27:231.</ref>
<ref name="Goossens">Goossens HA, Nohlmans MK, van den Bogaard AE. Epstein-Barr virus and cytomegalovirus infections cause false-positive results in IgM two-test protocol for early Lyme borreliosis. Infection 1999;27:231.</ref>
</references>


[[Category:Infectious agents]]
[[Category:Infectious agents]]
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[[Category:Virology]]
[[Category:Virology]]
[[Category:Viruses]]
[[Category:Viruses]]
[[Category:Herpesviruses]]

Revision as of 20:15, August 4, 2022

Cytomegalovirus (CMV) is a common herpesvirus found in humans. Like other herpesviruses, it is a life-long infection that remains in a latent state inside the human body, until it is 'reactivated' by appropriate conditions.

Prevalence[edit | edit source]

CMV infects between 60% to 70% of adults in industrialized countries and close to 100% in emerging countries.[citation needed]

Much is unknown about CMV, although it has been found in salivary glands and myeloid blood cells such as monocytes. It has also been linked to the development of certain cancers. Congenital CMV is a leading infectious cause of deafness, learning disabilities, and intellectual disability. A common treatment for CMV is valganciclovir, commonly known as Valcyte.[1]

Several herpesviruses including cytomegalovirus may cause false positives on Lyme disease tests.[2][3][4]

Treatments[edit | edit source]

Notable studies[edit | edit source]

  • 2020, Cytomegalovirus, Epstein-Barr Virus, and Human herpesvirus-6 Infections in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome[5] - (Abstract)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

[1]

  1. Goossens HA, Nohlmans MK, van den Bogaard AE. Epstein-Barr virus and cytomegalovirus infections cause false-positive results in IgM two-test protocol for early Lyme borreliosis. Infection 1999;27:231.