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Cryotherapy
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=== Immune system === Cryotherapy may improve response to experimental endotoxin exposure. Hypothermic rabbits have a ten times greater resistance to bacterial endotoxins than normal rabbits.<ref>{{Cite journal | last = Liu|first = R.K. | date = 1972 | title = The Effect of Lowered Body Temperature on Lifespan and Immune and Non-Immune Processes |url =https://www.karger.com/Article/Abstract/211944|journal=Gertontology|volume=18 | pages = 363β388|via=}}</ref><ref>{{Cite journal | last = Rikke | first = Brad | date = 2004 | title = Lower body temperature as a potential mechanism of life extension in homeotherms |url =https://www.sciencedirect.com/science/article/pii/S0531556504001172|journal=Experimental Gerontology|volume=39 | pages = 1431|via=}}</ref> One study in humans attempted to test the effects of [[Wim Hof]]'s "method" β a combination of mediation, breathing techniques and immersion in cold water to activate the [[sympathetic nervous system]] β in a group of healthy volunteers. As compared to the control group, the treatment group had improved immune response when exposed to [[Escherichia coli|e-coli'']].<ref name="Kox2014">{{Cite journal | last = Kox | first = Matthijs| date = 2014 | title = Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans |url =http://www.pnas.org/content/111/20/7379.full|journal=Proceedings of the National academy of Sciences|volume=111|issue =20 | pages = 7379-7384|via=}}</ref>
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