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Co-conditioning theory
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{{stub}} The co-conditioning theory of [[ME/CFS]] was first proposed in 2010 and is [[Biopsychosocial model|biopsychosocial-based theory]].<ref name=":0">{{Cite journal | last = Tanaka | first = Masaaki | authorlink = Masaaki Tanaka | last2 = Watanabe | first2 = Yasuyoshi | author-link2 = Yasuyoshi Watanabe | date = Aug 2010 | title = A new hypothesis of chronic fatigue syndrome: Co-conditioning theory | url = https://doi.org/10.1016/j.mehy.2010.02.032 | journal = Medical Hypotheses | volume = 75 | issue = 2 | pages = 244–249|doi=10.1016/j.mehy.2010.02.032|issn=0306-9877|quote=|via=}}</ref> Co-conditioning is proposed to cause [[chronic fatigue syndrome]] as follows: "after repetitive overwork and/or stress, alarm signal to rest and fatigue sensation may cause in response to an unconditioned stimulus (impaired [[homeostasis]] and function) that has been paired with a conditioned stimulus (overwork and/or stress)".<ref name=":0" /> ==Theory== ==Evidence== ==Treatment== A re-co-conditioning treatment is proposed, including cognitive behavioral therapy for "stress, stress responses, overwork, inactivity, and the psychological responses as a result of the familial, social, economic, and educational handicaps" combined with medication to reduce symptoms and restore homeostasis.<ref name=":0" /> ==See also== * [[:Category:Medical hypotheses|Medical hypotheses]] (category) ==Learn more== * * [https://www.sciencedirect.com/science/article/pii/S030698771000108 A new hypothesis of chronic fatigue syndrome: Co-conditioning theory]<ref name=":0" /> ==References== {{Reflist}} [[Category:Medical hypotheses]]
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