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Buspirone challenge test
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====== Cleare et al 1995 ====== The [[Anthony Cleare|Cleare]] 1995 study<ref>{{Cite journal | last = Cleare | first = A.J. | last2 = Bearn | first2 = J. | last3 = Allain | first3 = T. | last4 = McGregor | first4 = A. | last5 = Wessely | first5 = S. | last6 = Murray | first6 = R.M. | last7 = O'Keane | first7 = V. | date = 1995-08-18 | title = Contrasting neuroendocrine responses in depression and chronic fatigue syndrome | url =https://www.ncbi.nlm.nih.gov/pubmed/8550954 | journal = Journal of Affective Disorders | volume = 34 | issue = 4 | pages = 283–289|issn=0165-0327|pmid=8550954}}</ref> found the selective serotonin-releasing agent d-fenfluramine elicited a high degree of prolactin release in ME/CFS patients, an intermediate degree of release in healthy controls, and a low degree of release in depressed patients. The prolactin response to d-fenfluramine appears to be mediated by indirect activation of 5-HT2 receptors without 5-HT1A receptors playing a significant role.<ref name=":2" />
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