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Bupropion
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'''Bupropion''' is an atypical [[antidepressant]] medication sold under the brand names include '''Wellbutrin''', '''Aplenzin''', and '''Zyban''', and formerly Budeprion.<ref name="medline">{{Cite web | url = https://medlineplus.gov/druginfo/meds/a695033.html | title = Bupropion: MedlinePlus Drug Information | website = medlineplus.gov|language=en | access-date = 2019-01-08}}</ref><ref name="PMC2729622" /><ref name="patch" /> In addition to treating [[depression]] and severe pain, it is also used to treat [[seasonal affective disorder]] (SAD), and to reduce cravings in smoking cessation and drug addiction.<ref name="medline" /><ref name="drugscom" /> ==Types== Bupropion is available in different forms, and may be combined with other drugs for particular uses, including * Bupropion for smoking cessation, brand name '''Zyban''' * Bupropion for major [[depression]], brand name '''Wellbutrin'''<ref name="drugscom">https://www.drugs.com/bupropion</ref> ==Theory == Buproprion, like all antidepressants, does not address the underlying mechanisms of ME/CFS, so should not be regarded as a cure. It should be used only to reduce particular symptoms or treat a co-existing disorder (e.g. depression), and it is not a primary treatment for ME/CFS.<ref name="canadianconsensus-CCC">{{Citation | last1 = Carruthers | first1 = Bruce M. | author-link1 = Bruce Carruthers | last2 = Jain | first2 = Anil Kumar | author-link2 = Anil Kumar Jain | last3 = De Meirleir | first3 = Kenny L. | author-link3 = Kenny De Meirleir | last4 = Peterson | first4 = Daniel L. | author-link4 = Daniel Peterson | last5 = Klimas | first5 = Nancy G. | author-link5 = Nancy Klimas | last6 = Lerner | first6 = A. Martin | author-link6 = Martin Lerner | last7 = Bested | first7 = Alison C. | author-link8 = Alison Bested | last8 = Flor-Henry | first8 = Pierre | author-link8 = Pierre Flor-Henry | last9 = Joshi | first9 = Pradip | author-link9 = Pradip Joshi | last10 = Powles | first10 = AC Peter | author-link10 = A C Peter Powles | last11 = Sherkey | first11 = Jeffrey A. | author-link11 = Jeffrey Sherkey | last12 = van de Sande | first12 = Marjorie I. | author-link12 = Marjorie van de Sande | title = Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Clinical Working Case Definition, Diagnostic and Treatment Protocols| journal = Journal of Chronic Fatigue Syndrome | volume = 11 | issue = 2 | pages = 7-115 | date = 2003 | pmid = | doi = 10.1300/J092v11n01_02| url = http://www.investinme.org/Documents/PDFdocuments/CanadianDefinitionME-CFS.pdf}}</ref> ME/CFS patients may tolerate brand name bupropion better than generic versions due to sensitivities.{{Citation needed}} ==Evidence == ==Clinicians== ==Risks and safety== ==Costs and availability== ==Learn more == *[https://www.drugs.com/bupropion Bupropion] for depression and psychiatric use - Drugs.com *[https://medlineplus.gov/druginfo/meds/a613042.html Bupropion transdermal for pain] - Medline Plus ==See also == *[[Antidepressant]] == References == {{Reflist}} [[Category:Antidepressants]] [[Category:Norepinephrine-dopamine reuptake inhibitors]]
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