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Bromelain
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{{stub}} '''Bromelain''' is an enzyme that naturally occurs in '''pineapple''' extract. Bromelain supplements are often used for inflammation and pain, especially from osteoarthritis, to debride burns or other wounds (as '''Debridase'''), to increase absorption of [[Antibiotic|antibiotics]] or other medications, and for sinitus or bronchitis.<ref name="webmd">{{Cite web |access-date = 2021-03-04 | website = WebMD| title = Bromelain |url = https://www.webmd.com/diet/supplement-guide-bromelain-bromelin}}</ref><ref name="drugscom">{{Cite web |access-date = 2021-03-04 | website = drugs.com| title = Pineapple|url = https://www.drugs.com/npp/pineapple.html}}</ref><ref name="Pavan2012">{{Cite journal | last = Pavan | first = Rajendra | last2 = Jain | first2 = Sapna | last3 = Shraddha | last4 = Kumar | first4 = Ajay | date = 2012 | title = Properties and Therapeutic Application of Bromelain: A Review | url =https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529416/ | journal = Biotechnology Research International | volume = |doi=10.1155/2012/976203|issn=2090-3138|pmc=3529416|pmid=23304525}}</ref> Bromelain supplements usually contain '''stem bromelain''' rather than fruit bromelain from the pineapple fruit.<ref name="Pavan2012" /> ==Theory == ==ME/CFS == ==Evidence == Bromelain has been found to help modulate the immune system.<ref name="Pavan2012" /> ==Costs and availability == Bromelain is an inexpensive supplement that can be bought over the counter.<ref name="drugscom" /> Bromelain is sometimes combined with trypsin/rutin (as Phlogenzym).<ref name="Pavan2012" /> ==Risks and safety == ==See also == *[[Nonsteroidal anti-inflammatory drug|Nonsteroid anti-inflammatory drug]] *[[Pain]] *[[Chronic pain]] ==Learn more == *[https://www.webmd.com/diet/supplement-guide-bromelain-bromelin Bromelain] - WebMD *[https://www.drugs.com/npp/pineapple.html Pineapple] - drugs.com ==References == {{Reflist}} [[Category:Potential treatments]] [[Category:Anti-inflammatories]] [[Category:Analgesics]] [[Category:Supplements]] [[Category:Immunomodulators]]
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