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==Notable studies related to ME/CFS== *2017, Neural Consequences of Post-Exertion Malaise in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome<ref name="Cook, 2017">{{Cite journal | last1 = Cook | first1 = Dane B. | author-link1 = Dane Cook | last2 = Light | first2 = Alan R. | author-link2 = Alan Light | last3 = Light | first3 = Kathleen C. | author-link3 = Kathleen Light | last4 = Broderick | first4 = Gordon | author-link4 = Gordon Broderick | last5 = Shields | first5 = Morgan R. | author-link5 = | last6 = Dougherty | first6 = Ryan J. | author-link6 = | last7 = Meyer | first7 = Jacob D. | author-link7 = | last8 = VanRiper | first8 = Stephanie | author-link8 = | last9 = Stegner | first9 = Aaron J. | author-link9 = | last10= Ellingson | first10 = Laura D. | author-link10 =| last11= Vernon | first11 = Suzanne D. | author-link11 = Suzanne Vernon | title = Neural Consequences of Post-Exertion Malaise in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome| journal = Brain, Behavior, and Immunity | volume = 62 | issue = | page = 87-99 | url = https://www.sciencedirect.com/science/article/pii/S088915911730051X | pmid = 28216087 | date = 2017 | doi = 10.1016/j.bbi.2017.02.009}}</ref> [http://www.sciencedirect.com/science/article/pii/S088915911730051X (Full Text)] *2017, Symptom variability following acute exercise in myalgic encephalomyelitis/chronic fatigue syndrome: a perspective on measuring post-exertion malaise<ref name="Lindheimer, 2017">{{Cite journal | last1 = Lindheimer | first1 = Jacob B. | author-link1 = | last2 = Meyer | first2 = Jacob D. | author-link2 = | last3 = Stegner | first3 = Aaron J. | author-link3 = | last4 = Dougherty | first4 = Ryan J. | author-link4 = | last5 = Van Riper | first5 = Stephanie M. | author-link5 = | last6 = Shields | first6 = Morgan | author-link6 = | last7 = Reisner | first7 = Amanda | author-link7 = | last8 = Shukla | first8 = Sanjay K. | author-link8 = | last9 = Light | first9 = Alan R. | author-link9 = Alan Light | last10= Yale | first10 = Steven | author-link10 = | last11= Cook | first11 = Dane B. | author-link11 = Dane Cook| title = Symptom variability following acute exercise in myalgic encephalomyelitis/chronic fatigue syndrome: a perspective on measuring post-exertion malaise| journal = Fatigue: Biomedicine, Health & Behavior | volume = 5 | issue = 2 | page = 69-88| date = 2017| url = https://doi.org/10.1080%2F21641846.2017.1321166 | pmid= | doi = 10.1080/21641846.2017.1321166}}</ref> [https://doi.org/10.1080/21641846.2017.1321166 (Abstract)] *2016, Gene expression factor analysis to differentiate pathways linked to fibromyalgia, chronic fatigue syndrome, and depression in a diverse patient sample<ref name="Iacob, 2016">{{Cite journal | last1 = Iacob | first1 = E | author-link1 = | last2 = Light | first2 = AR | author-link2 = Alan Light | last3 = Donaldson | first3 = GW | author-link3 =| last4 = Okifuji | first4 = A | author-link4 = | last5 = Hughen | first5 = RW | author-link5 = | last6 = White | first6 = AT | author-link6 = | last7 = Light | first7 = K | author-link8 = Kathleen Light| title = Gene expression factor analysis to differentiate pathways linked to fibromyalgia, chronic fatigue syndrome, and depression in a diverse patient sample| journal = Arthritis Care and Research | volume = 68 | issue = 1 | page = 132-40 | url = https://onlinelibrary.wiley.com/doi/epdf/10.1002/acr.22639 | pmc = PMC4684820 | date = 2016 | pmid = 26097208 | doi = 10.1002/acr.22639}}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684820/ (Full Text)] *2013, Post-Exertion Malaise in Chronic Fatigue Syndrome: Symptoms and Gene Expression<ref name="Meyer, 2013">{{Cite journal | last1 = Meyer | first1 = Jacob D | author-link1 = | last2 = Light | first2 = Alan R | author-link2 = Alan Light | last3 = Shukla | first3 = Sanjay K | author-link3 = | last4 = Clevidence | first4 = Derek | author-link4 = | last5 = Yale | first5 = Steven | author-link5 = | last6 = Stegner | first6 = Aaron J | author-link6 = | last7 = Cook | first7 = Dane C | author-link8 = Dane Cook| title = Post-Exertion Malaise in Chronic Fatigue Syndrome: Symptoms and Gene Expression| journal = Fatigue: Biomedicine, Health, & Behavior | volume = 1 | issue = 4 | page = 190-209 | date = 2013| url = https://www.tandfonline.com/doi/full/10.1080/21641846.2013.838444 |pmid= | doi = 10.1080/21641846.2013.838444}}</ref> [https://www.researchgate.net/profile/Jacob-Meyer-5/publication/258165434_Post-exertion_malaise_in_chronic_fatigue_syndrome_Symptoms_and_gene_expression/links/55269a910cf2f6e651697982/Post-exertion-malaise-in-chronic-fatigue-syndrome-Symptoms-and-gene-expression.pdf (Full text)] *2013, Differing [[leukocyte]] gene expression profiles associated with fatigue in patients with prostate cancer versus chronic fatigue syndrome<refname="Light2013Prostate">{{Cite journal | last1 = Light | first1 = K.C. | author-link = Kathleen Light | last2 = Agarwal | first2 = N. | last3 = Iacob | first3 = E. | last4 = White | first4 = A.T. | author-link4 = Andrea White | last5 = Kinney | first5 = A.Y. | last6 = Vanhaitsma | first6 = T.A. | last7 = Aizad | first7 = H. | last8 = Hughen | first8 = R.W. | last9 = Bateman | first9 = L. | author-link9 = Lucinda Bateman | last10 = Light | first10 = A.R. | date = 2013 | title = Differing leukocyte gene expression profiles associated with fatigue in patients with prostate cancer versus chronic fatigue syndrome | journal = Psychoneuroendocrinology | volume = 38 | issue = 12 | pages = 2983-2995 | doi = 10.1016/j.psyneuen.2013.08.008 | pmid = 24054763 | pmc = PMC3848711 | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848711 }}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848711/ (Full Text)] *2012, Genetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia with and without Comorbid Chronic Fatigue Syndrome<ref name="Light2012Stress">{{Cite journal | last1 = Light | first1 = KC | author-link = Kathleen Light | last2 = White | first2 = AT | author-link2 = Andrea White | last3 = Tadler | first3 =S | last4 = Iacob | first4 = E| last5 = Light | first5 = Alan R | author-link5 = Alan Light | url= https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200121/ | title = Genetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia with and without Comorbid Chronic Fatigue Syndrome | journal = Pain Research and Treatment | date = 2012 | page = 427869 | pmc = PMC3200121 |doi= 10.1155/2012/427869}}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200121/ (Full text)] *2012, Differences in metabolite-detecting, adrenergic, and immune gene expression after moderate exercise in patients with chronic fatigue syndrome, patients with [[multiple sclerosis]], and healthy controls<ref name="White, 2012">{{Cite journal | last1 = White | first1 = AT | author-link1 = Andrea White | last2 = Light | first2 = AR | author-link2 = Alan Light | last3 = Hughen | first3 = RW | author-link3 = | last4 = Vanhaitsma | first4 = TA | author-link4 = | last5 = Light | first5 = KC | author-link5 = Kathleen Light| title = Differences in metabolite-detecting, adrenergic, and immune gene expression after moderate exercise in patients with chronic fatigue syndrome, patients with multiple sclerosis, and healthy controls| journal = Psychosomatic Medicine | volume = 74 | issue = 1 | page = 46-54 | date = 2012| pmid= | pmc = PMC3256093| url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256093/| doi = 10.1097/PSY.0b013e31824152ed}}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256093/ (Full text)] *2012, Gene expression alterations at baseline and following moderate exercise in patients with Chronic Fatigue Syndrome and Fibromyalgia Syndrome<ref name="Light, 2012">{{Cite journal | last1 = Light | first1 = Alan R | author-link1 = Alan Light | last2 = Bateman | first2 = Lucinda | author-link2 = Lucinda Bateman | last3 = Jo | first3 = Daehyun | author-link3 = Daehyun Jo | last4 = Hughen | first4 = Ronald W | author-link4 = | last5 = Vanhaitsma | first5 = Timothy A | author-link5 = | last6 = White | first6 = AT | author-link6 = Andrea White | last7 = Light | first7 = Kathleen | author-link8 = Kathleen Light| title = Gene expression alterations at baseline and following moderate exercise in patients with Chronic Fatigue Syndrome and Fibromyalgia Syndrome| journal = Journal of Internal Medicine | volume = 271 | issue = 1 | page = 64-81 | date = 2012| pmid= | pmc = PMC3175315 | doi= 10.1111/j.1365-2796.2011.02405.x | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175315/ }}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3175315/ (Full Text)] *2011, Evidence for a heritable predisposition to Chronic Fatigue Syndrome<ref name="Albright, 2011">{{Cite journal | last1 = Albright | first1 = Frederick | author-link1 = | last2 = Light | first2 = Kathleen | author-link2 = Kathleen Light | last3 = Light | first3 = Alan | author-link3 = Alan Light | last4 = Bateman | first4 = Lucinda | author-link4 = Lucinda Bateman | last5 = Cannon-Albright | first5 = Lisa A | author-link5 = | title = Evidence for a heritable predisposition to Chronic Fatigue Syndrome| journal = BMC Neurology | volume = 11 | issue = | page = 62 | url = https://bmcneurol.biomedcentral.com/articles/10.1186/1471-2377-11-62 | pmc = PMC3128000 | pmid = 21619629 | date = 2011| doi= 10.1186/1471-2377-11-62}}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128000/ (Full Text)] *2011, Absence of XMRV retrovirus and other murine leukemia virus-related viruses in patients with chronic fatigue syndrome<ref name="Shin2011">{{Cite journal | last = Shin | first = Clifford H. | last2 = Bateman | first2 = Lucinda | author-link2 = Lucinda Bateman | last3 = Schlaberg | first3 = Robert | last4 = Bunker | first4 = Ashley M. | last5 = Leonard | first5 = Christopher J. | last6 = Hughen | first6 = Ronald W. | last7 = Light | first7 = Alan R. | author-link7 = Alan Light | last8 = Light | first8 = Kathleen C | author-link8 = Kathleen Light | last9 = Singh | first9 = Ila R. | date = Jul 2011 | title = Absence of XMRV retrovirus and other murine leukemia virus-related viruses in patients with chronic fatigue syndrome | url =https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126563/ | journal = Journal of Virology | volume = 85 | issue = 14 | pages = 7195-202|doi=10.1128/JVI.00693-11|via=}}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126563/ (Full Text)] *2010, A novel approach to studying the sensory pathways involved in the perception of fatigue<ref name="Pollak, 2010">{{Cite journal | last1 = Pollak | first1 = Kelly | author-link1 = | last2 = Jo | first2 = Daehyun | author-link2 = Daehyun Jo | last3 = Vanhaitsma | first3 = Timothy A | author-link3 = | last4 = Hughen | first4 = Ron W | author-link4 = | last5 = Light | first5 = Alan R | author-link5 = Alan Light| title = A novel approach to studying the sensory pathways involved in the perception of fatigue.| journal = Journal of Critical Care | volume = 25 | issue = 4 | page = e18 | date = 2010 | pmid = | doi = 10.1016/j.jcrc.2010.08.023 | url = https://www.jccjournal.org/article/S0883-9441(10)00264-9/abstract }}</ref> [https://www.jccjournal.org/article/S0883-9441(10)00264-9/abstract (Abstract)] *2010, Severity of symptom flare after moderate exercise is linked to cytokine activity in chronic fatigue syndrome<ref name="Light2010Flare">{{Cite journal | last1 = White | first1 = A.T. | author-link1 = Andrea White | last2 = Light | first2 = A.R. | author-link2 = Alan Light | last3 = Hughen | first3 = R.W. | author-link3 = | last4 = Bateman | first4 = L. | author-link4 = Lucinda Bateman | last5 = Martins | first5 = T.B. | author-link5 = | last6 = Hill | first6 = H.R. | author-link6 = | last7 = Light | first7 = K.C. | author-link8 = Kathleen Light | date = 2010 | title = Severity of symptom flare after moderate exercise is linked to cytokine activity in chronic fatigue syndrome | journal = Psychophysiology | volume = 47 | issue =4 | pages =615-24 |doi = 10.1111./j.1469-8986.2010.00978.x | pmc = PMC4378647 | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378647/ }}</ref> [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378647/ (Full Text)] *2009, Moderate Exercise Increases Expression for Sensory, Adrenergic, and Immune Genes in Chronic Fatigue Syndrome Patients But Not in Normal Subjects<ref name="Light2009">{{Cite journal | last1 = Light | first1 = A.R. | author-link = Alan Light | last2 = White | first2 = A.T. | author-link2 = Andrea White | last3 = Hughen | first3 =R.W. | last4 = Light | first4 = K.C. | author-link4 = Kathleen Light | date = 2009 | title = Moderate Exercise Increases Expression for Sensory, Adrenergic, and Immune Genes in Chronic Fatigue Syndrome Patients But Not in Normal Subjects | journal = The Journal of Pain | volume = 10 | pages = 1099-1112 | pmc = PMC2757484 | url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757484/}}</ref> [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757484/ (Full Text)]
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