ATP-Dependent RNA Helicase DDX51

ATP-Dependent RNA Helicase DDX51, or DEAD-Box Helicase 51 or DDX51 is a protein encoding gene and part of the DEAD-box helicases gene family. Alternative names for ATP-Dependent RNA Helicase DDX51 include DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 51, DEAD Box Protein 51, EC 3.6.4.13 and EC 3.6.1.

Notable studies

• May 24, 2019 - Genetic Predisposition for Immune System, Hormone, and Metabolic Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study (Full text)

See also

• ATP
• Metabolism
• ME/CFS Gene Study

Learn more

• DDX51 - Genecards

glutamate (Glu) - Glutamate is one of the amino acids used by the body to make proteins. It is a salt or ester of glutamic acid, and the terms glutamate and glutamic acid are often used interchangeably. It also functions as the principal excitatory neurotransmitter in the brain.

myalgic encephalomyelitis (M.E.) - A disease often marked by neurological symptoms, but fatigue is sometimes a symptom as well. Some diagnostic criteria distinguish it from chronic fatigue syndrome, while other diagnostic criteria consider it to be a synonym for chronic fatigue syndrome. A defining characteristic of ME is post-exertional malaise (PEM), or post-exertional neuroimmune exhaustion (PENE), which is a notable exacerbation of symptoms brought on by small exertions. PEM can last for days or weeks. Symptoms can include cognitive impairments, muscle pain (myalgia), trouble remaining upright (orthostatic intolerance), sleep abnormalities, and gastro-intestinal impairments, among others. An estimated 25% of those suffering from ME are housebound or bedbound. The World Health Organization (WHO) classifies ME as a neurological disease.