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1953 Maryland outbreak
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== Findings == * [[Lumbar puncture]]s were done on 25 of the cases and all 25 were negative for [[cerebrospinal fluid]] involvement. Eight lumbar punctures were repeated and all of those were negative, also.<ref name="McEvedy, 1970">{{Cite journal | last1 = McEvedy | first1 = Colin | author-link1 = Colin McEvedy | last2 = Beard | first2 = A.W. | author-link2 = William Beard | title = Concept of Benign Myalgic Encephalomyelitis | journal = [[British Medical Journal]] | volume = 1970 | issue = 1 | page = 11-15 | date = 1970 | pmid = 5411596 | url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1700895/}}</ref> * [[Paresis|Muscle weakness]] was confirmed in half of cases via quantitative muscular-testing procedures<ref name="Shelokov, 1957" /> * From several of the patients, the Bethesda-Ballerup paracolon organism was isolated. It was believed that this organism may have triggered the disease in the same manner as an infection of poliomyelitis virus precipitated other early epidemics.<ref name="Parish, 1978">{{Cite journal | last1 = Parish | first1 = J.G. | author-link1 = Gordon Parish| title = Early outbreaks of 'epidemic neuromyasthenia'| journal = Postgraduate Medical Journal | volume = 54 | issue = 637 | page = 711-717 | date = November 1978 | pmid = 370810| url = http://www.ncbi.nlm.nih.gov/pubmed/370810 }}</ref> * Hemoglobin determinations, erythrocyte counts, sedimentation rates and urinalyses were within normal limits * Tendency toward [[lymphocytosis]] in the acute phase * All [[infectious disease testing]] (including tests for a range of [[Enterovirus|enteroviruses]]) was negative
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