Luteinizing hormone subunit beta

Luteinizing hormone subunit beta or LHB or LSG-B refers to an enzyme or the gene encoded by the enzyme which may be associated with an increased risk of developing ME/CFS.

ME/CFS
The first publication from the long term ME/CFS Gene Study, which used the Fukuda criteria for chronic fatigue syndrome only, looked for the SNPs that were more common in CFS patients than in healthy people, and which were most likely to be harmful. LHB was one of the top ten genes most likely to be harmful that more common in CFS patients, occurring in over 70% of patients.

Notable studies

 * 2019, Genetic Predisposition for Immune System, Hormone, and Metabolic Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study (Full text)

Learn more

 * |title=LHB Gene - Gene card