Complexin 2

Complexin 2 or CPLX2 or CPX-2 or Synaphin 1 is a protein-encoding gene.

Function
CPLX2 is associated with a number of diseases including schizophrenia and familial temporal lobe 7 epilepsy.

ME/CFS
The ME/CFS Gene Study is still collecting data, but the pilot study publication by Perez et al. (2019) found that CPLX2 was one of the ten relatively common genes or gene variants that were both significantly more common in people with ME/CFS, and likely to be harmful.

Notable studies

 * 2019, Genetic Predisposition for Immune System, Hormone, and Metabolic Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study (Full text)

Learn more

 * CPLX2 Gene - Gene card