Immunoglobulin G

Immunoglobulin G or IgG is

Fibromyalgia
In 2021, Goebel et al. published research showing that fibromyalgia may be an immune system disease mediated by IgG; in an animal study on mice they found that the mice developed pain and cold intolerance symptoms consistent with fibromyalgia after receiving IgG from the blood of patients with fibromyalgia.

News and articles
"'Andersson and his colleagues harvested blood from 44 people with fibromyalgia and injected purified antibodies from each of them into different mice. The mice rapidly became more sensitive to pressure and cold, and displayed reduced grip strength in their paws. Animals injected with antibodies from healthy people were unaffected.'" Prof Camilla Svensson from the Karolinska Institute in Sweden, who was also involved in the study, said: "'Antibodies from people with fibromyalgia living in two different countries, the UK and Sweden, gave similar results, which adds enormous strength to our findings.'"

Notable studies

 * 2021, Passive transfer of fibromyalgia symptoms from patients to mice