Ozone

Ozone therapy or oxygen-ozone autohemotherapy or O2-O3-AHT is an oxidizing therapy which has been investigated as a potential treatment for ME/CFS and a number of other illnesses. Ozone or O3 is a unstable gas that is comprised of three oxygen atoms.

Notable studies

 * 2018, Oxygen-Ozone therapy is a potentially effective therapy in Chronic Fatigue Syndrome: Results of an Italian study in 65 patients - (Abstract)
 * 2022, Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Greatly Improved Fatigue Symptoms When Treated with Oxygen-Ozone Autohemotherapy - (Full text)

Food and Drug Administration

 * Apr 1, 2017, Sec. 801.415 Maximum acceptable level of ozone.