Roberto Patarca-Montero

Roberto Patarca-Montero, MD, PhD. Former Assistant Professor at University of Miami School of Medicine. Former editor of the Journal of Chronic Fatigue Syndrome. Researcher for AIDS and chronic fatigue syndrome.

Books

 * 2004, Medical Etiology, Assessment, and Treatment of Chronic Fatigue and Malaise: Clinical Differentiation and Intervention; What Does the Research Say?
 * 2004, Handbook of Cancer-Related Fatigue: What Does the Research Say?
 * 2003, Chronic Fatigue Syndrome, Genes, and Infection: The ETA-1/OP Paradigm — What Does the Literature Say?
 * 2002, Chronic Fatigue Syndrome and the Body's Immune Defense System: What Does the Research Say?
 * 2002, The Concise Encyclopedia of Fibromyalgia and Myofascial Pain
 * 2001, Treatment of Chronic Fatigue Syndrome in the Antiviral Revolution Era: What Does the Research Say?
 * 2001, Phytotherapy of Chronic Fatigue Syndrome: Evidence-Based and Potentially Useful Botanicals in the Treatment of CFS
 * 2000, Concise Encyclopedia of Chronic Fatigue Syndrome

Notable Studies

 * 2001, Cytokine and Other Immunologic Markers in Chronic Fatigue Syndrome and Their Relation to Neuropsychological Factors
 * 2000, Comparative Analysis of Lymphocytes in Lymph Nodes and Peripheral Blood of Patients with Chronic Fatigue Syndrome
 * 1995, Dysregulated Expression of Soluble Immune Mediator Receptors in a Subset of Patients with Chronic Fatigue Syndrome: Cross-Sectional Categorization of Patients by Immune Status - Abstract
 * 1994, Dysregulated expression of tumor necrosis factor in chronic fatigue syndrome: interrelations with cellular sources and patterns of soluble immune mediator expression"'ABSTRACT: Among a group of 70 individuals who met the criteria established by the Centers for Disease Control and Prevention (Atlanta) for chronic fatigue syndrome (CFS), 12%-28% had serum levels exceeding 95% of control values for tumor necrosis factor (TNF) alpha, TNF-beta, interleukin (IL) 1 alpha, IL-2, soluble IL-2 receptor (sIL-2R), or neopterin; overall, 60% of patients had elevated levels of one or more of the nine soluble immune mediators tested. Nevertheless, only the distributions for circulating levels of TNF-alpha and TNF-beta differed significantly in the two populations. In patients with CFS--but not in controls--serum levels of TNF-alpha, IL-1 alpha, IL-4, and sIL-2R correlated significantly with one another and (in the 10 cases analyzed) with relative amounts (as compared to beta-globin or beta-actin) of the only mRNAs detectable by reverse transcriptase-coupled polymerase chain reaction in peripheral-blood mononuclear cells: TNF-beta, unspliced and spliced; IL-1 beta, lymphocyte fraction; and IL-6 (in order of appearance). These findings point to polycellular activation and may be relevant to the etiology and nosology of CFS.'"