Talk:Pyridoxal-5'-phosphate

Suggestion for Discussion
Rename this page from "Pyridoxine" to "Pyridoxal-5'-Phosphate", abbreviated PLP.

The form of vitamin B6 that is found in meat is PLP, not Pyridoxine.

The form of vitamin B6 that is used by the body is PLP, not Pyridoxine.

Pyridoxine is a synthetic analogue of PLP that was designed to be more shelf-stable than the natural form of vitamin B6.

The synthetic form of Pyridoxine is now the preferred form in supplements precisely because it is shelf-stable.

Excessive, prolonged, use of the synthetic Pyridoxine causes neurological damage. No such damage is seen with the natural PLP.

Although it is sometimes suggested that "everyone can convert the synthetic form into the natural form", there is now some evidence that some neurological patients may lack the metabolic capacity to convert the synthetic form into the natural form, and therefore the distinction may be quite important.

For more information: https://lpi.oregonstate.edu/mic/vitamins/vitamin-B6

Tagging recent page editors for discussion: User:Notjusttired User:JohannaH User:Kmdenmark User:JenB

Pyrrhus (talk) 16:24, 12 February 2019 (EST)