CD1d

CD1d is a glycoprotein expressed on some cells containing antigens, such as in the case of intracellular infection. They activate natural killer cells.

The gamma herpesviruses Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus evade immune system detection and persist in B cells by down regulating the expression of CD1d, enabling them to avoid immune recognition by natural killer cells.