Lymphotoxin-alpha

Lymphotoxin-alpha or LTA or Tumor necrosis factor beta or TNF-beta gene encodes a cytokine that is produced by Th1 cells, CD8+ T cells, natural killer (NK) cells, B cells, and macrophages.

Alternative names for lymphotoxin-alpha include:
 * LT-Alpha
 * LT
 * Tumor Necrosis Factor Ligand Superfamily Member 1
 * TNFB
 * TNFSF1
 * Tumor Necrosis Factor Ligand 1E
 * TNF Superfamily, Member 1
 * TNLG1E

Function
The protein encoded by LTA is involved in many inflammatory, immunostimulatory, and antiviral responses.

LTA gene variants have been linked to susceptibility to leprosy type 4, myocardial infarction (heart attacks), non-Hodgkin's lymphoma, and psoriatic arthritis.

Learn more

 * LT-Alpha - Genecards