Central nervous system





The Central nervous system (CNS) basically includes the brain and the spinal cord.

Autopsy
ME/CFS patient autopsies have shown changes to the spinal cord.
 * Sophia Mirza's autopsy showed her spine contained massive infection.
 * Lynn Gilderdale had ganglionitis which is an infection of dorsal root ganglia of her spine, typical for a neurological illness.
 * Merryn Crofts's autopsy showed she had ganglionitis.

Brain imaging

 * Brains of People With Chronic Fatigue Syndrome Offer Clues About Disorder - New York Times: Well (2014)

Cytokines
Cytokines, found in spinal fluid, are increasingly found to be altered in ME/CFS patients and there are several studies by Ian Lipkin and Mady Hornig with the Microbe Discovery Project. See: Cytokine (Chronic Fatigue Syndrome section)

Neuropathological findings

 * 2017, CNS findings in chronic fatigue syndrome and a neuropathological case report