Julia Newton

Julia L. Newton is a Clinical Professor of Ageing and Medicine at the University of Newcastle in the United Kingdom. She has published a number of ME/CFS studies focusing on autonomic nervous system dysfunction and the role of inflammation in fatigue. She is a member of the UK CFS/ME Collaborative and is the Joint Medical Adviser of the charity Action for ME.

She is Director of the Newcastle Fatigue Research Group and Associate Medical Director for Research for Newcastle upon Tyne Hospitals NHS Foundation Trust.

Dr. Newton serves on the editorial board of the journal, Fatigue: Biomedicine, Health & Behavior, published on behalf of the IACFS/ME.

Notable studies

 * 2008, Postural orthostatic tachycardia syndrome is an under-recognized condition in chronic fatigue syndrome
 * 2009, Lower ambulatory blood pressure in chronic fatigue syndrome - (Abstract)
 * 2010, Impaired cardiovascular response to standing in Chronic Fatigue Syndrome - (Full Text)
 * 2010, The Newcastle NHS Chronic Fatigue Syndrome Service: not all fatigue is the same - (Full text)
 * 2011, Loss of capacity to recover from acidosis on repeat exercise in chronic fatigue syndrome: a case–control study - (Abstract)
 * 2012, Impaired cardiac function in chronic fatigue syndrome measured using magnetic resonance cardiac tagging - (Full Text)
 * 2012, Impaired blood pressure variability in chronic fatigue syndrome-a potential biomarker - (Abstract)
 * 2013, Cerebral vascular control is associated with skeletal muscle pH in chronic fatigue syndrome patients both at rest and during dynamic stimulation - (Full Text)
 * 2013, Contrasting chronic fatigue syndrome versus myalgic encephalomyelitis/chronic fatigue syndrome -(Abstract)
 * 2014, The role of sleep in chronic fatigue syndrome: a narrative review - (Abstract)
 * 2015, Autonomic function in chronic fatigue syndrome with and without painful temporomandibular disorder (Full text)
 * 2015, Chronic fatigue syndrome versus systemic exertion intolerance disease - (Abstract)
 * 2015, Factor Analysis of the DePaul Symptom Questionnaire: Identifying Core Domains - (Full Text)
 * 2015, Abnormalities of AMPK Activation and Glucose Uptake in Cultured Skeletal Muscle Cells from Individuals with Chronic Fatigue Syndrome - (Full Text)
 * 2015, Comparing and contrasting consensus versus empirical domains - (Abstract)
 * 2016, Understanding Muscle Dysfunction in Chronic Fatigue Syndrome
 * 2016, Treatment of insomnia reduces fatigue in chronic fatigue syndrome in those able to comply with the intervention - (Abstract)
 * 2016, Housebound versus nonhousebound patients with myalgic encephalomyelitis and chronic fatigue syndrome
 * 2016, Assessing current functioning as a measure of significant reduction in activity level
 * 2016, The Relationship between Age and Illness Duration in Chronic Fatigue Syndrome
 * 2016, Reduced cardiac volumes in chronic fatigue syndrome associate with plasma volume but not length of disease: a cohort study - (Full Text)
 * 2016, The aetiopathogenesis of fatigue: unpredictable, complex and persistent - (Full Text)
 * 2016, A comparative polysomnography analysis of sleep in healthy controls and patients with chronic fatigue syndrome
 * 2016, Case definitions integrating empiric and consensus perspectives - (Full Text)
 * 2016, Are Myalgic Encephalomyelitis and chronic fatigue syndrome different illnesses? A preliminary analysis - (Full Text)
 * 2017, Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia - (Full Text)
 * 2017, Are current chronic fatigue syndrome criteria diagnosing different disease phenotypes? - (Full Text)
 * 2017, Elevated brain natriuretic peptide levels in chronic fatigue syndrome associate with cardiac dysfunction: a case control study - (Full Text)
 * 2017, What is known about severe and very severe chronic fatigue syndrome? A scoping review - (Abstract)
 * 2017, Clinical criteria versus a possible research case definition in chronic fatigue syndrome/myalgic encephalomyelitis - (Full Text)
 * 2017, Two year follow-up of sleep diaries and polysomnography in chronic fatigue syndrome: a cohort study - (Abstract)
 * 2017, Energy envelope maintenance among patients with myalgic encephalomyelitis and chronic fatigue syndrome: Implications of limited energy reserves - (Abstract)
 * 2017, Cellular bioenergetics is impaired in patients with chronic fatigue syndrome - (Full Text)
 * 2017, Clinically proven mtDNA mutations are not common in those with chronic fatigue syndrome - (Full Text)
 * 2018, Liver volume is lower and associates with resting and dynamic blood pressure variability in chronic fatigue syndrome - (Abstract)
 * 2018, Metabolic abnormalities in chronic fatigue syndrome/myalgic encephalomyelitis: a mini-review - (Abstract)
 * 2018, Pharmacological activation of AMPK and glucose uptake in cultured human skeletal muscle cells from patients with ME/CFS - (Full Text)
 * 2018, Managing fatigue in postural tachycardia syndrome (PoTS): The Newcastle approach - (Abstract)
 * 2018, Rethinking childhood adversity in chronic fatigue syndrome - (Full Text)
 * 2018, Grey and white matter differences in Chronic Fatigue Syndrome – A voxel-based morphometry study - (Full Text)
 * 2018, Reduction of glucocorticoid receptor function in Chronic Fatigue Syndrome - (Full Text)
 * 2018, Defining the prevalence and symptom burden of those with self-reported severe chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME): a two-phase community pilot study in the North East of England - (Full Text)
 * 2019, MtDNA population variation in Myalgic encephalomyelitis/Chronic fatigue syndrome in two populations: A study of mildly deleterious variants - (Full text)
 * 2019, Impairments in cognitive performance in chronic fatigue syndrome are common, not related to co-morbid depression but do associate with autonomic dysfunction - (Full text)
 * 2019, Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study - (Full text)
 * 2019, Mitochondrial complex activity in permeabilised cells of chronic fatigue syndrome patients using two cell types - (Full text)
 * 2019, Conceptualizing the benefits of a group exercise program developed for those with chronic fatigue: a mixed methods clinical evaluation - (Abstract)
 * 2019, Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test (Full text)
 * 2020, The effect of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) severity on cellular bioenergetic function - (Full text)
 * 2020, Substrate utilisation of cultured skeletal muscle cells in patients with CFS - (Full text)
 * 2020, Prediction of Discontinuation of Structured Exercise Programme in Chronic Fatigue Syndrome Patient - (Full text)
 * 2021, Relationship between cardiopulmonary, mitochondrial and autonomic nervous system function improvement after an individualised activity programme upon Chronic Fatigue Syndrome patients - (Full text)

Talks and interviews

 * 2015, Standing up for Fatigue - Professor Julia Newton and Professor Jason Ellis at Gresham College (Video)
 * 2016, What is M E ? (Action for ME)

Talks for Dutch ME/CFS Society

2014, Playlist on YouTube containing:


 * 43. Introduction- experience with ME / Introductie - ervaring met ME - Prof. Dr. Julia Newton
 * 44. Neurocognitive problems in ME / Neuro-cognitieve problemen bij ME - Prof. Dr. Julia Newton
 * 45. ME and the bloodflow / ME en de bloedsomloop - Prof. Dr. Julia Newton
 * 46. The metabolism and the muscles / de spijsvertering en de spieren - Prof. Dr. Julia Newton
 * 47. ME and Sleep / ME en slaap- Prof. Dr. Julia Newton
 * 48. Ageing and ME/ Ouder worden en ME - Prof. Dr. Julia Newton
 * 49. ME and the future / ME en de toekonst - Prof. Dr. Julia Newton

Invest in ME International ME Conferences
 * 2008, Speaker at the 3rd Invest in ME International ME Conference on Autonomic Dysfunction: Identification of aetiologically distinct subject groups within ME/CFS - (Video)
 * 2014, Speaker at the 9th Invest in ME International ME Conference DVD available

Learn more

 * 2013, Taking Fatigue Seriously – An Interview with Dr. Julia Newton
 * 2013, Times 23 April 2013:Biological breakthrough offers fresh hope for ME sufferers (via the ME Association)
 * 2014, Daily Telegraph 17 June 2014: ME: one third of patients 'wrongly diagnosed
 * 2015, Inside the UK’s first ‘fatigue clinic’ (BBC Radio 5 Live, 7 December 2015)
 * 2016, What is ME? with Prof Julia Newton and Dr Gregor Purdie

Online presence

 * Newcastle University, Institute of Cellular Medicine: Julia Newton
 * Newcastle Fatigue Research Group
 * PubMed
 * Facebook
 * Email: julia.newton@ncl.ac.uk
 * Address: Clinical Academic Office, Level 6, Leazes Wing, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, United Kingdom