Glucocorticoid

Glucocorticoid is a corticosteroid, often simply referred to as a steroid.

ME/CFS
Studies published in 2017 and 2018 by de Vega et al. found dysregulated glucocorticoid receptor function in people with ME/CFS. While glucocorticoids are anti-inflammatory in the periphery, they can be inflammatory to the central nervous system; these findings suggest this effect may be amplified in people with ME/CFS due to increased sensitivity to glucocorticoids.

Studies

 * 2000, Decreased bone mineral density during low dose glucocorticoid administration in a randomized, placebo controlled trial. (Abstract)
 * 2017, Epigenetic modifications and glucocorticoid sensitivity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) (Full text)