Sirtuin 1

Sirtuin 1 or SIRT1 refers to an enzyme or the gene encoded by the enzyme from the silent information regulator (Sir2)-like family which may be associated with an increased risk of developing ME/CFS.

Other names
Sirtuin 1 is also known as
 * SIR2L1
 * NAD-Dependent Protein Deacetylase Sirtuin-1
 * NAD-Dependent Protein Deacylase Sirtuin-1
 * HSIRT1
 * HSIR2

Function
Sirtuins or silent information regulator (Sir2)-like family deacetylases are a group of enzymes found in the cytoplasm, mitochondria or nucleus of the cell and are ubiquitously expressed, and are closely related to histone deacetylases. Their purpose in human disease is not well understood.

Learn more

 * SIRT1 gene - Gene cards