Brain

Brain Facts
How does the brain operate? What happens when it is compromised, such as having a tumor or stroke? Does the presence of cognitive impairment represent compromise? What about dementia that is not Alzheimer's?

The National Institute of Neurological Disorders and Stroke ( estimates that there are over 600 brain disorders and the World Health Organization is calling neurological disorders one of the greatest public health challenges today. Among the neurological disorders, over half of the burden of having a disorder is contributed to by cerebrovascular disease, 12% by Alzheimer's and other dementias, and 8% by epilepsy and migraine. Neurological disorders are a significant cause of mortality, contributing to over 12% of the total deaths globally.

General Changes
One study found that Chronic Fatigue Syndrome (per Fukuda & Canadian Consensus Criteria) is associated with decreases in white matter, gray matter and blood volume deficits in the brain, which continue to deteriorate at an abnormal rate.

Microglia

 * "Microglia in Fibromyalgia & Chronic Fatigue Syndrome", About Health, 22 Feb 2016.
 * see also Low Dose Naltrexone