The 3Ps model

The 3Ps model or Cognitive Behavioral Model (CBM) of chronic fatigue syndrome is a theory that proposes that CFS can be explained by predisposing, precipitating and perpetuating factors.

The 3Ps model is a biopsychosocial hypotheses, and has been used to justify the use of a form of psychotherapy called cognitive behavioral therapy in patients with ME/CFS, irrespective of whether a co-existing mental illness is present.



Evidence
The controversial PACE trial was the largest trial of cognitive behavioral therapy and graded exercise therapy, and was based on the cognitive behavioral model of chronic fatigue syndrome. Two of the three PACE trial principle investigators, Trudie Chalder and Michael Sharpe, were among the original authors of the CBM for CBT and both authored or co-authored books on the approach prior to the PACE trial. The PACE trial initially reported moderate improvements in symptoms, but a later Freedom of Information Act request provided crucial data that disputed this.

Criticism
The 3Ps model has been described as fundamentally flawed.

Books
1989, Chronic Fatigue and its Syndromes

Notable studies

 * 1989, Management of chronic (post-viral) fatigue syndrome (Full text)
 * 1995, Chronic fatigue syndrome: A cognitive approach (Full text)
 * 2005, A population-based study of chronic fatigue syndrome (CFS) experienced in differing patient groups: An effort to replicate Vercoulen et al.'s model of CFS (Full text)


 * 2019, The ‘cognitive behavioural model’ of chronic fatigue syndrome: Critique of a flawed model (Full text)

Learn more

 * The ‘cognitive behavioural model’ of chronic fatigue syndrome: Critique of a flawed model