Acetylcholine

Acetylcholine is a neurotransmitter.

Acetylcholine is also used as a neurotransmitter in the autonomic nervous system, both as an internal transmitter for the sympathetic nervous system and as the final product released by the parasympathetic nervous system.

A large Germany study found 29% of ME/CFS patients had elevated autoantibodies to acetylcholine receptors.

Anecdotally, some patients have tried Mestinon, an acetylcholine reuptake inhibitor used to treat myasthenia gravis, with some success.