Armadillo Like Helical Domain Containing 4

Armadillo Like Helical Domain Containing 4 or ARMH4 or C14orf37 is a gene that may be linked to chronic fatigue syndrome. https://www.genecards.org/cgi-bin/carddisp.pl?gene=ARMH4

ME/CFS
The first publication from the long term ME/CFS Gene Study, which used the Fukuda criteria for chronic fatigue syndrome only, looked for the SNPs that were more common in CFS patients than in healthy people, and which were most likely to be harmful. C14orf37 was one of the top ten genes most likely to be harmful thatmore common in CFS patients, occurring in over 70% of patients.

Notable studies

 * 2019 - Genetic Predisposition for Immune System, Hormone, and Metabolic Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study (Full text)

Learn more

 * ARMH4 - Genecards