Two day exercise test

Theory
The hypothesis is that ME/CFS patients are almost unique in having a severe deterioration in the second of two CPET (Cardiopulmonary exercise test) exercise tests on consecutive days.

Evidence

 * 2014, Inability of myalgic encephalomyelitis/chronic fatigue syndrome patients to reproduce VO₂peak indicates functional impairment (Betsy Keller)
 * 2013, Discriminative validity of metabolic and workload measurements for identifying people with chronic fatigue syndrome (Christopher Snell, Staci Stevens, Davenport TE, Mark VanNess)

Cost & availability
Cost is $2200. Because they are based in a college setting (not healthcare setting), they cannot process insurance (including Medicare or Medicaid), so the patient would need to work directly with their insurer about reimbursement. (private email)
 * Workwell Foundation (United States, CA)
 * Betsy Keller at Ithaca College (United States, NY)

Talks & interviews

 * 2014, Mark VanNess 'Exercise and ME/CFS' at Bristol Watershed. Part One

Learn more
2013, [http://www.cortjohnson.org/blog/2013/07/30/busted-exercise-study-finds-energy-production-system-is-broken-in-chronic-fatigue-syndrome/ Busted! Exercise Study Finds Energy Production System is Broken in Chronic Fatigue Syndrome]

2013, Repeat Test Reveals Dramatic Drop in ME/CFS Exercise Capacity