PACE Trial Steering Committee

The PACE Trial Steering Committee (or TSC) was "responsible for the independent oversight of the progress of the trial, investigation of serious adverse events, and determining the future progress of the trial in the light of regular reports from the DMEC."

Members of the TSC
The PACE Trial Steering Committee members were:

Professor Janet Darbyshire (Chair),

Professor Jenny Butler (occupational therapist),

Professor Patrick Doherty (physiotherapist),

Dr Stella Harris (patient representative),

Dr Meirion Llewelyn (consultant physician in infectious diseases), and

Professor Tom Sensky (liaison psychiatrist and CBT therapist).

Observers include:

Professor Mansel Aylward (previously of Department for Work and Pensions),

Mr Chris Clark (Action for M.E.),

Peter Craig (Scottish Executive),

Dr. Moira Henderson Department for Work and Pensions

Susan Lonsdale (DH) and

Dr Sarah Perkins Medical Research Council

Professor Stephen Stansfeld (Queen Mary University of London, on behalf of the sponsor).

Dr Alison Wearden (Principal Investigator of the FINE trial, an MRC funded, sister study to PACE also researching CFS/ME).

Other members include the three investigators, the trial statisticians, and the trial manager (secretary to the committee).

The Medical Research Council approved the members of the PACE Trial Steering Committee.

Previous members/observers
Dr Robin Buckle Medical Research Council

Professor Clair Chilvers (R&D, DH)

Data Monitoring and Ethics Committee (DMEC)

The Data Monitoring and Ethics Committee (DMEC) is independent and responsible for monitoring progress of the trial and serious adverse events and reactions. The DMEC will meet annually or more often if the chair determines a reason for doing so, and provide a trial progress report at the end of each meeting which will be sent to the TSC. The DMEC is composed of:

Professor Paul Dieppe (chair),

Dr Charlotte Feinmann (liaison psychiatrist) and

Professor Astrid Fletcher (epidemiologist).

PACE Trial Management Group
The separate PACE Trial Management Group (TMG) was "responsible for the day-to-day running and management of the trial".

First wave therapists
Therapists involved in piloting the therapies

Vincent Deary (CBT)

Nicola Dyer (GET)

Sally Ludlum (APT)

Louise Mason (APT)

Bella Stensnas (CBT)

Claire Topfer (GET)

Tracey Turner (GET)

Sally Wagner (APT)

Sue Wilkins (CBT)

Giselle Withers (CBT)