Vascular endothelial growth factor

Vascular Endothelial Growth Factor (VEGF) or Vascular Endothelial Growth Factor A (VEGF-A) is a signal protein produced by cells that stimulates blood vessel formation (vasculogenesis and angiogenesis). Vascular Endothelial Growth Factor was originally known as vascular permeability factor (VPF).

The VEGF family help maintain blood vessel and lymphatic systems.

ME/CFS
Landi et al. (2016) found lower levels of VEGF, IL-7 and IL-16 in 100 long-term ME/CFS patients compared to controls but studies by Horning et al. (2015) and Montoya et al. (2017) did not find this statistically significant.

Notable studies

 * 2016, Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome

Learn more

 * 2016, VEGF: Its Role in Inflammation, Heart Disease, Cancer and Brain Function