T cell immunoreceptor with Ig and ITIM domains

TIGIT or T Cell Immunoreceptor With Ig And ITIM Domains, alternatively known as WUCAM or Vstm3 or VSIG9 is a protein and antibody which has an important role in the immune system. The gene that encodes the TIGIT antibody may also be referred to as TIGIT.

Function
TIGIT is an emerging immune checkpoint, and a number of drugs targeting TIGIT are undergoing clinical trials for a number of types of cancer.

Fibromyalgia
A 2021 study by Verma et al. using immune profiling that TIGIT may have an important role in fibromyalgia.

Notable studies

 * 2021, Unbiased immune profiling reveals a natural killer cell-peripheral nerve axis in fibromyalgia - (Abstract)

Learn more

 * TIGIT - Gene cards