Christopher Snell

Christopher Ronald Snell, PhD, is the Scientific Director of Workwell Foundation, Ripon, California. He directs the Pacific Fatigue Lab at the Department of Health, Exercise, and Sport Sciences, at the University of the Pacific, Stockton, California, USA.

IOM Committee on Diagnostic Criteria for ME/CFS
Dr Snell was a reviewer for the 2015 report produced by the Institute of Medicine's (IOM) Committee on Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).

Chronic Fatigue Syndrome Advisory Committee
Dr. Snell was Chair of the Health and Human Services's (HHS) Chronic Fatigue Syndrome Advisory Committee (CFSAC) committee from 04/01/07-04/01/11.

Open letter to The Lancet
Three open letters to the editor of The Lancet urged the editor to commission a fully independent review of the PACE trial, which the journal had published in 2011. In 2016, Dr. Snell, along with 42 colleagues in the ME/CFS field, signed the second letter. In 2018, Dr. Snell, with more than 100 colleagues in the ME/CFS field, signed the third letter.
 * Feb 10, 2016, An open letter to The Lancet, again - Virology blog
 * Jun 18, 2018, Trial By Error: An Open Letter to The Lancet, Two Years On

ME/CFS Common Data Element (CDE) Project
Member of the Quality of Life/Functional Status (CPET)/Activity Working Group of the Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Common Data Element (CDE) Project sponsored by the National Institute of Neurological Disorders and Stroke (NINDS) and the Centers for Disease Control and Prevention (CDC).

Notable studies

 * 2001, Assessment of Functional Impairment by Cardiopulmonary Exercise Testing in Patients with Chronic Fatigue Syndrome ABSTRACT
 * 2001, Chronic Fatigue Syndrome, Ampligen, and Quality of Life: A Phenomenological Perspective ABSTRACT
 * 2002, Physical performance and prediction of 2-5A synthetase/RNase L antiviral pathway activity in patients with chronic fatigue syndrome ABSTRACT
 * 2003, Subclassifying chronic fatigue syndrome through exercise testing ABSTRACT
 * 2004, Immunologic Aspects of Chronic Fatigue Syndrome: Report on a Research Symposium Convened by The CFIDS Association of America and Co-Sponsored by the US Centers for Disease Control and Prevention and the National Institutes of Health ABSTRACT
 * 2005, Exercise capacity and immune function in male and female patients with chronic fatigue syndrome (CFS) FULL TEXT
 * 2007, Legal and Scientific Considerations of the Exercise Stress Test ABSTRACT
 * 2007, Diminished Cardiopulmonary Capacity During Post-Exertional Malaise ABSTRACT
 * 2010, Post-exertional malaise in women with chronic fatigue syndrome ABSTRACT
 * 2010, Conceptual model for physical therapist management of chronic fatigue syndrome/myalgic encephalomyelitis ABSTRACTFULL TEXT
 * 2011, Reliability and validity of Short Form 36 Version 2 to measure health perceptions in a sub-group of individuals with fatigue ABSTRACT
 * 2011, Diagnostic accuracy of symptoms characterising chronic fatigue syndrome ABSTRACT
 * 2012, Minimum data elements for research reports on CFS FULL TEXT
 * 2013, Discriminative Validity of Metabolic and Workload Measurements for Identifying People With Chronic Fatigue Syndrome FULL TEXT
 * 2018, Editorial - Checking our blind spots: current status of research evidence summaries in ME/CFS. (Introduction)
 * 2018, Cardiopulmonary Exercise Test Methodology for Assessing Exertion Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Abstract
 * 2019, Chronotropic Intolerance: An Overlooked Determinant of Symptoms and Activity Limitation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome? (Full text)
 * 2019, Whole blood human transcriptome and virome analysis of ME/CFS patients experiencing post-exertional malaise following cardiopulmonary exercise testing (Full text)

Talks and interviews

 * 2011, National Institutes of Health (NIH) State of the Knowledge Workshop regarding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Research presenter
 * Cardiopulmulmonary Exercise Testing to Assess fatigue in ME/CFS (presentation starts at the 8:02:00 time marker)


 * 2016, 12th International IACFS/ME Biennial Clinical and Research Conference, Emerging Science and Clinical Care, How Cardiopulmonary Exercise Testing Informs Pathology and Treatment(Workshop given with Mark VanNess, Ph.D. and Betsy Keller, Ph.D.)

Learn more

 * 2012, Clinical exercise testing in CFS/ME research and treatment