Macrophagic myofasciitis

Macrophagic myofasciitis or MMF is a rare condition that causes chronic fatigue and muscle pain, and may result in patients being diagnosed with chronic fatigue syndrome. It is regarded as a form of autoimmune syndrome induced by adjuvants (ASIA).

Signs and symptoms

 * Widespread muscle pain
 * Chronic fatigue
 * Cognitive dysfunction (brain fog)
 * Weakness at the site of a vaccine
 * Raised level of creatine kinase
 * Raised level of erythrocyte sedimentation rate https://books.google.com/books/about/Textbook_of_Pediatric_Rheumatology_E_Boo.html?id=oEemcpeEufoC

Diagnosis
A muscle biopsy at the site of the vaccine

ME/CFS
Many patients with MMF meet the now disused Oxford criteria for chronic fatigue syndrome, or the more commonly used Fukuda criteria.

Notable articles

 * 2003, Chronic fatigue syndrome in patients with macrophagic myofasciitis - (Full text)
 * 2006, Atypical presentation of macrophagic myofasciitis 10 years post vaccination - (Full text)
 * 2009, A role for the body burden of aluminium in vaccine-associated macrophagic myofasciitis and chronic fatigue syndrome - (Full text)
 * 2014, Clinical features in patients with long-lasting macrophagic myofasciitis - (Full text)