Prostaglandin

Prostaglandins are a subclass of eicosanoids derived from long chain fatty acids.

Prostaglandins are involved in a diverse range of functions including vasodilation, uterus contraction, pain, gastric acid secretion, and autonomic neurotransmitters.

Prostaglandins can also by pyrogenic.

Synthesis
They are found in almost all cells with a nucleus. They are produced by the oxidation of arachidonic acid, DGLA or EPA from the cell membrane by phospholipase A2.

Exercise
In healthy people, Prostaglandin E2 levels are raised significantly for days after exercise.