Mitochondrion

Mitochondria are organelles found in of the cells in the human body. They generate most of a cell's energy or ATP. Mitochondria have their own independent genome called mitochondrial DNA.

Chronic fatigue syndrome
There is ample evidence of mitochondrial dysfunction in Chronic Fatigue Syndrome patients. Muscle biopsies have shown evidence of mitochondrial degeneration, deletions of mitochondrial DNA , and the reduction of mitochondrial activity.