Malic acid

Malic acid is an intermediate in the citric acid cycle. Malic acid is found in apples.

Fibromyalgia

 * 2009, Management of Fibromyalgia: Rationale for the Use of Magnesium and Malic Acid (non-blinded)
 * While these results are promising, a subsequent double-blind crossover study of primary fibromyalgia patients who received 300 mg magnesium and 1200 mg malic acid or placebo in random order for four weeks, each with a two-week washout period in between, failed to find significant improvements in pain, tenderness, and functional or psychological measures