MEpedia:Science guidelines

Thank you so much for deciding to contribute to MEpedia, and for rolling up your sleeves to work on the science! Let's dive right in.

Not sure where to start? Try our How to contribute page after this one.

Goals
The basic goals of an MEpedia science article are to:


 * Inform the reader of the basics
 * Provide resources via links and citations so the reader can learn more

Start with a one-paragraph summary
At the start of every article on MEpedia, there should be a plain-language summary of the content below. Sometimes, it is easier to write the summary last; you will have a much clearer conception of the main idea once the rest of your writing is done. The summary should appear above any sections you create, making it show up above the table of contents.

Outlines
You can find MEpedia article outlines for potential treatments, medical hypotheses, and body systems, e.g.. Just copy the outline (Ctrl-C) and paste it (Ctrl-V) into the article to have a template you can use.

Just the facts
Science writing should be about what we know to be true, so far as our current understanding of science can tell us.

It's important to omit descriptive words that encourage the reader to think in a certain way, such as adjectives and adverbs. For example, "intriguingly", "disastrously", and other adverbs inform the reader what they ought to think about the next piece of information. The facts must speak for themselves.

Aim as close to the objective truth as possible.

Avoid the omission of credible sources with which you may disagree.

Less is more
The goal of an MEpedia page is to inform the reader of the basics and link out to resources that will provide a more thorough grounding in the topic. To best serve our community in the long run, that may mean reading a long article and typing one sentence (or even one phrase!) into MEpedia.

If you aren't certain how to interpret a study or summarize it, you may be able to find more information if you look on Phoenix Rising or Science for ME and search for the study's title in quotes. Often there will be a thread with detailed discussions of the study's implications. You may also check out the MEpedia Project Facebook group and chat about the study there.

Do your best to avoid cutting and pasting, or paraphrasing blocks of information. Find the simplest way to convey the information so that brain-fogged readers can understand.

Use equivocal language
Recognize that scientific fact changes by using equivocal language: "it may be that..." "it is possible that..." are good examples. Avoid language like "it has been proved" or "we now know".

Types of studies
The type of biological sample used in the study can have a dramatic effect on whether or not the results of the study are accurate for human beings. The following are displayed from least to most applicable to human beings.


 * 1) In vitro: In vitro studies refer to studies performed on cells or tissues that have been removed from the organism. This could mean cells in a petri dish, blood removed from a patient, or tissue grown in a lab. While these studies can point in the right direction, the premises they introduce must be tested in a living thing before they are fully accepted.
 * 2) In vivo: In vivo studies refer to any study performed on tissues, cells, or organs within the living organism:
 * 3) In an organism not a mammal   The results of these studies, even perfectly performed, may have very little relationship to what might occur in a human being
 * 4) In a mammal but not a human  While rat and mouse studies are very common, and may lead to greater insight into biological processes, rat and mouse physiology differs significantly from that of human physiology.  The immune system in particular is very different in a mouse versus a human.
 * 5) In a human   When possible, always look for studies performed in human beings rather than in any other category.  In Pubmed, after you search for a topic you will see a list of modifiers scrolling down the left-hand side of your page.  One of these will say Species: Humans.  By clicking on this, you will only see studies performed on human cell lines, tissues, or on humans in vivo.

Citation
Even if you are certain it is true, if you can't cite it, you can't say it.

Suggested Sources
See  What counts as an academic source  (Monash University)

General topics (tertiary sources)
 * MSD Manuals - Consumer (basic topics) or Professional editions
 * Merckx Manuals
 * Medline Medical Encyclopedia
 * Merriam-Webster Medical Dictionary

Image sources:
 * NHS Health Conditions (UK health service)
 * British National Foundry - drug reference guide for UK doctors
 * Drugs.com - medications, side effects, brand & generic names
 * WikiMedia Commons
 * Public Health Image Library - CDC
 * Google advanced images search - use the  images for re-use  option

Tertiary/secondary vs primary sources
If you have worked on medical pages on Wikipedia before, you may be aware that they encourage the use of reference books (tertiary sources), and review articles (secondary sources). There are few review articles on ME/CFS, so it is acceptable to cite primary sources, so long as you use the equivocal language described above.

Seminal works and the age of works
The goal in scientific writing is to represent the most up-to-date information. For that reason, in biomedical research it's important to make the attempt to find primary and secondary sources that were published in the past several years.

An exception to this general guideline are seminal works. A seminal work is a publication that changes the way the field thinks about a topic. Did your source define something new or introduce a novel idea? If so, it may be a seminal work.

A second exception are works that focus on history or discuss a sequence of events as an important aspect of the narrative.

A good example in ME might be the Fukuda paper (1994) that presented a working definition for 'CFS'. Because it defines something new, it makes sense to cite it even in a modern paper, or in an article that discusses the history of ME.

When should I cite?
According to Citing References in Scientific Research Papers, "You should acknowledge a source any time (and every time) you use a fact or an idea that you obtained from that source. Thus, clearly, you need to cite sources for all direct quotations. But you also need to cite sources from which you paraphrase or summarize facts or ideas -- whether you've put the fact or idea into your own words or not..."

Remember Wikipedia is not a reliable source
On many subjects, Wikipedia is an excellent trove of sources that may prove useful. However, by its own description, Wikipedia itself is not a reliable source: "'Wikipedia can be edited by anyone at any time. This means that any information it contains at any particular time could be vandalism, a work in progress, or just plain wrong...There are many errors that remain unnoticed for days, weeks, months, or even years. Therefore, Wikipedia should not be considered a definitive source in and of itself.'" Instead, check claims on Wikipedia to see if they are verified by a reliable source. If they are, add the information citing that source instead.

How to cite



 * 1) First, check out the top menu running right alongside the MEpedia logo and find the button that says 'cite'.
 * 2) When you click the 'cite' button, you should see a drop-down menu that offers you options, depending on whether you are citing a website, a book, a news article, a scientific journal, a basic reference, or to re-use a previous reference.
 * 3) Mepedia journal cite 2.png journal for any scholarly source. Scholarly sources are anything from pubmed or a scientific journal online or in print.
 * 4) Use news for anything from a news outlet or a blog discussing the news. Note: if a news article or blog is discussing science, go back to the original source (the journal) and use the information you find in that original source.  Don't count on the writer of the blog to have gotten it right!
 * 5) Use basic when you aren't sure what category to use.
 * 6) Important time saver!  'Re-use' if you have already cited a source once in the same article.
 * 7) When you choose to cite a journal, the pop-up box at right will be displayed: You will see places to fill in the information you know about the article.  Items with an asterisk next to them mean you must enter that information.
 * 8) Often, the journal citation will have information like page number or issue number. Scientific journals may also have multiple authors, even though there is room for only a few in the drop-down menu provided.  If you scroll down to the bottom and click the 'add more information' button (circled at right), then you will be able to add that information easily.
 * 9) When you are finished, click the blue 'insert' button at the top right-hand side of the pop-up box.