Coenzyme Q10

Coenzyme Q10 (CoQ10) or ubiquinone is found in the mitochondria and as a component of the electron transport chain plays an important role in aerobic respiration.

Evidence
Plasma CoQ10 was found to be significantly lower in ME/CFS patients than in normal controls and correlated with symptom severity. A literature review found that CoQ10 was marginally deficient in people with chronic fatigue syndrome.

Ubiquinol-10 supplementation can improve autonomic nervous function and cognitive function in chronic fatigue syndrome.

Notable studies

 * 2000, Nutritional Strategies for Treating Chronic Fatigue Syndrome (Full text)


 * 2009, Coenzyme Q10 deficiency in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is related to fatigue, autonomic and neurocognitive symptoms and is another risk factor explaining the early mortality in ME/CFS due to cardiovascular disorder (Abstract)


 * 2016, Ubiquinol-10 supplementation improves autonomic nervous function and cognitive function in chronic fatigue syndrome (Abstract)

Learn more

 * 2016, CoQ10, B-Vitamins and CFS
 * Coenzyme Q10 Uses, Side effects and Dosage - WebMD