B cell

B cells or B lymphocytes are a type of white blood cell. They function in the humoral immunity component of the adaptive immune system by secreting antibodies.

Notable studies

 * 2009, Clinical impact of B-cell depletion with the anti-CD20 antibody rituximab in chronic fatigue syndrome: a preliminary case series (Øystein Fluge, Olav Mella)
 * 2011, Benefit from B-lymphocyte depletion using the anti-CD20 antibody rituximab in chronic fatigue syndrome. A double-blind and placebo-controlled study (Øystein Fluge, Olav Mella, Bruland O, Risa K, Storstein A, Kristoffersen EK, Sapkota D, Næss H, Dahl O, Nyland H)
 * 2013, Altered functional B cell subset populations in patients with chronic fatigue syndrome compared to healthy controls. (Full Text)
 * 2015, B-Lymphocyte Depletion in Myalgic Encephalopathy/ Chronic Fatigue Syndrome. An Open-Label Phase II Study with Rituximab Maintenance Treatment (Øystein Fluge, Olav Mella, Risa K, Lunde S, Alme K, Rekeland IG, Sapkota D, Kristoffersen EK, Sørland K, Bruland O, Dahl O)
 * 2015, Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome (Øystein Fluge, Olav Mella, Madlen Loebel, Patricia Grabowski, Heidecke H, Sandra Bauer, Hanitsch LG, Wittke K, Meisel C, Reinke P, Volk HD, Carmen Scheibenbogen)
 * 2016, Extended B cell phenotype in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A cross-sectional study (Full Text)
 * Jonathan Edwards comments on: Extended B-cell phenotype in patients with ME/CFS: A cross-sectional study (Link)
 * 2018, CD24 expression and B cell maturation shows a novel link with energy metabolism: potential implications for patients with ME/CFS (Faye Mensah, Chris Armstrong, Reddy, Bansal, Berkovitz, Leandro, and Cambridge)

Learn more

 * Wikipedia - B cell
 * Crash Course - The Immune System Part 2 (Humoral immunity & B cells)
 * 2016, First Paper Published from IiME-funded Research at UCL - Layman's Summary (Invest in ME)