Neurology of ME/CFS

Volume
One six year longitudinal study (published in 2016) found that Chronic Fatigue Syndrome (per Fukuda criteria & Canadian Consensus Criteria) is associated with decreases in white matter, gray matter and blood volume deficits in the brain as compared to healthy controls.

A 2017 study, using segmented anatomical MRI brain scans showed that, adjusting for total intracranial volume, CFS patients (as per Fukuda diagnostic criteria) had larger gray matter volume and lower white matter volume. The increased gray matter volume was predominantly found in the amygdala and insula cortex. The decreased white matter was predominantly found in the midbrain and temporal lobe.

Microglia
Microglia

Electroencephalogram (EEG)
QEEG

Talks & interviews

 * 2016, 79. ME & inflammation, part 1 / ME & inflammatie, deel 1 - Dr Harrison (Neil Harrison)
 * 2016, 78. ME & the brain, part 2 / ME & de hersenen, deel 2 - Dr. Neil Harrison (Neil Harrison)
 * 2016, 77. ME & the brain, part 1 / ME & de hersenen, deel 1 - Dr. Neil Harrison (Neil Harrison)

Learn more

 * 2016, Laggard: Is an Under-Active Brain the Problem in Chronic Fatigue Syndrome (ME/CFS)