Creatine

Creatine is a nitrogenous organic acid that helps supply energy to all cells in the body, especially muscle. It increases the formation of ATP. It is produced from the amino acids glycine and arginine.

Raised urinary creatine excretion was found in two, separate outbreaks of myalgic encephalomyelitis in New York State in 1950 and in 1961. Creatine was high during periods of relapse and normal during periods of recovery.