Thrombospondin-1

Thrombospondin-1, also known as TSP-1 or Thbs1 is a glycoprotein, and that raised TSP-1 may be linked to post-exertional malaise and brain fog.

ME/CFS
In October 2020, the Open Medicine Foundation announced the STOP-ME study to investigate the role of TSP-1 in ME/CFS, and TSP-1 as a possible therapeutic target for ME/CFS.

Learn more

 * Study of Thrombospondin-1 (TSP1) in ME / CFS pathogenesis (STOP-ME) - Open Medicine Foundation