MEpedia:Contents

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The Disease
Infectious agents: Herpesvirus Epstein barr virus cytomegalovirus HSV-1 HSV-2 influenza HHV-6 HHV-7 Coxsackie A Coxsackie B Babesia Bartonella enterovirus Parvovirus B-19 Ross River Virus Borna Disease Virus Q Fever H1N1

Triggers and risk factors: Viral onset Trauma Pregnancy Menstrual cycle Stress Vaccine Toxic exposure Candidiasis Mold Epidemiology

Signs and symptoms: Orthostatic intolerance Ataxia Cognitive dysfunction Postural orthostatic tachycardia Neurally mediated hypotension Sleep disturbance Fatigue Post-exertional malaise Nonepileptic seizure Seizure Migraine Muscle fatigability Food intolerance Optical dysfunction

Medical hypotheses: Methylation cycle hypothesis Amygdala hypothesis Hygiene hypothesis Viral onset hypothesis Microbiome hypothesis Fatty acid hypothesis

Body systems: Nervous system HPA axis Brain Spinal cord Neuroinflammation Microglia Leaky brain Glutamate excitotoxicity Central sensitization Gastrointestinal system Microbiome Leaky gut Immune system Mucosal immune system B cell Natural killer cell Macrophage Cytokines IL-2 interferon IL-10 IL-1 IL-18 IL-17 Tumor necrosis factors Ribonuclease L Antibody Autoantibody Cardiovascular system Blood

Tests: Cardiopulmonary exercise test Two day exercise test Erythrocyte sedimentation rate C reactive protein Brain imaging MRI SPECT Exercise Tilt Table

Citizen science: 23andMe UBiome American Gut Mendus Any Treatment Phoenix Rising

Biochemistry and cell biology: Methylation cycle Citric acid cycle Mitochondria D lactate Lactic acid Nitric oxide Glutathione glucocorticoid endocannabinoid Histamine Tyrosine Phenylalanine

Nutrients: Vitamin D Vitamin C Copper Folate B12 B6 B2 Deadlock quartet TMG Sam-e L-carnitine Zinc Magnesium

Neurotransmitters and hormones: Neurotransmitters Serotonin Acetylcholine Dopamine Norepinephrine Epinephrine Melatonin Histamine Oxytocin Vasopressin Glutamate Hormones Cortisol Prostaglandins glucocorticoid progesterone estrogen testosterone estriadol calicitriol calcidiol

Names & Definitions
Names: Myalgic Encephalomyelitis Chronic Fatigue Syndrome ME/CFS Systemic Exertion Intolerance Disease Chronic epstein barr

Related conditions: Chronic lyme disease Mold illness Biotoxin illness Environmental illness Multiple Chemical Sensitivity Gulf War Illness Mast cell activation disorder Mastocytosis Ehlers Danlos Syndrome Fibromyalgia Small intestine bacterial overgrowth Lactic acidosis Autoimmune disease Cancer Thyroid disease Non-Hodgkin's lymphoma Multiple Sclerosis Dysautonomia

Definitions: Definitions of ME and CFS Canadian Consensus Criteria International Consensus Criteria Oxford criteria Fukuda criteria Holmes criteria Ramsay definition London criteria Nightingale definition

Treatment
Supplements: Probiotics AHCC CoQ10 MitoQ PrescriptAssist Mutaflor GcMAF Colostrum Transfer factors Fish oil EPA DHA

Antivirals: Valgancyclovir Famciclovir Valaciclovir Acyclovir Immunovir

Immuomodulators and immunostimulants: Ampligen Low dose naltrexone Equilibrant Intravenous immunoglobulin Staphylococcal vaccine

Anti-inflammatory drugs:

Other drug treatments: Rituximab Prednisone

Diets: Vegan diet Vegetarian diet Paleo diet Ketogenic diet GAPS diet Specific carbohydrate diet

Uncategorized interventions: Mold avoidance Fasting Chelation Fecal matter transplant Helminth therapy Pacing Energy envelope Dark chocolate Medical marijuana Hyperbaric oxygen Ozone Altitude Coffee enema Exercise Faecal bacteriotherapy

Clinical Doctors, USA: Lucinda Bateman Derek Enlander Nancy Klimas Courtney Craig Daniel Peterson Phillipe Bottello John Chia Jacob Teitelbaum

Clinical Doctors, UK: Sarah Myhill William Weir Nigel Speight Peter Behan Charles Shepherd Gabrielle Murphy Amolak Bansal

Clinical Doctors, Germany: Anna Dorothea Hoeck Prof. Dr. Carmen Scheibenbogen

Clinical Doctors, Belgium: Kenny de Meirleir

Clinical Doctors, South Africa: Cecile Jadin

Clinical Doctors, Sweden: Carl-Gerhard Gottfries

Research
Notable Studies

 Research initiatives USA: Open Medicine Foundation Chronic Fatigue Initiative Stanford ME/CFS Initiative Solve ME/CFS Microbe Discovery Project Bateman Horne Center Workwell Foundation Center for Infection & Immunity

 Researchers USA: Ronald Davis Jarred Younger Alan Light Andreas Kogelnik Jose Montoya David Bell Mady Hornig Eric Schadt Ian Lipkin John Chia Rosemary Underhill Suzanne Vernon David Berg Nancy Klimas Dane Cook Staci Stevens Mark VanNess Christopher Snell Zaher Nahle Rich Van Konyenburg Judy Mikovits

 Research initiatives Europe: ME Research UK Cure ME Invest in ME UK CFS/ME Collaborative Invest in ME Conference Ramsay Research Fund European ME Research Group

 Researchers UK: Melvin Ramsay Donald Acheson Gordon Parish Jonathan Kerr Amolak Bansal Julia Newton Elizabeth Dowsett Simon Carding James Mowbray John Richardson Luis Nacul Derek Pheby

 Researchers Australia: Elaine DeFreitas Sonya Marshall-Gradisnik Donald Staines

 Researchers Germany: Prof. Dr. Carmen Scheibenbogen

 Researchers Norway: Olav Mella Øystein Fluge

 Researchers Canada: Byron Hyde

Psychological Paradigm
Psychological paradigm, mind-body approaches and related interventions: PACE trial graded exercise therapy cognitive behavioral therapy biopsychosocial deconditioning Mickel therapy Lightning process Gupta programme Psychoneuroimmunology Meditation Bodily distress syndrome Functional somatic syndrome Psychosomatic illness Neurasthenia Medically unexplained symptoms

Psychological paradigm proponents: Simon Wessely Michael Sharpe Peter White Trudie Chalder Rona Moss-Morris Jessica Bavinton Esther Crawley

Psychological paradigm critics: James Coyne Keith Laws David Tuller Ronald Davis Bruce Levin Arthur Reingold Jonathan Edwards Leonard Jason Ellen Goudsmit

Politics & Government
US Government: Institute of Medicine report Pathways to prevention report Trans-NIH Working Group National Institutes of Health Centers for Disease Control & Prevention

UK Government: National Institute for Health and Care Excellence National Health Service Science Media Centre

Disease Funding: Money and ME, patient analysis Science Magazine chart showing relative ME/CFS funding

Disability & Insurance
Medical Insurers: UNUM

History
Outbreaks: List of outbreaks Incline village Lydonville Akureryi Los Angeles Royal Free Hospital

Deceased patients: Sophia Mirza Vanessa Li Lynn Gilderdale Emily Collingridge Chardale Dotson Irvine

Patient Advocacy
Patient Groups: #MEAction ME Association Tymes Trust Irish ME/CFS Association ME Advocacy Change For M.E. Change For Us

Notable patients: Karina Hansen Joanne Sophia Mirza Lynn Gilderdale Emily Collingridge Whitney Dafoe Tom Kindlon Graham McPhee Jennie Spotila Laura Hillenbrand Martin McCutcheon Naomi Whittingham Jane Colby Countess of Mar Brian Vastag Jennifer Brea Ryan Prior Hillary Johnson Julie Rehmeyer Leonard Jason Charles Shepherd Nasim Marie Jafry Ken Lassesen Cort Johnson Valerie Eliot Smith Doctor Speedy Tanya Marlow Deborah Waroff Beth Mazur Catherine Hale Stuart Murdoch Mary Schweitzer Toni Bernhard Frank Twisk

Notable healthy advocates: Angela Kennedy Mary Dimmock Greg Crowhurst Malcolm Hooper

Notable Quotes: Quotes

Journals, TV, Film, Books, Interviews, Blogs
Journals:
 * The Lancet
 * The BMJ

Books:
 * Plague
 * The State of Me
 * Love and Fatigue in America
 * Osler's Web
 * America's Biggest Cover-Up
 * Authors of our own misfortune

Films:
 * What About ME
 * I Remember Me
 * Forgotten Plague
 * Canary in a Coal Mine
 * About: "Jennifer, a Harvard PhD student, was signing a check at a restaurant when she found she could not write her own name. Months before her wedding, she became progressively more ill, losing the ability even to sit in a wheelchair. When doctors insisted that her condition was psychosomatic, she picked up her camera to document her own story and the stories of four other patients struggling with the world’s most prevalent orphan disease." (Source: http://www.canaryinacoalminefilm.com/about/)
 * The Last Great Medical Cover Up

Notable TV segments:
 * Sick and Tired BBC Alba 2012 documentary Toxic Tiredness, featuring Peter Behan Charles Shepherd Nasim Marie Jafry

Video Interviews:
 * ME/CFS Alert
 * Science for Patients

Blogs:
 * Health Rising A great resource to patients. "Health Rising is dedicated to providing timely, accurate information to people with chronic fatigue syndrome (ME/CFS) and fibromyalgia. Founder Cort Johnson came down with chronic fatigue syndrome/fibromyalgia around 1980 while at the University of Santa Cruz. He received a BA in Philosophy from Cal State Long Beach in the late 1980’s and an MS in Environmental Studies from San Jose State University around 2000. Committed to create a site devoted to understanding chronic fatigue syndrome research and treatment options he opened a very basic (Frontpage) content based site around 2004 called Phoenix Rising.  Soon afterwards a newsletter was added. By 2010 with the addition of a blog and a Forum package and hundreds of articles/blogs, Phoenix Rising had become the most visited website devoted to ME/CFS on the internet. In August 2010 Phoenix Rising became a non-profit corporation." (Source: http://www.cortjohnson.org/about-us/)
 * Occupy CFS
 * MEAction "#MEAction is an international network of patients empowering each other to fight for health equality for Myalgic Encephalomyelitis. #MEAction is not structured like a traditional advocacy organization or patients’ association. We are primarily a platform, designed to empower patients advocates and organizations, wherever they might be, with the technological tools and training to do what they are already doing – better. We were founded with the belief that while we may find it difficult to advocate for ourselves in the physical world, in the virtual world, we can be an unstoppable force." (Source: http://www.meaction.net/about/)
 * ME Advocacy
 * Courtney Craig
 * Cell Fatigue
 * CFS Patient Advocate
 * Constant F****** S***
 * ME Association
 * Onward Through the Fog
 * Nice Guidelines
 * Valerie Eliot Smith Blog
 * CFS Remission
 * About.com Health FMS/ME/CFS

'Discussion Forums'
 * Phoenix Rising