Peripheral blood mononuclear cell

Peripheral Blood Mononuclear Cells or PBMCs are types of white blood cells with a round nuclei, including lymphocytes, macrophages and monocytes, but not granulocytes (polymorphonuclear leucocytes like neutophils, eosinophils and basophils).

PBMCs are less dense than granulocytes, and less dense than red blood cells.

Notable studies

 * 2001, G-Actin Cleavage Parallels 2-5A-Dependent RNase L Cleavage in Peripheral Blood Mononuclear Cells—Relevance to a Possible Serum-Based Screening Test for Dysregulations in the 2-5A Pathway (Abstract)


 * 2017, Novel characterisation of mast cell phenotypes from peripheral blood mononuclear cells in chronic fatigue syndrome/myalgic encephalomyelitis patients (Full Text)


 * 2018, A new approach to find biomarkers in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) by single-cell Raman micro-spectroscopy (Abstract)


 * 2018, A nanoelectronics-blood-based diagnostic biomarker for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) (Full text)