Lyrica

Lyrica is the brand name for pregabalin, a prescription medication used to treat fibromyalgia, diabetic nerve pain, pain after shingles, spinal cord injury nerve pain, and partial onset seizures in adults (an add-on treatment) with epilepsy.

Lyrica is manufactured by the USA pharmaceutical company, Pfizer, Inc.

Prescribed for various conditions

 * Lyrica and Cymbalta Recommended for Diabetic Neuropathy (Diabetic nerve pain.) via Pain News Network
 * Lyrica for Fibromyalgia via WebMD
 * How does Lyrica treat nerve pain from shingles? via Share Care
 * FDA Approves Lyrica For The Management Of Neuropathic Pain Associated With Spinal Cord Injury Based On Priority Review via Pfizer Press Release
 * FDA Approves Pregabalin as Epilepsy Add-On Treatment for Partial Onset Seizures via P&T Community

Side Effects
This information contains side effect information about pregabalin, Lyrica's active ingredient. Some of the dosage forms listed on this page may not apply to the brand name Lyrica.

Always review a drug company's prescription drug's side effects and possible drug interactions with your doctor and pharmacist.

Pregnant women must always consult with their doctor and pharmacist when taking any prescription drug, over-the-counter drug, supplement, or herbal remedy for side effects, drug interactions, and possible miscarriage, injury, birth defect, addiction, or death to the embryo, fetus, or baby. Breastfeeding women should always talk to their doctor and pharmacist for information about breast milk being laced with the drug she has taken causing side effects, injury, addiction, or death, and drug interactions to the baby consuming her breast milk.

Check with your doctor and pharmacist before using any prescription or over-the-counter drug, supplement, or herbal remedy being administered to a child. Check with your doctor for children's side effects or drug interactions that may not be listed.

More commonly reported ones are:

 * Accidental injury
 * bloating or swelling of the face, arms, hands, lower legs, or feet
 * blurred vision
 * burning, tingling, numbness or pain in the hands, arms, feet, or legs
 * change in walking and balance
 * clumsiness
 * confusion
 * dementia
 * difficulty having a bowel movement
 * difficulty with speaking
 * double vision
 * dry mouth
 * false beliefs that cannot be changed by facts
 * fever
 * headache
 * hoarseness
 * increased appetite
 * lack of coordination
 * loss of memory
 * lower back or side pain
 * painful or difficult urination
 * problems with memory
 * rapid weight gain
 * sensation of pins and needles
 * shakiness
 * sleepiness
 * stabbing pain
 * trembling, or other problems with muscle control or coordination
 * unsteady walk
 * unusual drowsiness
 * unusual weight gain or loss

Less commonly reported ones are:

 * Anxiety
 * bloated or feeling of fullness
 * chest pain
 * cold sweats
 * cool, pale skin
 * cough producing mucus
 * decrease or change in vision
 * depression
 * excess air or gas in the stomach or intestines
 * eye disorder
 * false or unusual sense of well-being
 * general feeling of discomfort or illness
 * increased hunger
 * loss of appetite
 * loss of bladder control
 * loss of consciousness
 * loss of strength or energy
 * muscle aches, twitching or jerking, or weakness
 * nausea
 * nervousness
 * nightmares
 * noisy breathing
 * pain
 * passing gas
 * rhythmic movement of the muscles
 * runny nose
 * seizures
 * shivering
 * slurred speech
 * sweating
 * trouble sleeping
 * twitching
 * uncontrolled eye movements
 * vomiting

Other less commonly reported ones are:

 * Difficult or labored breathing
 * tightness in the chest

Rarely reported ones are:

 * Blistering, peeling, or loosening of the skin
 * chills
 * cough
 * diarrhea
 * difficulty with swallowing
 * dizziness
 * fast heartbeat
 * hives, itching, skin rash
 * joint or muscle pain
 * puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
 * red skin lesions, often with a purple center
 * red, irritated eyes
 * sore throat
 * sores, ulcers, or white spots in the mouth or on the lips
 * unusual tiredness or weakness

Generic legal battle

 * Mar 2012, Pfizer blocked Israel-based Teva Pharmaceutical Industries and other manufacturers from selling generic versions of Lyrica.


 * Jul 2012, the U.S. Food and Drug Administration (FDA) approved a generic version of Lyrica. Pregabalin, the active ingredient, is the generic name. Two weeks after being approved by the FDA, marketing was blocked.


 * 2014, Pfizer Inc., the maker of Lyrica, successfully blocked the marketing of Pregabalin generics until December of 2018 arguing that the generics should not be marketed and made available until their patent ran out. Warner-Lamber, (a subsidieary of Pfizer), "still holds a “second medical use” patent for the use of pregabalin in the treatment of peripheral and central neuropathic pain, which expires in July 2017. A second medical use patent is one that relates to a new medical use for a known compound."

Lyrica patient assistance
These assistance programs come with various insurance coverage limitations and income thresholds.


 * Co-pay Card
 * Patient Assistance Program Check eligibility on Pfizer Rx Pathways

Learn more

 * Fibromyalgia
 * Frequently Asked Questions by Lyrica FAQ's for each condition Lyrica is prescribed for.