Donald Lewis



Dr Donald P. Lewis is a general practitioner specialising in ME/CFS working in Melbourne, Australia. He has been treating patients with ME/CFS, and researching the condition, since 1985.

International Consensus Criteria
Dr Lewis is one of the authors of the 2011 case definition, International Consensus Criteria.

Books

 * 2017, Chapter 31 - Sleep, Cognitive and Mood Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, in The Handbook of Stress and Health: A Guide to Research and Practice"'Abstract - Sleep abnormalities, neurocognitive disturbances and comorbid depressive symptoms are some of the particularly debilitating symptoms experienced by patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). This complex condition with currently evasive etiology involves a multisystemic symptom presentation that can reflect dysfunction in several organs and biological systems. The microbiota-gut-brain axis provides one possible pathway where dysfunction in communication between enteric microbiota, the gastro-intestinal system, and the brain may precipitate some ME/CFS symptoms. Sleep, neurocognitive and depressive symptoms are examined with recent microbiome research highlighting the potential etiological role of dysfunction in gut-brain communication. Treatment alternatives are reviewed with a focus on addressing underlying pathophysiology and possible causal mechanisms. The burgeoning field of microbiota research across diverse health fields provides an avenue of hope for future therapeutic advances and improved health outcomes for patients with ME/CFS."

Notable studies

 * 2018 - Open-label pilot for treatment targeting gut dysbiosis in myalgic encephalomyelitis/chronic fatigue syndrome: neuropsychological symptoms and sex comparisons (Full Text)
 * 2017 - Examining clinical similarities between myalgic encephalomyelitis/chronic fatigue syndrome and d-lactic acidosis: a systematic review (Full Text)
 * 2017 - The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome [
 * 2016 - Widespread pain and altered renal function in ME/CFS patients (Abstract)
 * 2016 - Support for the Microgenderome: Associations in a Human Clinical Population (Full Text)
 * 2015 - Sleep quality and the treatment of intestinal microbiota imbalance in Chronic Fatigue Syndrome: A pilot study (Full text)
 * 2015 - Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients
 * 2014 - Comorbidity of postural orthostatic tachycardia syndrome and chronic fatigue syndrome in an Australian cohort
 * 2009 - Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome

Clinic location
Dr Lewis founded the CFS Discovery clinic, which is in Donvale, Melbourne.

Talks and interviews

 * 2011 - Dr Don Lewis: Latest Understanding of ME/CFS (video)

Online presence

 * Website
 * PubMed
 * Twitter
 * Facebook
 * YouTube

Learn more

 * Wikipedia
 * Institution