Donald Lewis



Dr Donald P. Lewis (died 29 July 2019) was a general practitioner specializing in ME/CFS in Melbourne, Australia. He had been treating patients with ME/CFS and researching the condition since his wife became ill with ME/CFS in 1985.

International Consensus Criteria
Dr Lewis is one of the authors of the 2011 case definition, International Consensus Criteria.

Books

 * 2017, Chapter 31 - Sleep, Cognitive and Mood Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, in The Handbook of Stress and Health: A Guide to Research and Practice

Notable studies

 * 2009, Increased d-lactic Acid intestinal bacteria in patients with chronic fatigue syndrome
 * 2014, Comorbidity of postural orthostatic tachycardia syndrome and chronic fatigue syndrome in an Australian cohort
 * 2015, Sleep quality and the treatment of intestinal microbiota imbalance in Chronic Fatigue Syndrome: A pilot study - (Full text)
 * 2015, Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients
 * 2016, Widespread pain and altered renal function in ME/CFS patients - (Abstract)
 * 2016, Support for the Microgenderome: Associations in a Human Clinical Population - (Full Text)
 * 2017, Examining clinical similarities between myalgic encephalomyelitis/chronic fatigue syndrome and d-lactic acidosis: a systematic review - (Full Text)
 * 2017, The association of fecal microbiota and fecal, blood serum and urine metabolites in myalgic encephalomyelitis/chronic fatigue syndrome
 * 2017, Activin B is a novel biomarker for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) diagnosis: a cross sectional study - (Full text)
 * 2018, Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection
 * 2018, Open-label pilot for treatment targeting gut dysbiosis in myalgic encephalomyelitis/chronic fatigue syndrome: neuropsychological symptoms and sex comparisons - (Full Text) (Correction)
 * 2019, Post-Exertional Malaise Is Associated with Hypermetabolism, Hypoacetylation and Purine Metabolism Deregulation in ME/CFS Cases - (Full text)
 * 2019, An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients - (Abstract)

Clinic location
Dr Lewis founded the CFS Discovery clinic in Donvale, Melbourne, which has since closed.

Talks and interviews

 * 2011 - Dr Don Lewis: Latest Understanding of ME/CFS (video)
 * 01 Jun 2018 - Radio Interview - ABC Radio National (Australia) - Evenings with Christine Anu - What do we know about Chronic Fatigue Syndrome with Dr Donald Lewis & Dr Mark Guthridge (from timestamp 1:34:40 to 1:54:45)
 * 19 Aug 2019 - Trial By Error: My Interview with Melbourne’s Dr Don Lewis