Channelopathy hypothesis

Abhijit Chaudhuri and Peter Behan proposed that myalgic encephalomyelitis/chronic fatigue syndrome was an acquired neurological channelopathy illness, meaning that the symptoms are the result of ion channel transportation problems affecting the body's nervous system. The channelopathy hypothosis was first published in 1999.

Evidence
Ion transportation symptoms are recognized in the diagnostic criteria of the International Consensus Criteria.

Notable studies

 * 1999, Chronic fatigue syndrome is an acquired neurological channelopathy


 * 2000, The symptoms of chronic fatigue syndrome are related to abnormal ion channel function
 * 2003, Monitoring a Hypothetical Channelopathy in Chronic Fatigue Syndrome: Preliminary Observations