Abnormal neurovascular coupling

Neurovascular coupling (NVC) refers to the "regulation of cerebral blood flow to match brain activity, which is critically important for normal brain function".https://www.usc.edu.au/explore/usc-news-exchange/news-archive/2019/december/usc-research-to-diagnose-invisible-illness-faster Abnormal neurovascular coupling is a hypothesis being investigated to find out if it is underpinning cause of chronic fatigue syndrome. In 2019, Dr Zack Shan was awarded a grant to research neurovascular coupling in CFS.

Theory
According to Stewart et al. (2012) the cerebral perfusion may be contributing to the brain fog (neurocognitive dysfunction) found in patients with CFS may POTS.

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 * USC research to diagnose invisible illness faster - release