Serotonin norepinephrine reuptake inhibitor

Serotonin Norepinephrine Reuptake Inhibitors or Selective Serotonin-Norepinephrine Reuptake Inhibitors or SNRIs are a class of antidepressant medication used for depression, anxiety and sometimes other uses. Some SNRIs also licensed for chronic pain including nerve pain, e.g. cymbalta (duloxetine), fibromyalgia, or used off-label for other non-psychiatric conditions.

SNRIs include:
 * Duloxetine (brand name Cymbalta)
 * Milnacipran (Savella)
 * Venlafaxine (Effexor)

ME/CFS
SNRIs are ineffective as a primary treatment for ME/CFS, but may be used to treat some symptoms such as pain, or for co-existing conditions like reactive depression.

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 * SNRI antidepressants