Neuroinflammation

'''A concrete definition for neuroinflammation is not fully agreed on in the scientific world yet, but it is thought to follow similar patterns that inflammation in the rest of the body follows. Inflammation, in general, occurs when a pathogen, or something foreign to the body, gets into the body. The body detects the toxin with immune cells which then signal other immune cells to help eliminate the pathogen. The response and build-up of these immune cells is what is referred to as inflammation. The central nervous system (brain and spinal cord; CNS) are believed to do the same sort action with different types of cells. One of the main immune cells in the CNS is microglia, a type of brain cell that, when activated, signals other immune cells to help the brain fight diseases. This action is similar to how the body fights infection. Therefore, neuroinflammation is described as a combination of microglial activation and its response.

Neuroinflammation''' is inflammation of the nervous tissue, particularly the brain. Inflammation has been found in autopsies of ME/CFS patients. ME/CFS patients also have microglia activation.

Notable studies

 * Autopsies of four deceased ME patients showed various pathological phenomena in the central and peripheral nervous systems.
 * Brain Scans of ME/CFS from Stanford ME/CFS Initiative show inflammation. The New York Times article "Brains of People With Chronic Fatigue Syndrome Offer Clues About Disorder" has startling color images.

Talks & interviews

 * 2016, Do you have a hot brain?
 * 2016, What is neuroinflammation? (Jarred Younger)

Learn more

 * Wikipedia - Neuroinflammation