PACE trial documents

This page gives an overview of the main PACE trial documents. These include the PACE trial's full protocol, therapist manuals, participant newsletters and meeting minutes of the trial steering committee and trial management group.

Protocol

 * PACE trial protocol: Final version 5.0, 01.02.2006

For therapists

 * Cox et al. 2004. Manual for Therapists Adaptive Pacing Therapy (APT) for CFS/ME.


 * Burgess & Chalder, 2004. Manual for Therapists Cognitive Behavioral Therapy (CBT) for CFS/ME.


 * Bavinton et al. 2004. Manual for Therapists Graded Exercise Therapy (GET) for CFS/ME.

For participants

 * Cox et al. 2004. Manual for Participants Adaptive Pacing Therapy (APT) for CFS/ME.


 * Burgess & Chalder, 2004. Manual for Participants Cognitive Behavioral Therapy (CBT) for CFS/ME.


 * Bavinton et al. 2004. Manual for Participants Graded Exercise Therapy (GET) for CFS/ME.

For doctors

 * Murphy et al. 2004. Manual for doctors standardised specialist medical care (SSMC).

Newsletters

 * Participants' newsletter Issue 1 June 2006


 * Participants' newsletter Issue 2 March 2007


 * Participants' newsletter Issue 3 December 2008


 * Participants' newsletter Issue 4 February 2011

Trial Steering Committee

 * 1. Trial Steering Committee Meeting 22nd Apr 2004


 * 2. Trial Steering Committee Meeting 27th Sep 2004


 * 3. Trial Steering Committee Meeting 29th Jun 2005


 * 4. Trial Steering Committee Meeting 23rd Jan 2006


 * 5. Trial Steering Committee Meeting 17th Jul 2006


 * 6. Trial Steering Committee Meeting 27th Jun 2007


 * 7. Trial Steering Committee Meeting 9th Apr 2008


 * 8. Trial Steering Committee Meeting 29th Apr 2009


 * 9. Trial Steering Committee Meeting 10th Sep 2010.

Trial Management Group
MInutes from the trial managment group were obtained through a Freedom of Information request. For more information see the following thread on the forum Science for ME: "PACE trial TSC and TMG minutes released."

Draft minutes of PACE team meeting of 7.6.02
 * TMG meeting 1


 * TMG meeting 2


 * TMG meeting 3


 * TMG meeting 4


 * TMG meeting 5


 * TMG meeting 6


 * TMG meeting 7


 * TMG meeting 8


 * TMG meeting 9


 * TMG meeting 10


 * TMG meeting 11


 * TMG meeting 12


 * TMG meeting 13


 * TMG meeting 14


 * TMG meeting 15


 * TMG meeting 16


 * TMG meeting 17


 * TMG meeting 18


 * TMG meeting 19


 * TMG meeting 20


 * TMG meeting 21


 * TMG meeting 22


 * TMG meeting 23


 * TMG meeting 24


 * TMG meeting 25


 * TMG meeting 26


 * TMG meeting 27


 * TMG meeting 28


 * TMG meeting 29


 * TMG meeting 30


 * TMG meeting 31


 * TMG meeting 32


 * TMG meeting 33

Ann Sheridan data for the 6 minute walking test

 * FOI request fom Anne Sheridan to Queen Mary University of London. 6min walking test data - Recovered patients in PACE trial. 3 September 2013.


 * FOI request fom Anne Sheridan to Queen Mary University of London. Raw data for 6mwt. 30 May 2014.


 * FOI request from Anna Sheridan to Queen Mary University of London. Raw 6mwt Data after treatment. 1 November 2015

Other documents

 * Full Trial Consent Form


 * invitation to join the PACE trial


 * Guidance for researchers requesting access to data from the PACE trial