Cytochrome P450 2C19

Cytochrome P450 2C19 or Cytochrome P450 Family 2 Subfamily C Member 19 or CYP2C19 is a gene linked to drug metabolism. Variants in CYP2C19 or lack of the gene are extremely common, with one study finding that over 50%.

Function
Variants in CYP2C19 or the absence of the gene can significantly alter the drug metabolism of several medications, genotype‐based dosing guidelines available for these medications.

ME/CFS
No particular link to ME/CFS has been found for people with CYP2C19 gene variants.

Learn more

 * CYP2C19 - Gene cards