Tarlov cyst

Perineural cysts or Tarlov cysts (TCs) are nerve root dilations resulting from pathologically increased cerebrospinal fluid pressure.

A study of 197 ME/CFS patients found that the prevalence of Tarlov cysts was three times higher in ME/CFS patients than the general population, at 39%.

Tarlov cyst patients often complain about widespread pain and fatigue.

The study's authors conclude:"This observation supports the hypothesis that STCs, FM, and CFS may share the same pathophysiological mechanism, i.e., moderately increased cerebrospinal fluid pressure, causing irritation of neurons and axons in dorsal root ganglia"