Glutamate receptor, ionotropic, kinase 2

Glutamate receptor, ionotropic, kinase 2 or Glutamate Ionotropic Receptor Kainate Type Subunit 2 or GRIK2.

Other names

 * GluK2
 * GLUR6
 * MRT6
 * Glutamate Receptor Ionotropic, Kainate 2
 * Excitatory Amino Acid Receptor 4
 * EAA4
 * Glutamate Receptor 6
 * GluR-6

Function
The glutamate receptors are the main excitatory neurotransmitter receptors in the human brain, and a variety of different GRIK2 gene mutations are associated with different neurodevelopment, neurological and psychiatric conditions.

ME/CFS
A small study by Smith et al. (2011) found people with the G allele of rs2247215 (GRIK2) were more likely to have chronic fatigue syndrome, and CFS patientz had decreased GRIK2 expression patients.

Notable studies

 * 2011, Convergent Genomic Studies Identify Association of GRIK2 and NPAS2 with Chronic Fatigue Syndrome - (Full text)

Learn more

 * GRIK2 - Gene cards