Intravenous immunoglobulin

Intravenous immunoglobulin (IVIG) is a proposed treatment for chronic fatigue syndrome.

Evidence
There is no systematic evidence for the use of IVIG in the treatment of ME or CFS.

Risks & safety
One case study recorded a paradoxical effect where IVIG administration increased the replication of Parvovirus B19, a pathogen associated with CFS.

List of studies

 * Paradoxical response to intravenous immunoglobulin in a case of Parvovirus B19-associated chronic fatigue syndrome, Attard, Luciano et al.Journal of Clinical Virology, Volume 62 , 54 - 57