Vitamin C Deficiency without Scurvy hypothesis

The Vitamin C Deficiency without Scurvy hypothesis is described in and will give the following

symptoms: lassitude, fatigue and irritability.

Evidence
Cited from : Subclinical Vitamin C Deficiency: Clinical Application. Six of seven volunteers noted mild but distinct fatigue and/or irritability at depletion, without scurvy. Symptoms disappeared within several days of the 30- or 60-mg daily dose. Although fatigue and irritability have myriad causes, vitamin C deficiency without scurvy should be an additional consideration.Since fatigue and irritability are common symptoms and were so easily reversible, physicians should ask patients with these symptoms about vitamin C ingestion from foods or supplements.

Blood test
The blood test procedure for Vitamin C deficiency is highly advanced.

Notable studies

 * 1996, Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance

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