Alan Light

Professor Alan R. Light is a Research Professor of Anesthesiology at the Interdepartmental Program in Neuroscience at the University of Utah. He studies the neurobiology of pain and fatigue enhancement caused by injury and in Chronic Fatigue and Fibromyalgia syndromes. Professor Light (and his wife Kathleen White) are known for their work on post-exertional gene expression after exercise.

Talks & interviews

 * Partnerships to Accelerate Biomarker and Mechanisms Discovery in ME/CFS and Fibromyalgia - Alan Light, PhD (5 Dec 2015)
 * Solve ME/CFS Initiative Webinar "New Developments in ME/CFS Research" - Alan Light, PhD (Oct 15, 2015)]

Short web seminars Science to patients / Wetenschap voor patienten English spoken, dutch subtitles


 * 2015, 58. Fatigue / Vermoeidheid - Prof. Alan Light


 * 2015, 59. Genes & Gene-Expression/ Genen en gen-expressie - Prof. Alan Light


 * 2015, 60. Gene expression markers of ME/cfs / Gen-expressie markers van ME/cvs - Prof. Alan Light


 * 2015, 61. Fatigue and Pain in ME/cfs / Vermoeidheid en pijn bij ME/cvs - Prof. Alan Light


 * 2015, 62. ME/cfs and exclusive Conditions / ME/cvs en uitsluitingsaandoeningen - Prof. Alan Light


 * 2015, 63. Effects of ME/cfs on the Brain / Effecten van ME/cvs op de hersenen - Prof. Alan Light


 * 2015, 64. ME/cfs, immune system, cell functioning / ME/cvs, immuunsysteem en cel functioneren - Prof. Alan Light

Publications related to ME/CFS

 * 2016, Iacob, E., Light, A.R., Donaldson, G.W., Okifuji, A., Hughen, R.W., White, A.T., and Light, K.C. (2016) Gene expression factor analysis to differentiate pathways linked to fibromyalgia, chronic fatigue syndrome, and depression in a diverse patient sample. Arthritis Care and Research (Hoboken), Jan;68(1):132-40. doi: 10.1002/acr.22639. PMID: 26097208
 * 2013, Light, K.C., Agarwal, N., Iacob, E., White, A.T., Kinney, A.Y., Vanhaitsma, T.A., Aizad, H., Hughen, R.W., Bateman, L., and Light, A.R. (2013) Differing leukocyte gene expression profiles associated with fatigue in patients with prostate cancer versus chronic fatigue syndrome. Psychoneuroendocrinology, Sep 6. doi:pii: S0306-4530(13)00297-7. 10.1016/j.psyneuen.2013.08.008 [Epub ahead of print
 * 2012, Light AR1, Bateman L, Jo D, Hughen RW, Vanhaitsma TA, White AT, Light KC.(2012) Gene expression alterations at baseline and following moderate exercise in patients with Chronic Fatigue Syndrome and Fibromyalgia Syndrome. Journal of Internal Medicine. 2012 Jan;271(1):64-81. doi: 10.1111/j.1365-2796.2011.02405.x. Epub 2011 Jul 13.
 * 2012, White AT1, Light AR, Hughen RW, Vanhaitsma TA, Light KC (2012) Differences in metabolite-detecting, adrenergic, and immune gene expression after moderate exercise in patients with chronic fatigue syndrome, patients with multiple sclerosis, and healthy controls. Psychosomatic Medicine.74(1):46-54. doi: 10.1097/PSY.0b013e31824152ed. Epub 2011 Dec 30.
 * 2012, Light KC1, White AT, Tadler S, Iacob E, Light AR. Genetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia with and without Comorbid Chronic Fatigue Syndrome. Pain Research and Treatment. 2012;2012:427869. doi: 10.1155/2012/427869
 * 2011, Light,K.C., White,A.T., Tadler,S., Iacob, E. and Light, A.R. (2011) Genetics and Gene Expression Involving Stress and Distress Pathways in Fibromyalgia with and without Comorbid Chronic Fatigue Syndrome. Pain Research and Treatment, Volume 2012, Article ID 427869
 * 2011, Shin CH1, Bateman L, Schlaberg R, Bunker AM, Leonard CJ, Hughen RW, Light AR, Light KC, Singh IR. (2011) Absence of XMRV retrovirus and other murine leukemia virus-related viruses in patients with chronic fatigue syndrome. Journal of Virology. 2011 Jul;85(14):7195-202. doi: 10.1128/JVI.00693-11.
 * 2010, Light, A.R. Vierck, C.J., and Light, K.C. (2010) Chapter 11: Myalgia and Fatigue—Translation from Mouse Sensory Neurons to Fibromyalgia and Chronic Fatigue Syndromes In: Translational Pain Research – From Mouse to Man, Lawrence Kruger and Alan Light, editors; Taylor and Francis.
 * 2010, White, A.T., Light, A.R., Hughen, R.W., Bateman, L., Martins, T.B., Hill, H.R., and Light, K.C. (2010) Severity of symptom flare after moderate exercise is linked to cytokine activity in chronic fatigue syndrome. Psychophysiology, 1–10.
 * 2009, Light, A.R., White, A.T., Hughen, R.W., and Light, K.C. (2009) Moderate Exercise Increases Expression for Sensory, Adrenergic, and Immune Genes in Chronic Fatigue Syndrome Patients But Not in Normal Subjects. The Journal of Pain, 10:1099-1112.

Online presence

 * University of Utah - Alan Light
 * PubMed

Learn more

 * 2014, Sufferers of chronic fatigue, fibromyalgia have hope in new diagnostic tool
 * 2011, Gene expression alterations at baseline and following moderate exercise in patients with Chronic Fatigue Syndrome and Fibromyalgia Syndrome, Journal of Applied Physiology, Volume 271, Issue 1, pages 64–81, January 2012.