Valaciclovir

Valaciclovir (UK) or valacyclovir (US) is a generic antiviral drug used against most herpesviruses. It does not cure herpes, but helps reduce the viral expression, by interrupting the replication of viral DNA.

Valaciclvir is the international nonproprietary name used by the World Health Organization (WHO). The non-generic or trade names are Valtrex and Zelitrex, manufactured by GlaxoSmithKline.

It is available by prescription only, worldwide, and is administered orally.

Once in the body, valaciclovir is converted to aciclovir (UK) or acyclovir (US).

Treatment with Valacyclovir reduces the number of Epstein-Barr virus-infected B cells, but not the number of EBV DNA copies within each infected cell.

Use in ME/CFS
Some ME/CFS specialists prescribe valaciclvir to help mitigate the effects of the Epstein-Barr virus which may be reactivated in ME/CFS. Dr. A Martin Lerner studied the efficacy of higher doses of Valtrex on ME/CFS and concluded that it increased physical functioning, improved heart functioning, and decreased Epstein-Barr virus antibody levels.

Learn more

 * Wikipedia - Valaciclovir
 * Valacyclovir, EBV and CFS
 * Physician's Desk Reference - Valtrex
 * ME/CFS Treatment Resource Guide for Practitioners by Dr. A Martin Lerner
 * Doctor Sarah Myhill - Valacyclovir in the treatment of post viral fatigue syndrome