Corticotropin-releasing factor receptor type 2

Corticotropin-releasing factor receptor type 2 or corticotropin-releasing hormone receptor 2 or CRFR2 or CRHR2 or CRF2 or CRF2 or CRH2 is a protein but CRFR2 may also refer to the gene that encodes the protein.

ME/CFS
CRFR2 may be upregulated in ME/CFS patients - although this has not yet been proven - and the degree of upregulation may be linked to the severity of ME/CFS. The new drug CT38 is currently in clinical trials at the Bateman Horne Center to determine if downregulating CRFR2 is an effective treatment or cure for ME/CFS.

Notable studies

 * 2021, Acute Corticotropin-Releasing Factor Receptor Type 2 Agonism Results in Sustained Symptom Improvement in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (Full text)

Learn more

 * Sep 2021, Cortene Weighs-In on Future Plans for CT38 - Bateman Horne Center
 * Sep 2021, Cortene study published
 * Sep 2021, Dr Bateman on Cortene and CT38