List of systematic reviews about ME/CFS/SEID

List of systematic reviews, literature reviews and other reviews about myalgic encephalomyelitis/chronic fatigue syndrome/Systemic Exertion Intolerance Disease.

Epidemiology reviews

 * 2020, Systematic review and meta-analysis of the prevalence of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) - (Full text)
 * 2013, The adoption of chronic fatigue syndrome/myalgic encephalomyelitis case definitions to assess prevalence: a systematic review - (Full text)
 * 2020, Systematic Review of the Epidemiological Burden of Myalgic encephalomyelitis/chronic fatigue syndrome across Europe: current evidence and EUROMENE research recommendations for epidemiology. (Full text)
 * 2005, A systematic review describing the prognosis of chronic fatigue syndrome - (Full text)

Diagnotic criteria reviews

 * 2018, ME/CFS, case definition, and serological response to Epstein-Barr virus. A systematic literature review - (Full text)
 * 2014, Case definitions for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME): a systematic review - (Abstract)

Neurological

 * 2022, Review of the Midbrain Ascending Arousal Network Nuclei and Implications for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Gulf War Illness (GWI) and Postexertional Malaise (PEM) - (Full text)
 * 2020, Neuroimaging characteristics of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a systematic review (Full text)
 * 2020, A systematic review of neurological impairments in myalgic encephalomyelitis/chronic fatigue syndrome using neuroimaging techniques - (Full text)
 * 2019, Evidence of altered cardiac autonomic regulation in myalgic encephalomyelitis/chronic fatigue syndrome: A systematic review and meta-analysis - (Full text)
 * 2019, Neuroinflammation and Cytokines in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Critical Review of Research Methods - (Full text), (plus correction)
 * 2014, Malfunctioning of the autonomic nervous system in patients with chronic fatigue syndrome: a systematic literature review - (Full text)
 * 1994, A comparative review of systemic and neurological symptomatology in 12 outbreaks collectively described as chronic fatigue syndrome, epidemic neuromyasthenia, and myalgic encephalomyelitis - (Full text)

Immunological

 * 2019, Inflammatory proteins are altered in chronic fatigue syndrome–a systematic review and meta-analysis - (Full text)
 * 2015, Chronic fatigue syndrome and circulating cytokines: a systematic review - (Full text)
 * 2014, Altered immune response to exercise in patients with chronic fatigue syndrome/myalgic encephalomyeltitis: A systematic literature review - (Full text)
 * 2007, Chronic musculoskeletal pain in patients with the chronic fatigue syndrome: a systematic review - (Full text)
 * 2003, A systematic review and critical evaluation of the immunology of chronic fatigue syndrome - (Abstract)

Viruses and other infections

 * 2018, The role of herpesviruses 6 and 7 in the development of chronic fatigue syndrome: a review of literature and description of clinical cases - (Abstract, English), (Full text, original)
 * 2016, The Association Between Borna Disease Virus and Chronic Fatigue Syndrome: A Systematic Review and Meta-Analysis - (Full text)

Heart/Circulatory

 * 2014, Malfunctioning of the autonomic nervous system in patients with chronic fatigue syndrome: a systematic literature review - (Full text)
 * 2013, Heart rate variability in patients with fibromyalgia and patients with chronic fatigue syndrome: a systematic review - (Full text)

Metabolic

 * 2020, A systematic review of metabolomic dysregulation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis/Systemic Exertion Intolerance Disease (CFS/ME/SEID) - (Full text)
 * 2018, Chronic Fatigue and Immune Deficiency Syndrome (CFIDS), Cellular Metabolism, and Ionizing Radiation: A Review of Contemporary Scientific Literature and Suggested Directions for Future Research - (Full text)

Gastrointestinal / Digestive

 * 2018, A systematic review of enteric dysbiosis in chronic fatigue syndrome/myalgic encephalomyelitis - (Full text)
 * 2017, Vitamin and mineral status in chronic fatigue syndrome and fibromyalgia syndrome: A systematic review and meta-analysis - (Full text)

Exercise capacity, fitness or strength

 * 2011, Tired of being inactive: a systematic literature review of physical activity, physiological exercise capacity and muscle strength in patients with chronic fatigue syndrome - (Full text)

Psychiatric, psychological and personality

 * 2016, The association between borderline personality disorder, fibromyalgia and chronic fatigue syndrome: systematic review - (Full text)
 * 2008, A systematic review of chronic fatigue syndrome: don't assume it's depression - (Full text)

Cognitive or neurocognitive functioning

 * 2013, Caught in the thickness of brain fog: exploring the cognitive symptoms of Chronic Fatigue Syndrome (Full text)
 * 2013, Neurocognitive impairment in childhood chronic fatigue syndrome (Full text)
 * 2013, Cognitive impairments associated with CFS and POTS (Full text)
 * 2016, Cognitive dysfunction in chronic fatigue syndrome (Full text)
 * 2022, Systematic review and meta‐analysis of cognitive impairment in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) - (Full text)

Recovery, employment and disability rates

 * 2022, Is It Useful to Question the Recovery Behaviour of Patients with ME/CFS or Long COVID? - (Full text)

General

 * 2002, AHRQ review - Systematic review of the current literature related to disability and chronic fatigue syndrome - (Full text)

Randomized controlled trial reviews

 * 2020, Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) - (Full text)
 * 2020, Assessment of the scientific rigour of randomized controlled trials on the effectiveness of cognitive behavioural therapy and graded exercise therapy for patients with myalgic encephalomyelitis/chronic fatigue syndrome: A systematic review - (Abstract)

Drug and Chinese medicine systematic reviews

 * 2020, Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) - (Full text)
 * 2016, A Systematic Review of Drug Therapies for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis - (Full text)
 * 2014, Traditional Chinese medicine for chronic fatigue syndrome: a systematic review of randomized clinical trials - (Abstract)

Diet or nutritional supplement reviews

 * 2021, A systematic review of nutraceutical interventions for mitochondrial dysfunctions in myalgic encephalomyelitis/chronic fatigue syndrome - (Full text)
 * 2018, Are probiotic treatments useful on fibromyalgia syndrome or chronic fatigue syndrome patients? A systematic review - (Abstract)
 * 2020, Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) - (Full text)
 * 2017, Dietary and nutrition interventions for the therapeutic treatment of chronic fatigue syndrome/myalgic encephalomyelitis: a systematic review - (Full text)
 * 2017, Role of dietary modification in alleviating chronic fatigue syndrome symptoms: a systematic review - (Full text)
 * 2016, A systematic review of probiotic interventions for gastrointestinal symptoms and irritable bowel syndrome in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) - (Abstract)

Alternative or complementary therapies

 * 2020, Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) - (Full text)
 * 2011, Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review - (Full text)

Psychological, behavioral and exercise treatment reviews

 * 2022, Is It Useful to Question the Recovery Behaviour of Patients with ME/CFS or Long COVID? - (Full text)
 * 2021, Systematic Review of Mind-Body Interventions to Treat Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - (Full text)
 * 2020, Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) - (Full text)
 * 2019, Work Rehabilitation and Medical Retirement for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients. A Review and Appraisal of Diagnostic Strategies - (Full text)
 * 2019, Cognitive behavioural therapy for myalgic encephalomyelitis/chronic fatigue syndrome is not effective. Re-analysis of a Cochrane review - (Full text)
 * 2018, Rethinking the treatment of chronic fatigue syndrome — A reanalysis and evaluation of findings from a recent major trial of graded exercise and CBT - (Full Text)
 * 2018, Graded exercise therapy for myalgic encephalomyelitis/chronic fatigue syndrome is not effective and unsafe. Re-analysis of a Cochrane review (Full Text)
 * 2017, Assessment of Individual PACE Trial Data: in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Cognitive Behavioral and Graded Exercise Therapy are Ineffective, Do Not Lead to Actual Recovery and Negative Outcomes may be Higher than Reported (Full text)
 * 2018, The effect of physiotherapy on fatigue and physical functioning in chronic fatigue syndrome patients: a systematic review - (Full text)
 * 2017, Do evidence based interventions for chronic fatigue syndrome improve sleep? A systematic review and narrative synthesis - (Full text)
 * 2009, A review on cognitive behavorial therapy (CBT) and graded exercise therapy (GET) in myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS): CBT/GET is not only ineffective and not evidence-based, but also potentially harmful for many patients with ME/CFS - (Full text)

Other treatment reviews

 * 2020, Systematic review of randomized controlled trials for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) - (Full text)
 * 2018, The effect of physiotherapy on fatigue and physical functioning in chronic fatigue syndrome patients: a systematic review - (Full text)
 * 2015, Pathways to prevention report - Treatment of myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review for a National Institutes of Health Pathways to Prevention Workshop - (Full text)


 * 2003, York Review - Interventions for the treatment, management and rehabilitation of patients with chronic fatigue syndrome/myalgic encephalomyelitis: an updated systematic review - (Full text)
 * 2006, York Review - Interventions for the treatment, management and rehabilitation of patients with chronic fatigue syndrome/myalgic encephalomyelitis: an updated systematic review - (Full text)
 * The York Review was used as the evidence based for the UK's 2007 NICE guidelines, and was based on data provided by Simon Wessely.
 * 2006, Inadequacy of the York (2005) Systematic Review of the CFS/ME Medical Evidence Base (Full text)

Psychological and sociological reviews

 * 2012, A review and meta-synthesis of qualitative studies on myalgic encephalomyelitis/chronic fatigue syndrome - (Full text)
 * 2012, Quality and acceptability of patient-reported outcome measures used in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME): a systematic review - (Full text)
 * 2009, A review on cognitive behavorial therapy (CBT) and graded exercise therapy (GET) in myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS): CBT/GET is not only ineffective and not evidence-based, but also potentially harmful for many patients with ME/CFS - (Full text)
 * 2009, The expressed needs of people with chronic fatigue syndrome/myalgic encephalomyelitis: a systematic review - (Full text)
 * 2008, A systematic review of chronic fatigue syndrome: don't assume it's depression - (Full text)

General reviews

 * 2014, Chronic fatigue syndrome: A review - (Full text)

Pediatric

 * 2017, Children's experiences of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME): a systematic review and meta-ethnography of qualitative studies - (Full text)
 * 2016, Treatment for paediatric chronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) and comorbid depression: a systematic review - (Full text)
 * 2013, Interventions in pediatric chronic fatigue syndrome/myalgic encephalomyelitis: a systematic review - (Abstract)

Severe Myalgic Encephalomyelitis

 * 2021, Systematic Review of Sleep Characteristics in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (Full text)

General

 * 2016, Chronic Fatigue Syndrome (CFS) or "Systemic Immune Disorder" (SID)? - (Full text)