Methylene blue

Methylene blue or methylthioninium chloride (MB) is a medication and dye that also functions as an antioxidant.

Theory
Methylene blue is claimed to lead to better oxygenation of tissues, mitochondrial protection and recovery, improved memory and cognition. It is used sublingually by some ME/CFS patients.

Evidence
No clinical trials of methylene blue have been conducted in ME/CFS patients.

Risks and safety
Serotonin syndrome and a number of other serious side effects may result from the use of methylene blue. It also turns skin and mucosa a bluish color and urine a greenish blue color.

Learn more

 * Methylene blue - drugs.com
 * Methylene blue - drugbank.ca
 * Methylene blue - Chemical Entities of Biological Interest (ChEBI)
 * Methylene blue: Revisited- Journal of Anaesthesiology, Clinical Pharmacology