Autoimmune hypothesis

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Theory
Explain the theory or multiple theories re: autoimmunity in ME or CFS

Evidence
Write a narrative summary of the evidence, citing all facts and studies used

Published Studies

 * 2014, The emerging role of autoimmunity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/cfs) (Morris G, Berk M, Galecki P, Maes M)
 * 2013, In myalgic encephalomyelitis/chronic fatigue syndrome, increased autoimmune activity against 5-HT is associated with immuno-inflammatory pathways and bacterial translocation (Maes M, Ringel K, Kubera M, Anderson G, Morris G, Galecki P, Geffard M)
 * 2012, Increased autoimmune activity against 5-HT: a key component of depression that is associated with inflammation and activation of cell-mediated immunity, and with severity and staging of depression (Maes M, Ringel K, Kubera M, Berk M, Rybakowski J)
 * 2004, Is chronic fatigue syndrome an autoimmune disorder of endogenous neuropeptides, exogenous infection and molecular mimicry? (Donald Staines)

Talks & Interviews

 * 2015, Partnerships to Accelerate Biomarker and Mechanisms Discovery in ME/CFS and Fibromyalgia - Alan Light, PhD (5 Dec 2015. Professor Alan Light discusses recent studies hypothesising autoimmune causation)