Microglia

Microglia are a type of glial cell located in the brain and spinal cord. They are the macrophages of the central nervous system.

Chronic fatigue syndrome
Chronic inflammation of microglia has been found in ME/CFS patients.

Valcyte (valganciclovir), a drug commonly used as an off-label treatment for ME/CFS and Cytovene (ganciclovir) inhibit microglial activation. Low-dose naltrexone (LDN, another off-label treatment,) inhibits microglial activation via the TLR4 receptor.