Modafinil

Modafinil is a non-stimulant medication used to improve wakefulness in adult patients with excessive sleepiness associated with narcolepsy, obstructive sleep apnea, or shift work disorder (SWD). In the United States, it is marketed with the name Provigil.

Evidence
Modafinal is a suggested treatment for fatigue (increased energy and alertness) in the Canadian Consensus Criteria, with 100mg suggested in the morning and adding another 100mg at noon.

Notable studies

 * 2000, Effect of Modafinil on Fatigue Associated with Neurological Illnesses