Tenascin-X

The TNXB gene is a protein-encoding gene for the protein tenascin-X. This protein plays an important role in organizing and maintaining the structure of tissues that support the body's muscles, joints, organs, and skin (connective tissues). In particular, studies suggest that it helps to regulate the production and assembly of certain types of collagen. Collagens are a family of proteins that strengthen and support connective tissues throughout the body. Tenascin-X is also involved in regulating the structure and stability of elastic fibers, which provide flexibility and stretchiness (elasticity) to connective tissues.

Alternative names
The gene TNXB is also known as:
 * Hexabrachion-like
 * HXBL
 * Tenascin XB
 * Tenascin XB1
 * Tenascin XB2
 * TENX
 * TENX_HUMAN
 * TNX
 * TNXB1
 * TNXB2
 * TNXBS
 * XB
 * XBS

Function
Mutations in TNXB are associated with the connective tissue disease Ehlers-Danlos syndrome (EDS).

Learn more

 * TNXB gene - MedlinePlus
 * TNXB gene - Gene cards