Zofran

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Zofran or ondansetron (generic name, oral) is drug used to treat nausea and vomiting.[1] It is a 5-HT3 receptor antagonist.[2] Zofran is also sold under the brand names Zofran ODT and Zuplenz.[1]

Theory[edit | edit source]

Evidence[edit | edit source]

Clinicians[edit | edit source]

Risks and safety[edit | edit source]

Serious side effects may occur with zofran including:

  • blurred vision or vision loss (lasting from a few minutes to several hours)
  • Slowed heart rate
  • Difficultty breathing
  • Anxiety
  • Agitation
  • Shivering
  • feeling like you might pass out
  • Urinating less than usual or not urinating at all

Zofran may impair your thinking or reactions, which may make driving unsafe.[1]

Costs and availability[edit | edit source]

Notable studies[edit | edit source]

  • 2009, Treatment of chronic fatigue syndrome with 5-HT3 receptor antagonists - preliminary results[2](Abstract)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]

  1. 1.01.11.2 "Zofran Uses, Dosage & Side Effects". Drugs.com. Retrieved November 29, 2020.
  2. 2.02.1 Späth, M.; Färber, D., L.; Welzel, D. (January 1, 2000). "Treatment of chronic fatigue syndrome with 5-HT3 receptor antagonists - preliminary results". Scandinavian Journal of Rheumatology. 29 (113): 72–77. doi:10.1080/030097400750001851-1. ISSN 0300-9742.

antagonist A chemical that reduces or helps block the activity of another chemical in the body. For example, most antihistamines are H1 antagonists because they block the H1 histamine receptor, which helps relieve allergy symptoms. The opposite of an agonist.

adverse reaction Any unintended or unwanted response to a treatment, whether in a clinical trial or licensed treatment. May be minor or serious.

antagonist A chemical that reduces or helps block the activity of another chemical in the body. For example, most antihistamines are H1 antagonists because they block the H1 histamine receptor, which helps relieve allergy symptoms. The opposite of an agonist.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.