Vitamin D receptor

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The Vitamin D receptor (VDR) is a cell receptor that turns on the expression of certain pathways when activated by Vitamin D.

Individuals who are heterozygous or homozygous for the VDR mutation have lower Vitamin D levels, make less dopamine, and are more tolerant of methyl donors.

VDR may be required for the normal development of natural killer T cells that react to cells expressing CD1d, as in cells infected by certain viruses.[1]

An Epstein barr virus protein EBNA-3 has an affinity for VDR and may actually block the activation of VDR-dependent genes by Vitamin D.[2]


References[edit]

[3]
  1. http://www.pnas.org/content/105/13/5207.short
  2. http://www.ncbi.nlm.nih.gov/pubmed/20593215
  3. Reference needed


The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history