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Allodynia refers to pain caused by what would normally be non-painful stimulation, for example brushing the skin.[1] Temperature change, light touching, and clothing can trigger the pain response resulting in a burning sensation often occurring after an injury to a site.[2]

Presentation[edit | edit source]

There are three types of allodynia. Tactile, where pain is caused by touches such as clothing touching the skin or someone lightly touching the arm; Mechanical, caused by movement across the skin when drying with a towel or sheets brushing against the skin; and Thermal, which is caused by heat or cold that is not extreme enough to cause damage to skin tissues.[3]

Allodynia in ME/CFS and Fibromyalgia[edit | edit source]

Allodynia is not a diagnostic symptom of ME or CFS, and is not even referred to in the International Consensus Criteria Primer for ME although over forms of pain are.[4]

Prevalence[edit | edit source]

A study of over 3,000 patients with fibromyalgia found that allodynia was "surprisingly common."[5]

Notable studies[edit | edit source]

  • 2009, Models and Mechanisms of Hyperalgesia and Allodynia[1](Full text)
  • 2010, A cross-sectional survey of 3035 patients with fibromyalgia: subgroups of patients with typical comorbidities and sensory symptom profiles[5](Full text)

Possible causes[edit | edit source]

Central pain sensitization (increased response of neurons) has been proposed as a possible cause, but this term has conflicting definitions and scientific evidence is unclear.[1][2]

Potential treatments[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

chronic fatigue syndrome (CFS) - A fatigue-based illness. The term CFS was invented invented by the U.S. Centers for Disease Control as an replacement for myalgic encephalomyelitis (ME). Some view CFS as a neurological disease, others use the term for any unexplained long-term fatigue. Sometimes used as a the term as a synonym of myalgic encephalomyelitis, despite the different diagnostic criteria.

International Consensus Criteria (ICC) - A set of diagnostic criteria, based on the Canadian Consensus Criteria, that argued for the abandonment of the term "chronic fatigue syndrome" and encouraged the sole use of the term "myalgic encephalomyelitis".

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.