Swollen lymph nodes

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Swollen, painful, and/or tender lymph nodes are a common occurrence in ME/CFS.

Presentation[edit]

Prevalence[edit]

  • 57.7% - 67.9% of the 2073 patients in a Belgian study of 2001 reported swollen/tender lymph nodes.[1]
  • Katrina Berne reports a prevalence of 50-80% for painful and/or swollen lymph nodes.[2]

Symptom recognition[edit]

  • In the Canadian Consensus Criteria, tender lymph nodes are an optional criteria for diagnosis, under the section Immune Manifestations.[3]
  • In the Fukuda criteria, the symptom of tender lymph nodes can be used to help form a diagnosis.[4]
  • In the Holmes criteria, painful lymph nodes in the anterior or posterior cervical or axillary distribution is an optional criteria for diagnosis, under the section Minor Symptom Criteria. It also appears as an optional criteria for diagnosis under the section Minor Physical Criteria as palpable or tender anterior or posterior cervical or axillary lymph nodes that have been documented by a physician on at least two occasions, at least one month apart.[5]

Notable studies[edit]

Possible causes[edit]

Potential treatments[edit]

Learn more[edit]

See also[edit]

References[edit]

  1. De Becker, P; McGregor, N; De Meirleir, K (Sep 2001), "A definition-based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome.", Journal of Internal Medicine, 250 (3): 234-240, PMID 11555128 
  2. Berne, Katrina (1 Dec 1995), Running on Empty: The Complete Guide to Chronic Fatigue Syndrome (CFIDS), 2nd ed., Hunter House, p. 58, ISBN 978-0897931915 
  3. A Clinical Case Definition and Guidelines for Medical Practitioners: An Overview of the Canadian Consensus Document Pg 8. 2005.
  4. The CDC (Fukuda 1994) Definition for Chronic Fatigue Syndrome
  5. The 1988 Holmes Definition for CFS


The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history