Sophora flavescens

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history
Jump to: navigation, search

Sophora flavescens (common name: shrubby sophora) is a plant in the genus Sophora, a genus of the Fabaceae family, that contains about 52 species, nineteen varieties, and seven forms that are widely distributed in Asia, Oceanica, and the Pacific islands. About fifteen species in this genus have a long history of use in Traditional Chinese Medicine. Sophora flavescens root is known as Ku Shen in traditional Chinese medicine. Compounds in Sophora flavescens possessing medicinal properties include oxymatrine, matrine and sophoridine.

Sophora flavescens is the primary component of Equilibrant, an oxymatrine-based product used for treating ME/CFS.

Immunomodulatory properties[edit | edit source]

Antiviral properties[edit | edit source]

Antimicrobial properties[edit | edit source]

It is active against staphylococcus aureus infection.[1][2][3]

Theory[edit | edit source]

Evidence[edit | edit source]

Clinicians[edit | edit source]

Risks and safety[edit | edit source]

Costs and availability[edit | edit source]

Equilibrant[edit | edit source]

Sophora flavescens is the main ingredient in equilibrant, a supplement developed for patients with ME/CFS.

See also[edit | edit source]

References[edit | edit source]

  1. Chen, Li; Cheng, Xiaofang; Shi, Wenyuan; Lu, Qingyi; Go, Vay Liang; Heber, David; Ma, Lili (July 2005), "Inhibition of Growth of Streptococcus mutans, Methicillin-Resistant Staphylococcus aureus, and Vancomycin-Resistant Enterococci by Kurarinone, a Bioactive Flavonoid Isolated from Sophora flavescens", Journal of Clinical Microbiology, 43 (7): 3574–3575, doi:10.1128/JCM.43.7.3574-3575.2005, ISSN 0095-1137, PMC 1169149Freely accessible, PMID 16000511, retrieved Nov 9, 2016 
  2. Fakhimi, Ali; Iranshahi, Mehrdad; Emami, Seyed Ahmad; Amin-Ar-Ramimeh, Esam; Zarrini, Gholamreza; Shahverdi, Ahmad Reza (October 2006), "Sophoraflavanone G from sophora pachycarpa enhanced the antibacterial activity of gentamycin against Staphylococcus aureus", Zeitschrift Fur Naturforschung. C, Journal of Biosciences, 61 (9-10): 769–772, ISSN 0939-5075, PMID 17137127 
  3. Yamaki, Masae; Kashihara, Mikiko; Takagi, Shuzo (Dec 1, 1990), "Activity of Ku Shen compounds against Staphylococcus aureus and Streptococcus mutans", Phytotherapy Research, 4 (6): 235–236, doi:10.1002/ptr.2650040607, ISSN 1099-1573, retrieved Nov 9, 2016 

immunomodulator - a substance that affects the functioning of the immune system

ME/CFS - An acronym that combines myalgic encephalomyelitis with chronic fatigue syndrome. Sometimes they are combined because people have trouble distinguishing one from the other. Sometimes they are combined because people see them as synonyms of each other.

The information provided at this site is not intended to diagnose or treat any illness.
From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history.