Proline-rich transmembrane protein 4

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history

Proline-rich transmembrane protein 4 or PRRT4 is an obscure gene that may be linked to chronic fatigue syndrome.[1][2]

Function[edit | edit source]

ME/CFS[edit | edit source]

The first publication from the long term ME/CFS Gene Study, which used the Fukuda criteria for chronic fatigue syndrome only, looked for the SNPs that were more common in CFS patients than in healthy people, and which were most likely to be harmful. PRRT4 was one of the top ten genes most likely to be harmful that more common in CFS patients, occurring in over 70% of patients.[1]

Notable studies[edit | edit source]

  • 2019, Genetic Predisposition for Immune System, Hormone, and Metabolic Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Pilot Study[1] (Full text)

See also[edit | edit source]

Learn more[edit | edit source]

References[edit | edit source]