Neuro-Inflammatory and Oxidative Fatigue

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Neuro-Inflammatory and Oxidative Fatigue (NIOF) is a name and case definition proposed by Michael Maes in 2015.[1] In his paper the author stated "The aim of the present study was to delineate a new case definition of ME/CFS based on pattern recognition methods and using neuro-immune, inflammatory, oxidative and nitrosative stress (neuro-IO&NS) biomarkers as external validating criteria".

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From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history