Memory problems

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Memory problems in myalgic encephalomyelitis can be very disabling. Mental fatigue makes memory problems worse but does not account for all memory deficiencies in people with ME/CFS. A 2006 study by the CDC found that patients with CFS and high complaints of mental fatigue exhibited significant impairment in working memory.[1]

Presentation[edit | edit source]

Prevalence[edit | edit source]

  • In a 2001 Belgian study, 85.6% of patients meeting the Fukuda criteria and 89.3% of patients meeting the Holmes criteria, in a cohort of 2073 CFS patients, reported memory problems.[2]

Symptom recognition[edit | edit source]

  • In the Canadian Consensus Criteria, impairment of concentration and short-term memory consolidation is an optional criteria for diagnosis, under the section Neurological/Cognitive Manifestations.[3]
  • In the Fukuda criteria, the symptom of substantial impairment in short-term memory can be used to help form a diagnosis.[4]
  • In the Holmes criteria, forgetfulness is an optional criteria for diagnosis, under the section Minor Symptom Criteria - Neuropsychologic Complaints.[5]

Notable studies[edit | edit source]

Possible causes[edit | edit source]

Potential treatments[edit | edit source]

Learn more[edit | edit source]

See also[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1 Capuron, Lucile; Welberg, Leonie; Heim, Christine; Wagner, Dieter; Solomon, Laura; Papanicolaou, Dimitris A; Craddock, R Cameron; Miller, Andrew H; Reeves, William C (2006), "Cognitive Dysfunction Relates to Subjective Report of Mental Fatigue in Patients with Chronic Fatigue Syndrome", Neuropsychopharmacology, 31: 1777–1784, doi:10.1038/sj.npp.1301005 
  2. De Becker, P; McGregor, N; De Meirleir, K (Sep 2001), "A definition-based analysis of symptoms in a large cohort of patients with chronic fatigue syndrome.", Journal of Internal Medicine, 250 (3): 234-240, PMID 11555128 
  3. A Clinical Case Definition and Guidelines for Medical Practitioners: An Overview of the Canadian Consensus Document Pg 8. 2005.
  4. The CDC (Fukuda 1994) Definition for Chronic Fatigue Syndrome
  5. The 1988 Holmes Definition for CFS


The information provided at this site is not intended to diagnose or treat any illness.

From MEpedia, a crowd-sourced encyclopedia of ME and CFS science and history